ACAA1 293T Cell Transient Overexpression Lysate(Denatured)
- Known as:
- ACAA1 293T Cell Transient Overexpression Lysate(Denatured)
- Catalog number:
- H00000030-T01
- Product Quantity:
- 100 uL
- Category:
- -
- Supplier:
- Abno
- Gene target:
- ACAA1 293T Cell Transient Overexpression Lysate(Denatured)
Related genes to: ACAA1 293T Cell Transient Overexpression Lysate(Denatured)
- Gene:
- ACAA1 NIH gene
- Name:
- acetyl-CoA acyltransferase 1
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 3p22.2
- Locus Type:
- gene with protein product
- Date approved:
- 1989-06-30
- Date modifiied:
- 2019-03-22
Related products to: ACAA1 293T Cell Transient Overexpression Lysate(Denatured)
Related articles to: ACAA1 293T Cell Transient Overexpression Lysate(Denatured)
- Prior use of spent hemp biomass (SHB), a byproduct of cannabidiol extraction, has shown promise as a low-cost livestock feed in ruminant diets. However, due to concerns over residual cannabinoids in carcass tissues, it has not been approved by the FDA-CVM for livestock use. Moreover, research on SHB effects in monogastrics remains scarce. The objective of this study was to examine varying levels of dietary SHB inclusion in broiler diets and their effects on performance, meat quality, expression of genes in adipose tissue, and stress. Two hundred (n=200) 5-day-old Cobb-500 chicks were randomly assigned to corn-soybean-based diets containing 0%, 5%, 10%, or 20% SHB for a 42-day feeding trial (5 pens/group). Diets were isocaloric, isonitrogenous, and balanced for fiber. At the end of the experiment, birds were euthanized and sexed, with two males and two females selected from each pen (n=80) for subsequent sampling. Feed intake was not adversely affected by SHB supplementation; however, inclusion at ≥10% negatively impacted feed conversion rate and body weight, while pasty vent was higher in all SHB treatments than in the control. Dietary SHB at ≥10% level decreased growth and breast weight. SHB at 20% level increased breast yellowness (b*), drip loss (vs. lower SHB doses), and shear force (i.e., lower tenderness). Feeding 20% SHB decreased triglycerides, total fatty acids, and the proportion of unsaturated fatty acids in muscle (vs. lower SHB doses), while increasing the proportion of cholesterogenic and bacteria-derived fatty acids (vs. lower SHB doses), suggesting SHB affects lipid synthesis and utilization. This was confirmed by the increase in transcription of genes involved in fat catabolism, ACAA1 and ACOX, in the abdominal adipose tissue, specifically for males. Birds receiving 20% SHB also had higher corticosterone in the feathers, indicating possibly higher chronic stress. Overall, dietary SHB inclusion at levels ≥10% negatively affected broiler performance, meat quality, lipid metabolism, and corticosterone in feathers (as a chronic stress indicator), whereas inclusion at 5% did not produce adverse effects. These results indicate that low levels of SHB may be incorporated into broiler diets without compromising bird health or productivity, although higher inclusion rates appear detrimental. - Source: PubMed
Publication date: 2026/08/28
Parker Nathan BHermes JamesIrawan AgungPearce CarolynFerschweiler DresenAtes SerkanBionaz Massimo - The purpose of the study was to evaluate the anterior communicating artery (ACoA) patency in patients with suboptimal temporal bone windows who were scheduled for carotid endarterectomy (CEA), using contrast-enhanced transcranial color-coded real-time sonography (CE-TCCS) combined with common carotid artery compression (CCC) test. - Source: PubMed
Publication date: 2026/09/01
Liu YingZheng ShuaiGan YuyangWang SenHe WenZhang Wei - Lung cancer (LC) and venous thromboembolism (VTE) are closely associated, with VTE contributing to morbidity and mortality among patients with LC. We aimed to identify and characterize a mitochondrial-related transcriptomic signature shared between LC and VTE and to explore its association with immune microenvironment features. - Source: PubMed
Publication date: 2026/09/04
Zhang Xue LiGao Ai LiLiu Zhan Ju - Hickory nuts were nutrient-rich but were prone to storage deterioration due to high fat content. In this study, using integrated lipidomics and transcriptomics, we profiled 2159 lipids and 5952 differentially expressed genes in hickories stored at 4 °C and 35 °C for 90 days. Results showed that oxidative stress decreased iodine value and increased anisidine and conjugated diene values, reflecting reduced lipid unsaturation and oxidation product accumulation. Upregulation of TGL4 and PLD1_2 accelerated triglyceride and phospholipid hydrolysis. However, ACAA1 downregulation inhibited free fatty acid catabolism generated during this process, which promoted off-flavor generation and anomalous triglyceride accumulation via re-esterification. Additionally, downregulation of DGKs and FAB2 caused the gradual accumulation of LPCs and Cer, disrupting sphingolipid balance and membrane integrity. This multi-omics study elucidates how dysregulation of lipid repair and sphingolipid disruption lead to accelerated oxidation during hickory storage. The findings supported Sustainable Development Goal 12.3 by informing strategies to reduce postharvest nut losses. - Source: PubMed
Publication date: 2026/08/29
Wang ChongchongBi YajunMin Weihong - The lenticulostriate arteries (LSAs) demonstrate developmental variability that is linked to the A1 segment of the anterior cerebral artery (ACA) anatomy. In acute ischaemic stroke (AIS) with MCA occlusion, basal ganglia (BG) infarction extent and haemorrhagic transformation (HT) correlate with LSA involvement. This study aimed to assess whether ipsilateral A1-ACA variations influence BG infarction severity and thrombectomy outcomes. - Source: PubMed
Sun WenpingHe GuangchenLu HaitaoWei LimingXu HaoyangZhu Yueqi