HIST1H3B (phospho-Thr12) Antibody
- Known as:
- HIST1H3B (phosphorilated-Thr12) Antibody
- Catalog number:
- abx000163
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Abbexa
- Gene target:
- HIST1H3B (phospho-Thr12) Antibody
Related genes to: HIST1H3B (phospho-Thr12) Antibody
- Gene:
- HIST1H3B NIH gene
- Name:
- histone cluster 1 H3 family member b
- Previous symbol:
- H3FL
- Synonyms:
- H3/l
- Chromosome:
- 6p22.2
- Locus Type:
- gene with protein product
- Date approved:
- 1998-08-27
- Date modifiied:
- 2016-08-15
Related products to: HIST1H3B (phospho-Thr12) Antibody
Related articles to: HIST1H3B (phospho-Thr12) Antibody
- Accurate glioma diagnosis relies on tissue biopsy, which is often challenging. Liquid biopsy offers an alternative, but single-component circulating free DNA (cfDNA) or circulating free RNA (cfRNA) approaches have limited comprehensiveness. We developed and validated GlioKit, a platform for simultaneous cfDNA and cfRNA extraction from cerebrospinal fluid (CSF) to enhance diagnostic coverage, and evaluated its accuracy by correlating CSF-derived molecular profiles with tumor characteristics. - Source: PubMed
Publication date: 2026/02/16
Sun MaoyuanJiang ShanXu HoushiZeng YulaiLiu BeiningWang YueLi ZhenGuan YunChen JiawenZhu RuizePing WeiqiuTeng YanlinYan SonglinLiu LiyingShen DanTang QishengFan ZhenNg Ho-KeungQin ZhiyongMao YingShi Zhifeng - Rare pediatric subdural tumors can mimic subdural hematomas and can be caused by lymphoma, sarcoma, and cancer metastases. - Source: PubMed
Publication date: 2026/02/02
Ishikawa TakaakiTsurubuchi TakaoNagatomo KumieHosaka ShoFukushima HirokoSakamoto NoriakiHirato JunkoInoue YoheiIchimura KoichiMizumoto MasashiMuroi AiTakada HidetoshiIshikawa Eiichi - Although natural killer (NK) cells play crucial roles in the immune response to () infection, systematic investigations delineating the immune characteristics of NK cells across the tuberculosis (TB) disease spectrum are scarce. - Source: PubMed
Publication date: 2025/06/16
Zhang HanLiu LiguoHu JieWu XiaolinZheng JianhuaXin HenanDu JiangYang JiarongLv ZizhengWu ZhuoranGao LeiLiu RongmeiSun HaidanZhang XiaobingJin Qi - The malignant transformation of odontogenic keratocysts (OKC) into cancerous odontogenic keratocysts (COKC) is exceedingly rare, and its mechanisms remain poorly understood. Studies exploring the cellular heterogeneity, molecular pathways, and clinical features of COKC are limited. In this study, we performed single-cell RNA sequencing (scRNA-seq) on three COKC samples and integrated the data with a public OKC dataset, identifying 22,509 single cells. Two COKC-specific epithelial subpopulations, Basal-C0-EXT1 and Basal-C3-HIST1H3B, were identified. These subpopulations exhibited enhanced stemness and invasive potential, respectively, suggesting their roles as key drivers of OKC carcinogenesis. Fibroblasts underwent phenotypic transitions, particularly from inflammation-associated fibroblasts (IFBs) to myofibroblasts (MFBs). Similarly, macrophage phenotypic transformation may also play a role in OKC carcinogenesis. Clinical observations of severe lesion-area pain in COKC patients suggest potential neuroinvasiveness, Supported by single-cell transcriptomic data, imaging findings, and histopathological evidence. A review of clinical data revealed that none of the COKC patients exhibited cervical lymph node metastasis. Single-cell transcriptomics suggests that this phenomenon may be associated with an active immune microenvironment in COKC, reduced epithelial-mesenchymal transition (EMT) activity, lower VEGFC expression, and upregulated MAST4 expression as a potential regulator of lymphatic metastasis. In conclusion, COKC exhibits distinct molecular, cellular, and clinical characteristics compared to OKC, featuring potent neuroinvasiveness and low lymph node metastatic potential. These findings provide important insights into the mechanisms underlying COKC development and may guide novel diagnostic and therapeutic strategies. - Source: PubMed
Publication date: 2025/03/18
Zhao GuileLi YikeLi HonglingBao MingzheLubamba Grace PakaWang GuanruHan BoTang YalingLi TaiwenLi Chunjie - Glioblastoma (GB) is known for its highly invasive nature. Images of butterfly GB (bGB) often illustrate this characteristic, but the molecular background and origins of bGB remain unknown. - Source: PubMed
Publication date: 2024/10/23
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