Monkey acylated ghrelin (AG) ELISA kit
- Known as:
- Monkey acylated ghrelin (AG) Enzyme-linked immunosorbent assay test reagent
- Catalog number:
- e09a1308
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Blue gene shanghai
- Gene target:
- Monkey acylated ghrelin () ELISA kit
Related genes to: Monkey acylated ghrelin (AG) ELISA kit
- Gene:
- GHRL NIH gene
- Name:
- ghrelin and obestatin prepropeptide
- Previous symbol:
- -
- Synonyms:
- MTLRP, ghrelin, obestatin
- Chromosome:
- 3p25.3
- Locus Type:
- gene with protein product
- Date approved:
- 2006-01-05
- Date modifiied:
- 2016-08-10
Related products to: Monkey acylated ghrelin (AG) ELISA kit
Human ELC ELISA KIT 96 TEST
OxiSelect In Vitro ROS/RNS Assay Kit (Green Fluorescence), Trial Size
OxiSelect Methylglyoxal (MG) Competitive ELISA Kit
OxiSelect Methylglyoxal (MG) Competitive ELISA Kit
OxiSelect TBARS Assay Kit (MDA Quantitation), Trial Size
OxiSelect Total Antioxidant Capacity (TAC) Assay Kit, Trial Size
OxiSelect™ In Vitro ROS RNS Assay Kit (Green Fluorescence), Trial Size(1-3)-beta-D-glucan Sandwich ELISA, Double Antibody(1-Kit )11,12-EET DHET Immunoassay Kit(1-Kit )11,12-EET_DHET Immunoassay Kit(1-Kit) 11,12-DHET Immunoassay Kit(1-Kit) 14,15-DHET Human Urine ELISA Kit(1-Kit) 14,15-DHET Hypertension ELISA Kit(1-Kit) 14,15-DHET sEH activity ELISA Kit(1-Kit) 14,15-EET DHET Hypertension ELISA Kit Related articles to: Monkey acylated ghrelin (AG) ELISA kit
- Colorectal cancer (CRC) and non-Hodgkin lymphoma (NHL) are among the most prevalent cancer types globally by incidence and mortality. Both types are influenced differentially by chronic inflammation. Central to this inflammation are inflammatory genes that are meticulously regulated by nuclear factor kappa B (NF-κB) and tumor necrosis factor-α (TNF-α). NF-κB is negatively regulated by IκBα (encoded by ), while TNF-α's actions can be modulated by ghrelin (encoded by ). We investigated four single nucleotide polymorphisms (SNPs) in (rs4648068), (rs2233406), (rs1800629), and (rs1629816) as biomarkers for CRC and NHL risk in a cohort of Kuwaiti individuals. DNA samples from patients and controls were collected and genotyped for all SNPs, and their association with CRC or NHL risk was assessed. While rs4648068 showed a modest association with increased CRC risk, it had no significant impact on NHL risk. Conversely, rs2233406 increased NHL risk without affecting CRC risk. Interestingly, while rs1800629 showed a protective effect against NHL, it showed an increased risk for CRC. Finally, rs1629816 was associated with greater NHL but not CRC risk. Our findings suggests that variations of these inflammatory genes may be useful indicators for predicting cancer risk but might have unpredictable effects on cancer susceptibility, depending on the cancer type. - Source: PubMed
Publication date: 2026/05/23
AlSrayea SaraAlrashid Maryam HBastaki Nasmah KAl-Barrak Jasem - With the ongoing integration of offshore wind power and marine aquaculture, increasing attention has been paid to the potential biological effects of continuous low-frequency noise generated during wind farm operations on surrounding fish species. In this study, juvenile black scrapers (Thamnaconus modestus), a demersal species with low auditory sensitivity, were exposed to 500 Hz noise at low, medium, and high intensities (root-mean-square (RMS) sound pressure levels (SPLrms): 95 ± 5, 115 ± 5, and 135 ± 5 dB re 1 μPa) for 14 days to investigate physiological responses and molecular regulatory mechanisms. Low-intensity noise primarily suppressed the expression of feeding and digestion genes (Ghrl, Prss1) and activated oxidative stress and neuroprotective pathways. Medium-intensity noise caused dysregulation of lipid metabolism genes (Gba1, Degs2), significantly elevated malondialdehyde (MDA) content, and downregulated the expression of key genes in the neutrophil extracellular trap formation pathway (Ncf1, Ncf2, Ncf4). High-intensity noise disrupted the expression of circadian clock genes (Bmal1, Per2) and upregulated cholesterol synthesis pathway genes (Sqle, Cyp51a1, Dhcr24). Collectively, long-term low-frequency noise exposure during operation induced dose-dependent physiological stress on juvenile T. modestus, affecting digestive function, redox balance, lipid metabolism, immune responses, and circadian rhythm regulation. These findings contribute to understanding the potential impacts of low-frequency noise from offshore wind farms on marine fish and suggest that low-frequency noise should be incorporated as a key assessment criterion in the siting of marine ranching and fishery resource conservation. - Source: PubMed
Publication date: 2026/06/09
Song ShiqiShan Xiujuan - Reproductive efficiency in Nellore heifers is fundamental to the profitability and sustainability of beef production in tropical regions, where environmental stress can cause genotype-environment (G×E) interactions that affect fertility. Using 200,258 and 299,885 phenotypic records for heifer early pregnancy (HP) and heifer rebreeding (HR), respectively, we investigated the genetic basis of reproductive plasticity via single-step genomic reaction norms across a continuous environmental gradient (EG) defined from yearling weight records as a proxy for environmental quality. Genomic analyses included 22,556 animals (21,456 females and 1,100 sires) with genotypes imputed to 409,617 single-nucleotide polymorphisms (SNPs). We then performed genome-wide association analyses of the reaction norm intercept (genetic merit) and slope (environmental sensitivity), followed by multi-trait summary analyses and Bayesian fine-mapping of significant loci using imputed whole-genome sequence variants within ±100 kb windows around lead SNPs. - Source: PubMed
Publication date: 2026/06/08
Mota Lucio F MArikawa Leonardo MSantos Daniel J ABrito Luiz FFonseca Larissa F SOliveira Henrique NAlbuquerque Lucia G - Low temperature is an important environmental factor influencing the phenotypic plasticity of the gastrointestinal (GI) tract. However, it remains unclear how GI activity is regulated to cope with low temperature stress. The Daurian ground squirrel (Spermophilus dauricus) is a typical hibernator, which exhibits tolerance to low temperature.This study investigated the expression of hypothalamic appetite-regulating factors and GI activity-regulating factors in ground squirrels exposed to low temperature. The results showed that after continuous low temperature exposure (5 ± 1 °C for 6 days), the immunoreactive expression of c-Fos and neuronal nitric oxide synthase (nNOS) was significantly increased in the arcuate nucleus (ARC), dorsomedial hypothalamic nucleus (DMH), lateral hypothalamic area (LHA), and paraventricular nucleus (PVN); the neuropeptide Y (NPY) expression was upregulated in the ARC, LHA, and PVN. The mRNA expression of gastric nNOS, NPY, CHRM2, HTR4, ADRB2 and GHRL was significantly downregulated under low temperature. Correspondingly, the protein expression of M2mAChR, 5-HT4R, and ADRB2 was decreased, whereas expression of nNOS and GHRL was increased. In the jejunum, the mRNA expression of the above genes, as well as the protein expression of nNOS, M2mAChR, 5-HT4R, ADRB2, and GHRL, was elevated. These results indicate that low temperature stress can significantly activate hypothalamic neural circuits involved in appetite and motility regulation, while suppressing gastric gene expression and activating intestinal gene expression, which likely modulates gastric emptying and enhances intestinal function, enabling the ground squirrel to meet basal energy requirements under short-term low temperature stress, reflecting the remarkable plasticity of the GI tract. - Source: PubMed
Publication date: 2026/05/22
Ju Xiang-YaoMa Yong-PingWang Jian-Li - Obesity is a multifactorial disease characterized by an excessive and abnormal accumulation of body fat that results from both genetic and environmental factors. In this review, we revisited the literature on the variability of obesity-associated genes and their impact on the effectiveness of obesity treatment interventions. Individuals harboring variants of these genes were found to have either better or worse outcomes after weight loss therapies. The majority of the genetic variants were identified in genes that play a role in the leptin-melanocortin pathway (LEPR, NPY, POMC, MC4R, GHRL, GHSR, GLP-1R, BDNF), which regulates food intake and energy expenditure. Both these processes are key elements for energy homeostasis, therefore relevant for the success/failure of weight loss strategies. Some genetic alterations were found to modulate the outcomes of different weight loss interventions, while others were only linked to the effectiveness of bariatric surgery, according to the studies here included and available. Herein, we revisited the most relevant molecular data, with a primarily focus on human studies, concerning how the genetic background influences the outcomes of weight loss interventions. Our aim is to gather relevant information on the genetic data related to weight loss strategies that can be compelling to guide clinical decisions, setting realistic expectations, and ultimately improving the long-term health conditions of individuals with obesity. - Source: PubMed
Publication date: 2026/04/28
Santos-Pereira MarianaGuimarães MartaMonteiro Mariana PPereira Sofia SAzevedo Luísa