FOXL1 antibody - N-terminal region (ARP32303_T100)
- Known as:
- FOXL1 (anti-) - N-terminal region (ARP32303_T100)
- Catalog number:
- arp32303_t100
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Aviva Systems Biology
- Gene target:
- FOXL1 antibody - N-terminal region (ARP32303_T100)
Related genes to: FOXL1 antibody - N-terminal region (ARP32303_T100)
- Gene:
- FOXL1 NIH gene
- Name:
- forkhead box L1
- Previous symbol:
- FKHL11
- Synonyms:
- FREAC7, FKH6
- Chromosome:
- 16q24.1
- Locus Type:
- gene with protein product
- Date approved:
- 1995-06-05
- Date modifiied:
- 2016-10-05
Related products to: FOXL1 antibody - N-terminal region (ARP32303_T100)
Related articles to: FOXL1 antibody - N-terminal region (ARP32303_T100)
- Postmenopausal Osteoporosis (PMOP) is an age-related disease prevalent among elderly women, characterized by decreased bone density and increased fracture risk. This study investigates the mechanisms of traditional Chinese medicine (TCM) in treating PMOP. - Source: PubMed
Publication date: 2026/05/08
Xiao HefangWang YaobinChen YiGeng BinXia Yayi - This study aimed to elucidate the molecular mechanisms driving the comorbidity of pulmonary arterial hypertension and cardiomyopathy (PAH-CMP), identify key pathogenic genes, and explore potential therapeutic agents targeting these genes. - Source: PubMed
Publication date: 2026/04/10
Hu JianchuanZhang WanqunZeng QiurongYang MinZhang LiliXu Yunhu - Preeclampsia (PE) is a major pregnancy complication that poses risks to both the mother and the fetus. Oxidative stress (OS) plays a crucial role in its pathogenesis. This study aims to explore the diagnostic value of oxidative stress-related genes for PE. - Source: PubMed
Ye WenhuaYin Haiyan - Chinese tongue sole () is an important mariculture product in northern China, exhibiting significant sexual dimorphism: females grow 2-4 times faster than males and ultimately attain much greater body weights. As a well-known transcription factor crucial for regulating sex differentiation, has been characterized in various mammals. Herein, we identified and characterized three genes, , and . Three genes exhibited a gonad-biased expression pattern, where showed higher expression in ovary than in testis, while and exhibited higher expression in testis. All genes were detected in testes and ovaries by ISH; / were expressed in oocytes and sperm, and in granulosa cells and sperm. Overexpression of in testicular cells led to KEGG enrichment in DNA repair, MAPK, FOXO and progesterone-mediated oocyte maturation pathways. In tongue sole testicular cell line, knockdown of and resulted in upregulation of multiple male-related genes. In contrast, knockdown of led to decreased expression of aromatase genes and increased expression of , indicating that is more closely associated with female differentiation and maintenance. Our study investigated the functions of the gene family in teleosts and offers valuable insights into their role in sex differentiation and gonadal maintenance in teleost fish. - Source: PubMed
Publication date: 2026/02/14
Yan HaipengWang LijunSun XuexueHe MingyueYang YingmingMeng ZhenLi XihongWang NaDong ZhongdianXu Wenteng - The primitive gut tube of mammals initially forms as a simple cylinder consisting of the endoderm-derived, pseudostratified epithelium and the mesoderm-derived surrounding mesenchyme. During mid-gestation, a dramatic transformation occurs in which the epithelium is both restructured into its final cuboidal form and simultaneously folded and refolded to create intestinal villi and intervillus regions. Here, we show that the mesenchymal winged helix transcription factor Foxl1, itself induced by epithelial hedgehog signaling, controls villification by activating BMP and PDGFRα and the planar cell polarity factor Fat4 in epithelial-adjacent telocyte progenitors either directly or indirectly. In the absence of Foxl1-dependent mesenchymal signaling, villus formation and the separation of epithelial cells into mitotic intervillus and postmitotic villus are delayed, and the differentiation of secretory progenitors temporarily blocked. Thus, Foxl1 orchestrates key events during the epithelial transition of the fetal mammalian gut. - Source: PubMed
Publication date: 2026/02/24
Zhu GuoliRozenberg GalinaLahori DeekshaSchug JonathanTigue MarkCheng LanBatmanov KirillKaestner Klaus H