FOXP4 antibody - middle region (ARP31540_P050)
- Known as:
- FOXP4 (anti-) - middle region (ARP31540_P050)
- Catalog number:
- arp31540_p050
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Aviva Systems Biology
- Gene target:
- FOXP4 antibody - middle region (ARP31540_P050)
Related genes to: FOXP4 antibody - middle region (ARP31540_P050)
- Gene:
- FOXP4 NIH gene
- Name:
- forkhead box P4
- Previous symbol:
- -
- Synonyms:
- FLJ40908
- Chromosome:
- 6p21.1
- Locus Type:
- gene with protein product
- Date approved:
- 2003-05-28
- Date modifiied:
- 2015-09-11
Related products to: FOXP4 antibody - middle region (ARP31540_P050)
Related articles to: FOXP4 antibody - middle region (ARP31540_P050)
- - Source: PubMed
Publication date: 2026/03/07
Wang JunWang MinshenDong QiufengHuo JunliYan ZhifengLi JuanChen XiaoyanLi LiwenZhen Haining - Sexual maturation in boars impacts reproductive efficiency in swine production, yet the molecular mechanisms underlying this developmental transition remain poorly understood. This study aimed to investigate the transcriptomic changes in sperm from Duroc boars during sexual maturation, conducting a longitudinal analysis. The total RNA and miRNA profiles from the same individuals (n = 6) at puberty (7.24 ± 0.39 months) and sexual maturity (10 ± 0.40 months) were compared, identifying molecular signatures associated with reproductive development. Total RNA sequencing (Illumina NovaSeq-6000) and miRNA sequencing (Illumina NextSeq-500) were performed on all 12 paired samples (6 boars at 2 time points), followed by differential expression analysis using a paired statistical model in DESeq2 to account for repeated measures. - Source: PubMed
Publication date: 2026/01/21
Shrestha Asmitavan Son MarenHashim AdnanRouzbehani SoudabehGilfillan Gregor DBerge UrszulaKommisrud ElisabethAlm-Kristiansen Anne Hege - - Source: PubMed
Liu XiaoliChen BonanXie FudaWong Kit YeeCheung Alvin H KZhang JinglinWu QianFang CanbinHu JintaoWang ShouyuXu DazhiChen JianwuWang YuzhiWong Chi ChunChen HuarongWu William K KYu JunChan Michael W YTsang Chi ManLo Kwok WaiTse Gary M KTo Ka-FaiKang Wei - Colorectal cancer (CRC) poses a threat to the health of people worldwide. Long noncoding RNAs (lncRNAs) have been reported to play a key role in regulating carcinogenesis, including CRC. In this study, the levels of lncRNA FOXP4-AS1 were analyzed in CRC specimens and cells via qRT-PCR. The impacts of FOXP4-AS1 on CRC cell metastasis were investigated. Then, the silver staining assay, western blot, RIP, Co-IP, and immunofluorescence were conducted to explore and validate the molecular mechanisms by which FOXP4-AS1 affects CRC progression. We discovered that FOXP4-AS1 expression was markedly elevated in CRC. Functionally, FOXP4-AS1 knockdown suppressed CRC cell migration, invasion, and EMT. Also, FOXP4-AS1 silencing weakened CRC tumor growth in vivo. Mechanistically, we identified that FOXP4-AS1 functioned as a scaffold to simultaneously bind USP7 and ZEB1, and regulated the ubiquitination and expression of ZEB1 by binding to USP7. Rescue experiments demonstrated that USP7 inhibitor P005091 abolished the promotion of cell metastasis by FOXP4-AS1 overexpression. Furthermore, ZEB1 overexpression reversed the impact of silencing FOXP4-AS1 on cell metastasis. Collectively, our work revealed the molecular mechanism and role of FOXP4-AS1-mediated USP7-ZEB1 axis in CRC. - Source: PubMed
Publication date: 2026/01/04
Yang XiaolingShen ChenglongYuan YuchenShao JiazheLiu HaichenLi YichenZhou GuoqiangShi Zhiliang - - Source: PubMed
Publication date: 2025/10/15