GSK3A (phospho-Ser21) Antibody
- Known as:
- GSK3A (phosphorilated-Ser21) Antibody
- Catalog number:
- abx000172
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Abbexa
- Gene target:
- GSK3A (phospho-Ser21) Antibody
Related genes to: GSK3A (phospho-Ser21) Antibody
- Gene:
- GSK3A NIH gene
- Name:
- glycogen synthase kinase 3 alpha
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 19q13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1997-05-15
- Date modifiied:
- 2016-10-05
Related products to: GSK3A (phospho-Ser21) Antibody
Related articles to: GSK3A (phospho-Ser21) Antibody
- Atherosclerosis (AS) is a leading cardiovascular disease driven by lipid metabolism dysregulation and immune maladaptation. Although macrophage autophagy modulates plaque stability, the specific autophagy-related genes governing AS progression, particularly in spatial and immune contexts, remain poorly defined. This study aimed to systematically identify and characterize key macrophage autophagy-associated genes in AS using an integrated multi-omics approach. - Source: PubMed
Publication date: 2026/02/26
Cao WenqiWang BingyangWang YuxueLi YunyanYang HanningSun YueXu LirongLu Yongping - Organoids derived from pluripotent stem cells have emerged as powerful models to study human development. To investigate signaling pathways regulating human pancreas differentiation and morphogenesis, we developed a high-content, image-based screen and quantitative multivariate analysis pipelines robust to heterogeneity to extract single-cell and organoid features using pancreatic progenitor organoids. Here, we identified 54 compounds affecting cell identity and/or morphological landscape. Focusing on one family of compounds, we found that glycogen synthase kinase 3α/β (GSK3A/B) inhibition via wingless/int-1 (WNT) signaling has a reversible effect on cell identity, repressing pancreatic progenitor markers and inducing a poised state in progenitors transitioning to acinar cells. We show that additional fibroblast growth factor (FGF) repression enables further differentiation of acinar cells, recapitulating pancreatic acinar morphogenesis and function. The ability to produce acinar cells is valuable for future studies on pancreatic exocrine function and cancer initiation in humans, as acinar cells are thought to be an important cell of origin for pancreatic adenocarcinoma. - Source: PubMed
Publication date: 2026/01/21
Keshara RashmiparvathiKuodyte KarolinaJanosch AntjeAndree CordulaBickle MarcStöter MartinBarsacchi RicoKim Yung HaeGrapin-Botton Anne - Right ventricular dysfunction (RVD) is a common complication of idiopathic dilated cardiomyopathy linked to poor outcomes. However, reliable noninvasive biomarkers for RVD remain lacking. This study aimed to identify urinary proteomic markers using mass spectrometry and machine learning. - Source: PubMed
Publication date: 2025/12/17
Wu AnhuWang YufeiGuo ZhengguangYu JiaqiMei KeyiZhang JingQin XiaohanQin YuhanGuo Xiaoxiao - Lung adenocarcinoma (LUAD) has a high mortality rate. The signaling of endoplasmic reticulum (ER) stress sensor can regulate cancer progression. We aimed to investigate the relationship between ER stress-related genes and LUAD prognosis. - Source: PubMed
Publication date: 2025/12/13
Tang MingmingZhang ShiZhou XingniCai Zhigang - Endometrial cancer (EC) is one of the most common gynecological malignancies globally. Increasing attention has been paid to the role of environmental pollutants in EC development. Epidemiological studies have demonstrated a significant association between elevated urinary concentrations of bis(1,3-dichloro-2-propyl) phosphate (BDCPP) and an increased risk of EC. However, the hub genes and underlying mechanisms of BDCPP-induced EC remain poorly understood. - Source: PubMed
Publication date: 2025/09/23
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