Guinea pig CD42 ELISA kit
- Known as:
- Guinea pig CD42 Enzyme-linked immunosorbent assay test reagent
- Catalog number:
- e05c0028
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Blue gene shanghai
- Gene target:
- Guinea pig CD42 ELISA kit
Related genes to: Guinea pig CD42 ELISA kit
- Gene:
- GP1BA NIH gene
- Name:
- glycoprotein Ib platelet subunit alpha
- Previous symbol:
- GP1B
- Synonyms:
- CD42b, GPIbalpha
- Chromosome:
- 17p13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1990-09-10
- Date modifiied:
- 2019-04-23
- Gene:
- GP1BB NIH gene
- Name:
- glycoprotein Ib platelet subunit beta
- Previous symbol:
- -
- Synonyms:
- CD42c, GPIbbeta
- Chromosome:
- 22q11.21
- Locus Type:
- gene with protein product
- Date approved:
- 1991-11-21
- Date modifiied:
- 2019-04-23
- Gene:
- GP5 NIH gene
- Name:
- glycoprotein V platelet
- Previous symbol:
- -
- Synonyms:
- CD42d
- Chromosome:
- 3q29
- Locus Type:
- gene with protein product
- Date approved:
- 1993-11-03
- Date modifiied:
- 2016-01-14
- Gene:
- GP9 NIH gene
- Name:
- glycoprotein IX platelet
- Previous symbol:
- -
- Synonyms:
- CD42a, GPIX
- Chromosome:
- 3q21.3
- Locus Type:
- gene with protein product
- Date approved:
- 1991-03-04
- Date modifiied:
- 2019-04-23
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- Erythropoiesis and megakaryo-/thrombopoiesis occur in the bone marrow proceeding from common, even bipotent, progenitor cells. Recently, we have shown that protective vaccination accelerates extramedullary hepatic erythroblastosis in response to blood-stage malaria of Here, we investigated whether protective vaccination also accelerates extramedullary hepatic megakaryo-/thrombopoiesis. Female Balb/c mice were twice vaccinated with a non-infectious vaccine before infecting with 10 -parasitized erythrocytes. Using gene expression microarrays and quantitative real-time PCR, transcripts of genes known to be expressed in the bone marrow by cells of the megakaryo-/thrombocytic lineage were compared in livers of vaccination-protected and unprotected mice on days 0, 1, 4, 8, and 11 Livers of vaccination-protected mice responded with expression of megakaryo-/thrombocytic genes faster to than those of unvaccinated mice, evidenced at early patency on day 4 , when livers exhibited significantly higher levels of malaria-induced transcripts of the genes and (-values < 0.0001), (-value < 0.001), and , , , , , , , , , and (-values < 0.01). Together with additionally analyzed genes known to be related to megakaryopoiesis, our data suggest that protective vaccination accelerates liver-intrinsic megakaryo-/thrombopoiesis in response to blood-stage malaria that presumably contributes to vaccination-induced survival of otherwise lethal blood-stage malaria. - Source: PubMed
Publication date: 2022/02/14
Wunderlich FrankDelic DenisGerovska DanielaAraúzo-Bravo Marcos J