PRDX1 (Human) Recombinant Protein (P01)
- Known as:
- PRDX1 (Human) Recombinant Protein (P01)
- Catalog number:
- H00005052-P01-25
- Product Quantity:
- 25 ug
- Category:
- -
- Supplier:
- Abno
- Gene target:
- PRDX1 (Human) Recombinant Protein (P01)
Related genes to: PRDX1 (Human) Recombinant Protein (P01)
- Gene:
- BZW2 NIH gene
- Name:
- basic leucine zipper and W2 domains 2
- Previous symbol:
- -
- Synonyms:
- HSPC028, MST017, MSTP017
- Chromosome:
- 7p21.1
- Locus Type:
- gene with protein product
- Date approved:
- 2002-08-05
- Date modifiied:
- 2016-10-05
- Gene:
- C2CD3 NIH gene
- Name:
- C2 calcium dependent domain containing 3
- Previous symbol:
- -
- Synonyms:
- DKFZP586P0123
- Chromosome:
- 11q13.4
- Locus Type:
- gene with protein product
- Date approved:
- 2007-10-17
- Date modifiied:
- 2016-06-08
- Gene:
- MBTD1 NIH gene
- Name:
- mbt domain containing 1
- Previous symbol:
- -
- Synonyms:
- SA49P01, FLJ20055
- Chromosome:
- 17q21.33
- Locus Type:
- gene with protein product
- Date approved:
- 2003-01-15
- Date modifiied:
- 2015-04-21
- Gene:
- PRDX1 NIH gene
- Name:
- peroxiredoxin 1
- Previous symbol:
- PAGA
- Synonyms:
- NKEFA
- Chromosome:
- 1p34.1
- Locus Type:
- gene with protein product
- Date approved:
- 1993-11-01
- Date modifiied:
- 2014-11-19
- Gene:
- TMEM63C NIH gene
- Name:
- transmembrane protein 63C
- Previous symbol:
- C14orf171
- Synonyms:
- DKFZp434P0111, CSC1, hsCSC1
- Chromosome:
- 14q24.3
- Locus Type:
- gene with protein product
- Date approved:
- 2003-12-10
- Date modifiied:
- 2017-10-17
Related products to: PRDX1 (Human) Recombinant Protein (P01)
Related articles to: PRDX1 (Human) Recombinant Protein (P01)
- Dark muscle in fish exhibits distinct nutritional, oxidative, and functional characteristics compared to ordinary muscle. This study aimed to elucidate the underlying biochemical variations of oxidative microenvironment in dark and ordinary muscles in snakehead fish (Channa argus) through multi-omics analyses. Dark muscle exhibited a stronger oxidative signature (higher TBARS and protein carbonyls, lower sulfhydryl content), and higher emulsifying activity/stability but lower buffering capacity, reduced foaming capacity and weaker gelation. Dark muscle contained higher levels of crude fat, protein, iron and glutathione, but lower moisture content and pH. Lipidomics revealed enrichment of mitochondria-associated lipid features, particularly cardiolipin and phosphatidylglycerol, together with glycolipids and highly unsaturated triglycerides; proteomics indicated higher abundance of proteins involved in oxidative phosphorylation, fatty-acid β-oxidation and redox/antioxidant defense (e.g., PRDX1, SOD2, MGST3); and metabolomics showed elevated PUFA-derived oxidation products, TCA-cycle intermediates and redox-related cofactors. By integrating lipidomic, proteomic, and metabolomic data, this study captures concordant changes in lipid composition, oxidative metabolism, and redox-related metabolites, thereby providing a more comprehensive explanation for the techno-functional between dark and ordinary muscles and showing that the oxidation-prone biochemical background of dark muscle is associated with enhanced emulsifying properties but reduced gel-forming ability. - Source: PubMed
Publication date: 2026/04/20
Yu QingqingBao YulongZhang LongtengHong HuiGao Ruichang - - Source: PubMed
Publication date: 2026/04/19
Škopková MartinaKabelíková PavlínaAndrésová AndreaBrennerová KatarínaDallemule SilviaSabo MiroslavPetrovič RóbertGašperíková Daniela - Keloids represent a pathological fibroproliferative disorder with high recurrence rates and limited therapeutic options. This study integrates multi-dataset transcriptomics (GSE158395, GSE188952, GSE92566, GSE173900) and machine learning algorithms (XGBoost, Random Forest, LASSO) to systematically investigate the role of lactylation modification in keloid pathogenesis. We identified 26 lactylation-related differentially expressed genes (15 upregulated, 11 downregulated) enriched in oxidative stress, immune response, and extracellular matrix pathways. Machine learning convergence revealed five lactylation hub genes (PRDX1, CSRP1, IFI16, CALD1, VIM), with PRDX1 exhibiting the highest diagnostic efficacy (AUC = 0.85). Immune infiltration analysis demonstrated significant correlations between hub genes and dysregulated immune cells. Experimental validation confirmed reduced PRDX1 expression in keloid tissues; its knockdown in fibroblasts elevated ROS levels and enhanced proliferation and migration. Regulatory network analysis predicted shared transcription factors (KLF12, NFKB1, MYC) governing hub genes, while drug screening prioritized three clinically actionable compounds (acetaminophen, valproic acid, vorinostat) targeting PRDX1. These findings establish lactylation as a critical regulator of keloid pathogenesis and identify PRDX1 as a promising therapeutic target. - Source: PubMed
Publication date: 2026/04/17
He RuizheSun MengzheLiu TiantianPeng YinboPeng LinboFang Yong - Acute liver injury (ALI) is a severe condition characterized by excessive hepatic inflammation and oxidative stress, yet effective therapeutic strategies remain limited. Dihydromyricetin (DMY), a natural flavonoid, possesses hepatoprotective properties, but the precise molecular mechanisms involving acetylation modifications underlying its effects are not fully understood. - Source: PubMed
Publication date: 2026/04/04
Hu HongWang ChenChen MengyanHan JinluSong YunChen ZikeZhao DeWang YugangYu HeguoShi Min - - Source: PubMed
Publication date: 2026/04/08
Lai WenjieZhu WeianWu JianjieHuang JiongduanLi XiaojuanLuo YunWang YuZeng HengdaLi MingqiangQiu XiaofuWen Xingqiao