Cymax Human IL-8 ELISA Kit
- Known as:
- Cymax Human Interleukin-8 Enzyme-linked immunosorbent assay test Kit
- Catalog number:
- lf-ek0262
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Abfrontier
- Gene target:
- Cymax Human IL-8 ELISA Kit
Related genes to: Cymax Human IL-8 ELISA Kit
- Gene:
- CXCL8 NIH gene
- Name:
- C-X-C motif chemokine ligand 8
- Previous symbol:
- IL8
- Synonyms:
- SCYB8, LUCT, LECT, MDNCF, TSG-1, IL-8, NAP-1, 3-10C, MONAP, AMCF-I, LYNAP, NAF, b-ENAP, GCP-1, K60, GCP1, NAP1
- Chromosome:
- 4q13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1989-06-30
- Date modifiied:
- 2016-10-05
- Gene:
- CXCR1 NIH gene
- Name:
- C-X-C motif chemokine receptor 1
- Previous symbol:
- CMKAR1, IL8RA
- Synonyms:
- CKR-1, CDw128a, CD181
- Chromosome:
- 2q35
- Locus Type:
- gene with protein product
- Date approved:
- 1992-11-09
- Date modifiied:
- 2016-03-14
- Gene:
- CXCR2 NIH gene
- Name:
- C-X-C motif chemokine receptor 2
- Previous symbol:
- IL8RB
- Synonyms:
- CMKAR2, CD182
- Chromosome:
- 2q35
- Locus Type:
- gene with protein product
- Date approved:
- 1991-08-19
- Date modifiied:
- 2016-03-14
- Gene:
- CXCR2P1 NIH gene
- Name:
- C-X-C motif chemokine receptor 2 pseudogene 1
- Previous symbol:
- IL8RBP, CXCR2P
- Synonyms:
- -
- Chromosome:
- 2q35
- Locus Type:
- pseudogene
- Date approved:
- 1992-11-27
- Date modifiied:
- 2016-03-14
Related products to: Cymax Human IL-8 ELISA Kit
Related articles to: Cymax Human IL-8 ELISA Kit
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Publication date: 2026/08/27
Ao WeiLi HaoranZhang YuhangWu ZhenhengYang HaoChen Zhigang - Follicular-cell-derived thyroid cancers that progress from differentiated tumors to poorly differentiated or anaplastic states commonly lose thyroid lineage identity, radioiodine avidity, and favorable clinical behavior. Genetic and signaling alterations within tumor cells explain part of this transition, but they do not fully account for the coexistence of different differentiation states within the same molecular subtype or even within the same lesion. Increasing functional evidence indicates that dedifferentiation is maintained by reciprocal interactions between malignant cells and the immune, stromal, metabolic, and inflammatory microenvironment. Cancer-associated fibroblast glycolysis and lactate release, IL-6/CXCL8-driven inflammatory signaling, hypoxia, transforming growth factor-beta signaling, and tumor-associated macrophage feedback can suppress thyroid lineage programs while promoting plasticity, invasion, and treatment resistance. Here, we synthesize mechanistic studies supported by genetic perturbation, co-culture, pharmacologic blockade, iodine-uptake assays, animal models, or patient-level radioiodine endpoints. We distinguish functional dedifferentiation from epithelial-mesenchymal transition, stemness, and lymph-node metastasis, and discuss therapeutic strategies that combine tumor-cell redifferentiation with targeting of microenvironmental feedback to restore durable radioiodine sensitivity. - Source: PubMed
Publication date: 2026/08/16
Ye QingYu Xiao-Ping - Children with autism spectrum disorder (ASD) exhibit gut mucosal immune alterations, but the co-regulatory architecture linking stool immune proteins and cytokines within the same cohort remains unstudied. In 115 children (74 ASD, 41 controls; age 5-18 years), seven stool immune proteins (IgA subclasses, α-antitrypsin and calprotectin subunits) were quantified by UHPLC-MS/MS and ten by Luminex-chemokines eotaxin/CCL11 and IL-8/CXCL8 plus eight cytokines-each normalised to total protein. Age-adjusted partial Spearman correlations were computed for all 70 protein-cytokine pairs per stratum, using Benjamini-Hochberg correction, bootstrap confidence intervals and Fisher r-to-z tests. No pair survived FDR correction in any stratum. IgA1 and IL-1β/TP correlated positively across all strata (full cohort ρ = 0.409, 95% CI 0.131-0.634, = 62; controls 0.583; ASD 0.210), with no significant between-group difference (Fisher z = 1.70, = 0.090). Multiple imputation attenuated this to ρ = 0.265 (95% CI 0.055-0.452). An inverse trend between IL-1β/TP and CARS score (ρ = -0.336, = 41) did not survive correction (-FDR = 0.576). This power-limited, hypothesis-generating study identifies an exploratory IgA1-IL-1β mucosal axis present across groups, with no confirmed between-group difference. Adequately powered multi-centre studies are required. - Source: PubMed
Publication date: 2026/08/07
Osredkar JoškoGodnov UrošVrhovšek Maja JekovecOsredkar DamjanAvguštin GorazdFabjan TejaKumer Kristina - Immune exclusion in head and neck squamous cell carcinoma (HNSCC) limits immunotherapy efficacy, yet the molecular determinants of stromal-immune organization remain incompletely characterized. The desmosomal cadherin DSG2 is highly expressed in squamous epithelium; its role in shaping the tumor microenvironment (TME) is unknown. - Source: PubMed
Publication date: 2026/08/13
Çiçek Ömer TarıkÇakır Muharrem OkanKurt BegümYılmaz Betül KarademirAshrafi G HosseinÖzdoğan Mustafa - This study aimed to (a) evaluate the effects of Acceptance and Commitment Therapy (ACT) and Behavioral Activation Therapy for Depression (BATD) on immune-inflammatory biomarkers in patients with chronic low back pain and comorbid depression, and (b) explore whether these biomarkers and genetic polymorphisms in BDNF and FKBP5 predict treatment response. - Source: PubMed
Publication date: 2026/08/27
Pérez-Aranda AdriánRodríguez-Freire CarlaSanabria-Mazo Juan PFeliu-Soler AlbertGrasa MarCarrillo AlbertEsteve MontserratFilluelo OrianaRosa AraceliColomer-Carbonell AriadnaMas-Bermejo PatriciaMcCracken Lance MBorràs XavierLuciano Juan V