CDX4 antibody - middle region (ARP31478_P050)
- Known as:
- CDX4 (anti-) - middle region (ARP31478_P050)
- Catalog number:
- arp31478_p050
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Aviva Systems Biology
- Gene target:
- CDX4 antibody - middle region (ARP31478_P050)
Related genes to: CDX4 antibody - middle region (ARP31478_P050)
- Gene:
- CDX4 NIH gene
- Name:
- caudal type homeobox 4
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- Xq13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1995-06-14
- Date modifiied:
- 2014-11-18
Related products to: CDX4 antibody - middle region (ARP31478_P050)
Related articles to: CDX4 antibody - middle region (ARP31478_P050)
- Two new three-dimensional organic-inorganic hybrid crystalline materials, [(Ade) CdCl] () and [(Ade) CdBr] (), were obtained by the slow evaporation of adenine (Ade) and cadmium chloride in aqueous solution at room temperature with hydrochloric acid and hydrobromic acid used as halogen sources. The structural, thermal, optical, and electrical properties were characterized by single-crystal X-ray diffraction, infrared spectroscopy, thermogravimetric analysis, variable-temperature-variable-frequency dielectric constant analysis, and electrochemical tests. With increasing the substitution of Cl by Br, the composition of the material changed and the space group shifted from -1 to 2/m, with a significant blue-shift in the fluorescence emission. Changing the temperature induced the deformation of the three-dimensional framework structure formed by hydrogen bonding interactions, leading to dielectric anomalies. Cyclic voltammetry tests showed the good reversibility of the electrolysis process. The structural diversity of the complexes was realized by modulating the halogen composition, and a new method for designing novel organic-inorganic hybrids with controllable photoelectric functionality was proposed. - Source: PubMed
Publication date: 2024/06/11
Lv MeixiaHu HongzhiAdila AbuduheniYan YiboLiu YangLiu Zunqi - Acute Erythroid Leukemia (AEL) is a rare and aggressive subtype of Acute Myeloid Leukemia (AML). In 2022, the World Health Organization (WHO) defined AEL as a biopsy with ≥30% proerythroblasts and erythroid precursors that account for ≥80% of cellularity. The International Consensus Classification refers to this neoplasm as "AML with mutated ". Classification entails ≥20% blasts in blood or bone marrow biopsy and a somatic mutation (VAF > 10%). This type of leukemia is typically associated with biallelic mutations and a complex karyotype, specifically 5q and 7q deletions. Transgenic mouse models have implicated several molecules in the pathogenesis of AEL, including transcriptional master regulator GATA1 (involved in erythroid differentiation), master oncogenes, and CDX4. Recent studies have also characterized AEL by epigenetic regulator mutations and transcriptome subgroups. AEL patients have overall poor clinical outcomes, mostly related to their poor response to the standard therapies, which include hypomethylating agents and intensive chemotherapy. Allogeneic bone marrow transplantation (AlloBMT) is the only potentially curative approach but requires deep remission, which is very challenging for these patients. Age, AlloBMT, and a history of antecedent myeloid neoplasms further affect the outcomes of these patients. In this review, we will summarize the diagnostic criteria of AEL, review the current insights into the biology of AEL, and describe the treatment options and outcomes of patients with this disease. - Source: PubMed
Publication date: 2024/06/06
Fernandes PriyankaWaldron NatalieChatzilygeroudi TheodoraNaji Nour SabihaKarantanos Theodoros - Improving the egg production of goose is a crucial goal of breeding, because genetics is the key factor affecting egg production. Thus, we sequenced the genomes of 55 Chinese indigenous geese from six breeds, which were divided into the high egg-laying group (ZE, HY, and SC) and low egg-laying group (ZD, LH, and ST). Based on the results of the inter-population selection signal analysis, we mined the selected genome regions in the high egg-laying germplasm population to identify the key candidate genes affecting the egg-laying traits. - Source: PubMed
Publication date: 2023/12/06
Zhao HongchangSun GuoboMu XiaohuiLi XiaomingWang JunZhao MengliZhang GanshengJi RongchaoChen ChaoGao GuangliangWang Jian - Three novel heterometallic Ni/Cd coordination compounds [Ni(en)][CdCl]∙3dmso (), [Ni(en)(dmf)][CdBr] (), and [Ni(en)][CdI](I) () have been synthesized through the self-assembly process in a one-pot reaction of cadmium oxide, nickel salt (or nickel powder), NHX (X = Cl, Br, I), and ethylenediamine in non-aqueous solvents dmso (for ) or dmf (for and ). Formation of the one- () or three-dimensional ( and ) hydrogen-bonded frameworks has been observed depending on the nature of the [CdX] counter-anion, as well as on the nature of the solvent. The electronic structures of [Ni(en)] and [Ni(en)(dmf)] cations were studied at the DFT and CASSCF levels, including the ab initio ligand field theory (AILFT) calculations. The non-covalent intermolecular contacts between the cationic nickel and anionic cadmium blocks in the solid state were investigated by the QTAIM analysis. The mechanism of ligand substitution at the nickel center in [Ni(en)(dmf)] was theoretically investigated at the ωB97X-D4/ma-def2-TZVP//DLPNO-CCSD(T)/ma-def2-TZVPP level. The results demonstrate that thermodynamic factors are structure-determining ones due to low energy barriers of the rotation of dmf ligands in [Ni(en)(dmf)] (below 3 kcal mol) and the reversible transformation of [Ni(en)(dmf)] into [Ni(en)] (below 20 kcal mol). - Source: PubMed
Publication date: 2023/11/18
Nesterova Oksana VPetrusenko Svitlana RSkelton Brian WNesterov Dmytro S - Sonic hedgehog (Shh) signaling is the morphogen signaling that regulates embryonic craniofacial and neural tube development. G protein-coupled receptor 161 (Gpr161) is a negative regulator of Shh signaling, and its inactivation in mice results in embryo lethality associated with craniofacial defects and neural tube defects. However, the structural defects of later embryonic stages and cell lineages underlying abnormalities have not been well characterized due to the limited lifespan of Gpr161 null mice. We found that embryos with Pax3 lineage-specific deletion of Gpr161 presented with tectal hypertrophy (anterior dorsal neuroepithelium), cranial vault and facial bone hypoplasia (cranial neural crest), vertebral abnormalities (somite) and the closed form of spina bifida (posterior dorsal neuroepithelium). In particular, the closed form of spina bifida was partly due to reduced Pax3 and Cdx4 gene expression in the posterior dorsal neural tubes of Gpr161 mutant embryos with decreased Wnt signaling, whereas Shh signaling was increased. We describe a previously unreported role for Gpr161 in the development of posterior neural tubes and confirm its role in cranial neural crest- and somite-derived skeletogenesis and midbrain morphogenesis in mice. - Source: PubMed
Publication date: 2023/11/28
Kim Sung-EunChothani Pooja JShaik RehanaPollard WestleyFinnell Richard H