SUPT3H antibody - N-terminal region (ARP30038_T100)
- Known as:
- SUPT3H (anti-) - N-terminal region (ARP30038_T100)
- Catalog number:
- arp30038_t100
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Aviva Systems Biology
- Gene target:
- SUPT3H antibody - N-terminal region (ARP30038_T100)
Related genes to: SUPT3H antibody - N-terminal region (ARP30038_T100)
- Gene:
- SUPT3H NIH gene
- Name:
- SPT3 homolog, SAGA and STAGA complex component
- Previous symbol:
- -
- Synonyms:
- SPT3, SPT3L
- Chromosome:
- 6p21.1
- Locus Type:
- gene with protein product
- Date approved:
- 1998-10-09
- Date modifiied:
- 2016-10-05
Related products to: SUPT3H antibody - N-terminal region (ARP30038_T100)
Related articles to: SUPT3H antibody - N-terminal region (ARP30038_T100)
- Among the disorders of sex development (DSD) with karyotype 46,XY, there is a group of diseases caused by defects of androgen synthesis. The last stage of in the synthesis of androgens is the conversion of testosterone into a more active androgen dihydrotestosterone, which occurs under the influence of the enzyme 5α-reductase type II (SRD5A2). SRD5A2 deficiency is a rare disease with autosomal recessive inheritance. - Source: PubMed
Publication date: 2025/12/02
Kalinchenko N YMakretskaya N AKolodkina A AKareva M ATiulpakov A N - Air pollution is associated with Alzheimer's disease (AD), and the susceptibility of AD from air pollution may be affected by genetic characteristics, but the underlying mechanisms remain unknown. - Source: PubMed
Publication date: 2026/01/23
Ran ShanshanZhang JingyiCai MiaoChen LanQian ZhengminTian FeiWu GanBoyd Ri'ennaMcMillin Stephen EdwardZeng Huai-CaiYang YinLin Hualiang - Liver hepatocellular carcinoma (LIHC) is the most prevalent liver malignancy, often diagnosed at advanced stages, and resulting in a poor prognosis for patients. Ubiquitin-specific peptidase 22 (USP22) belongs to the ubiquitin-specific processing proteases (USPs) subfamily and has been identified as a gene signature associated with various cancer types in previous studies. However, the exact role of USP22 in LIHC remains to be fully elucidated. - Source: PubMed
Publication date: 2025/07/15
Xu KeminLu Yanjun - The Korean Sapsaree dog is a native breed known for its distinctive appearance and historical significance in Korean culture. The accurate estimation of breeding values is essential for the genetic improvement and conservation of such indigenous breeds. This study aimed to evaluate the accuracy of breeding values for body height, body length, chest width, hair length, and distraction index (DI) traits in Korean Sapsaree dogs. Additionally, a genome-wide association study (GWAS) was conducted to identify the genomic regions and nearby candidate genes influencing these traits. Phenotypic data were collected from 378 Korean Sapsaree dogs, and of these, 234 individuals were genotyped using the 170k Illumina CanineHD BeadChip. The accuracy of genomic predictions was evaluated using the traditional BLUP method with phenotypes only on genotyped animals (PBLUP-G), another traditional BLUP method using a pedigree-based relationship matrix (PBLUP) for all individuals, a GBLUP method based on a genomic relationship matrix, and a single-step GBLUP (ssGBLUP) method. Heritability estimates for body height, body length, chest width, hair length, and DI were 0.45, 0.39, 0.32, 0.55, and 0.50, respectively. Accuracy values varied across methods, with ranges of 0.22 to 0.31 for PBLUP-G, 0.30 to 0.57 for PBLUP, 0.31 to 0.54 for GBLUP, and 0.39 to 0.67 for ssGBLUP. Through GWAS, 194 genome-wide significant SNPs associated with studied Sapsaree traits were identified. The selection of the most promising candidate genes was based on gene ontology (GO) terms and functions previously identified to influence traits. Notable genes included CCKAR and DCAF16 for body height, PDZRN3 and CNTN1 for body length, TRIM63, KDELR2, and SUPT3H for chest width, RSPO2, EIF3E, PKHD1L1, TRPS1, and EXT1 for hair length, and DDHD1, BMP4, SEMA3C, and FOXP1 for the DI. These findings suggest that significant QTL, combined with functional candidate genes, can be leveraged to improve the genetic quality of the Sapsaree population. This study provides a foundation for more effective breeding strategies aimed at preserving and enhancing the unique traits of this Korean dog breed. - Source: PubMed
Publication date: 2024/11/21
Haque Md AzizulKim Na-KuangYeji RyuLee BugeunHa Ji-HongLee Yun-MiKim Jong-Joo - - Source: PubMed
Publication date: 2024/01/12
Germans Sharon KoorseChen Weina