ZNF193 antibody - middle region (ARP35793_P050)
- Known as:
- ZNF193 (anti-) - middle region (ARP35793_P050)
- Catalog number:
- arp35793_p050
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Aviva Systems Biology
- Gene target:
- ZNF193 antibody - middle region (ARP35793_P050)
Related genes to: ZNF193 antibody - middle region (ARP35793_P050)
- Gene:
- ZSCAN9 NIH gene
- Name:
- zinc finger and SCAN domain containing 9
- Previous symbol:
- ZNF193
- Synonyms:
- PRD51
- Chromosome:
- 6p22.1
- Locus Type:
- gene with protein product
- Date approved:
- 1997-02-14
- Date modifiied:
- 2016-10-05
Related products to: ZNF193 antibody - middle region (ARP35793_P050)
Related articles to: ZNF193 antibody - middle region (ARP35793_P050)
- Graves' Ophthalmopathy (GO) is classified as an autoimmune condition that involves inflammation and structural changes within the orbit, frequently linked to thyroid abnormalities. The objective of this research is to clarify the genetic foundations associated with GO. - Source: PubMed
Publication date: 2025/12/01
Yuan JieqingMeng LinglingChen Yuting - Zinc finger and SCAN domain containing 9 (), also known as (), has been associated with the enhanced expression of X-chromosomal genes in certain organs. However, its role in hepatocellular carcinoma (HCC) remains unclear. This study examines the mechanism of in HCC and analyze its expression, prognostic value, clinical relevance, immune correlation, signaling pathways, and drug sensitivity, thus providing new insights into its potential as a therapeutic target for HCC. - Source: PubMed
Publication date: 2025/08/28
Jing SuweiDong WenleiZhan Chao - Semen quality is one of the most important indicators of boar reproductive performance. In the past, boar breeding has mostly emphasized characteristics such as lean meat percentage, feed conversion efficiency, and growth rate, while overlooking the genetic improvement of reproductive traits. This study employs advanced multi-omics approaches, such as transcriptome-wide association studies (TWAS) and colocalization between genome-wide association studies (GWAS) and expression quantitative trait loci (eQTLs), to provide a comprehensive understanding of the genetic mechanisms governing semen quality traits in boars. - Source: PubMed
Publication date: 2025/07/21
Li XuehuaLin QingZhuang ZhanweiRao KaiLi ZhiliShang XiuguoXia PanjieZhu LinZhang ZheZhao Yunxiang - Recent research suggests a potential link between the gut microbiome (GM) and epilepsy. We undertook a Mendelian randomization (MR) study to determine the possible causal influence of GM on epilepsy and its various subtypes, and explore whether cytokines act as mediators. - Source: PubMed
Publication date: 2024/05/24
Qiu YoujiaSong BingyiXie MinjiaTao YuchenYin ZiqianWang MenghanMa ChaoChen ZhouqingWang Zhong - The knowledge of genetic variants shaping human placental transcriptome is limited and they are not cataloged in the Genotype-Tissue Expression project. So far, only one whole genome analysis of placental expression quantitative trait loci (eQTLs) has been published by Peng et al. (2017) with no external independent validation. We report the second study on the landscape of placental eQTLs. The study aimed to generate a high-confidence list of placental -eQTLs and to investigate their potential functional implications. Analysis of -eQTLs (±100 kbp from the gene) utilized 40 placental RNA sequencing and respective whole genome genotyping datasets. The identified 199 placental -eSNPs represented 88 independent eQTL signals (FDR < 5%). The most significant placental eQTLs (FDR < 10) modulated the expression of ribosomal protein RPL9, transcription factor ZSCAN9 and aminopeptidase ERAP2. The analysis confirmed 50 eSNP-eGenes pairs reported by Peng et al. (2017) and thus, can be claimed as robust placental eQTL signals. The study identified also 13 novel placental eGenes. Among these, is modulated by several eSNPs (experimentally validated: rs1150707) that have been also shown to affect the methylation level of genes variably escaping X-chromosomal inactivation. The identified 63 placental eGenes exhibited mostly mixed or ubiquitous expression. Functional enrichment analysis highlighted 35 Gene Ontology categories with the top ranking pathways "ruffle membrane" (FDR = 1.81 × 10) contributing to the formation of motile cell surface and "ATPase activity, coupled" (FDR = 2.88 × 10), critical for the membrane transport. Placental eGenes were also significantly enriched in pathways implicated in development, signaling and immune function. However, this study was not able to confirm a significant overrepresentation of genome-wide association studies top hits among the placental eSNP and eGenes, reported by Peng et al. (2017). The identified eSNPs were further analyzed in association with newborn and pregnancy traits. In the discovery step, a suggestive association was detected between the eQTL of (rs11678251) and reduced placental, newborn's and infant's weight. Meta-analysis across REPROMETA, HAPPY PREGNANCY, ALSPAC cohorts ( = 6830) did not replicate these findings. In summary, the study emphasizes the role of genetic variation in driving the transcriptome profile of the human placenta and the importance to explore further its functional implications. - Source: PubMed
Publication date: 2019/06/11
Kikas TriinRull KristiinaBeaumont Robin NFreathy Rachel MLaan Maris