Polyclonal Rabbit CDC73 Antibody
- Known as:
- Polyclonal Rabbit CDC73 Antibody
- Catalog number:
- abx000790
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Abbexa
- Gene target:
- Polyclonal Rabbit CDC73 Antibody
Related genes to: Polyclonal Rabbit CDC73 Antibody
- Gene:
- CDC73 NIH gene
- Name:
- cell division cycle 73
- Previous symbol:
- C1orf28, HRPT2, HRPT1
- Synonyms:
- parafibromin, FIHP
- Chromosome:
- 1q31.2
- Locus Type:
- gene with protein product
- Date approved:
- 2001-10-08
- Date modifiied:
- 2019-04-23
Related products to: Polyclonal Rabbit CDC73 Antibody
Related articles to: Polyclonal Rabbit CDC73 Antibody
- Endoscopically assisted surgery for parathyroid tumors has provided excellent cosmetic results and has been covered by Japan's national insurance system since 2016. However, careful handling is essential because parathyroid tumor cells can easily disseminate. - Source: PubMed
Publication date: 2026/05/12
Omi YokoYamanashi YukiNakai TomoyoshiYanagida JuroYoshida YusakuIto NaokoYamamoto TomokoNagashima YojiHoriuchi Kiyomi - Wilms tumor (WT), the most common kidney neoplasm in children, is closely associated with hereditary factors. This study included 134 WT patients (62 males, median age of 7 years, age at diagnosis of 24.9 months) with unilateral ( = 90, 67%) or bilateral WT ( = 44, 33%). Genetic testing was performed using targeted sequencing of 415 genes and multiplex ligation-dependent probe amplification (MLPA). Twenty-five mutations in eight genes were found in 17% ( = 23) of patients: ( = 10), ( = 4), ( = 3), ( = 3), ( = 2), ( = 1), ( = 1), and ( = 1). Large deletions of the 11p13 region were revealed in 6% ( = 5) of patients. The 11p15 locus methylation was studied in blood, tumor, and healthy kidney tissue of nine patients suspected of Beckwith-Wiedemann syndrome (BWS) using methylation-sensitive MLPA (MS-MLPA). BWS was diagnosed in 3% ( = 4) of cases (one patient had mosaic disease). Thus, genetic and epigenetic aberrations were identified in 32 WT patients (24%). These patients had a higher frequency of bilateral WT and a higher rate of abnormalities compared to patients without aberrations (56% vs. 25%, = 0.002; and 86% vs. 25%, < 0.0001, respectively). The detection of WT hereditary predisposing factors is crucial for treatment strategies and long-term patient surveillance. - Source: PubMed
Publication date: 2026/05/01
Semenova VeraSagoyan GarikZhukovskaya ElenaKozlova ValentinaGegelia NinaMitrofanova AnnaSuleymanova AminaDruy AlexanderZelenova EkaterinaPavlov VladislavRubanskay MarinaKarelin AlexanderVarfolomeeva SvetlanaNasedkina Tatiana - Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an uncommon autosomal dominant disorder associated with primary hyperparathyroidism due to parathyroid adenomas and ossifying jaw tumors. We present the case of a 31-year-old male who was incidentally diagnosed with severe parathyroid hormone-dependent hypercalcemia following a traumatic upper limb fracture. Subsequent evaluation confirmed the diagnosis of HPT-JT syndrome. Early recognition, prompt surgical management, and genetic confirmation are essential to ensure appropriate treatment and prevent long-term complications. - Source: PubMed
Publication date: 2026/03/16
Gupta KunalAsirvatham Adlyne ReenaMahadevan ShriraamSundaram SandhyaKumar DoraiCunnigaiper Narayanan - Poorly differentiated endometrial carcinoma in Black African women is under-characterized at the transcriptomic level, although it is known for aggressive subtypes. We conducted the first RNA-seq analysis of formalin-fixed, paraffin-embedded (FFPE) tumors from Black South African women to explore population-specific gene expression, alternative splicing, and novel isoforms. - Source: PubMed
Publication date: 2026/03/24
Molefi ThuloAlaouna MohammedChipiti TalentSebitloane HannahDlamini Zodwa - Primary hyperparathyroidism (PHPT) is most commonly caused by sporadic parathyroid adenomas, although 10% of cases have an underlying genetic condition which is important to diagnose to facilitate appropriate long-term follow-up, and personal and family screening. - Source: PubMed
Publication date: 2025/10/25
Wong MimiPillai SoorajCiin Louise C H