CDC25C (phospho-Ser216) Antibody
- Known as:
- CDC25C (phosphorilated-Ser216) Antibody
- Catalog number:
- abx000371
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Abbexa
- Gene target:
- CDC25C (phospho-Ser216) Antibody
Related genes to: CDC25C (phospho-Ser216) Antibody
- Gene:
- CDC25C NIH gene
- Name:
- cell division cycle 25C
- Previous symbol:
- CDC25
- Synonyms:
- PPP1R60
- Chromosome:
- 5q31.2
- Locus Type:
- gene with protein product
- Date approved:
- 1992-02-06
- Date modifiied:
- 2017-12-06
Related products to: CDC25C (phospho-Ser216) Antibody
Related articles to: CDC25C (phospho-Ser216) Antibody
- Oral squamous cell carcinoma (OSCC) remains a substantial global health burden. According to the latest global cancer statistics, it accounts for an estimated 300,000 new cases and 100,000 deaths annually. This study aimed to investigate the pharmacological effects of digitoxin, a cardenolide glycoside, on the modulation of proliferative capacity and apoptotic induction in human OSCC human tongue squamous carcinoma (HSC-3) cells. - Source: PubMed
Publication date: 2026/03/23
Rui YingWang YanGong HongfeiZhu XuanyuXu QingLin JingWei Jingchen - Sinonasal inverted papilloma is a locally aggressive epithelial lesion with a relatively high recurrence rate, yet the molecular basis of its proliferative behaviour remains incompletely understood. This study investigated the clinical relevance of secreted phosphoprotein 1 in sinonasal inverted papilloma and its association with epithelial cell proliferation and related signalling pathways. - Source: PubMed
Publication date: 2026/04/28
Tang WenruiWang LinYan XudongZhang JishengYu LonggangChen HanZheng ChungeDong ZihuiZheng QianyouHan LinJiang Yan - Polyethylene terephthalate (PET), one of the most widely used synthetic polymers globally, has emerged as a potential environmental risk factor for human health. However, the molecular mechanisms linking PET exposure to hepatocellular carcinoma (HCC) remain poorly understood. - Source: PubMed
Publication date: 2026/04/22
Chen PengLiu XinYuan DongmeiZheng LanDu YuminGong DacaiWei XingWang DanXu GeGe Bin - Subsequently to the publication of the above article, a concerned reader drew to the Editor's attention that the β‑actin bands featured in Fig. 1A were also apparently included in the 'Ctrl' experiments for the phospho‑P53 protein bands in Fig. 1B. In addition, a specific pair of P53 bands in Fig. 1B had also apparently been re‑used as phospho‑CDC25C bands in Fig. 6A, suggesting that these figures may have potentially undergone inappropriate editing. After having evaluated these data independently in the Editorial Office, the concerns of the reader were shown to have been well‑founded. Therefore, in view of the uncertainties regarding the assembly of some of the western blot data in Figs. 1 and 6, the Editor of has decided that this paper should be retracted from the Journal on account of uncertainties with the presentation of the abovementioned data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply.The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 35: 2707‑2714, 2016; DOI: 10.3892/or.2016.4674]. - Source: PubMed
Publication date: 2026/04/30
Zhang RuopengZhu LiZhang LirongXu AnliLi ZhengweiXu YijuanHe PeiWu MaoqingWei FengxiangWang Chenhong - Benzo(a)pyrene (BaP), an environmental carcinogen, contributes to colon cancer pathogenesis through incompletely elucidated mechanisms. This study integrated network toxicology and multi-omics analyses to decipher BaP-associated molecular signatures and clinical relevance in colon cancer. Using TCGA-COAD data, 113 differentially expressed BaP-related targets were identified via CTD and Super-PRED databases. PPI networks, functional enrichment, and Cox/Lasso regression revealed key pathways (xenobiotic metabolism, p53 signaling, cell cycle) and six prognostic genes (CLK2, CRYAB, RPS6KA1, DPP7, CDC25C, GAST). A BaP-related risk model stratified patients into distinct survival groups. A nomogram accurately predicted 1-, 3-, and 5-year overall survival. High-risk scores correlated with advanced tumor stage, metastasis, and immunosuppressive microenvironments. Molecular docking demonstrated strong BaP binding to CLK2 and CRYAB. External validation (GSE39582, TNMplot) confirmed tumor-specific gene expression patterns. These findings delineate BaP-driven networks connecting xenobiotic stress, immune dysregulation, and tumor progression. The risk model provides a prognostic biomarker for personalized management and therapeutic targeting in colon cancer. - Source: PubMed
Publication date: 2026/04/22
Yang XueyingYang ZhendongSui Bowen