Mouse SFTPD ELISA
- Known as:
- Mouse SFTPD Enzyme-linked immunosorbent assay test
- Catalog number:
- kt-52529
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Kamiya biomedical company
- Gene target:
- Mouse SFTPD ELISA
Related genes to: Mouse SFTPD ELISA
- Gene:
- SFTPD NIH gene
- Name:
- surfactant protein D
- Previous symbol:
- SFTP4
- Synonyms:
- SP-D, COLEC7
- Chromosome:
- 10q22.3
- Locus Type:
- gene with protein product
- Date approved:
- 1992-06-26
- Date modifiied:
- 2016-10-05
Related products to: Mouse SFTPD ELISA
Related articles to: Mouse SFTPD ELISA
- Lung adenocarcinoma (LUAD) is a leading cause of cancer-related mortality, with hypoxia contributing to tumor progression and treatment resistance. Identifying hypoxia-related biomarkers could enhance prognosis and therapeutic strategies for LUAD. - Source: PubMed
Publication date: 2026/06/03
Alghamdi BandarRocha Sonia - COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presents a broad spectrum of clinical manifestations, ranging from asymptomatic cases to severe, life-threatening respiratory complications. Pulmonary surfactant-associated protein D (SP-D) is a critical component of pulmonary immune defense. The objective of this study was to investigate the association between a specific single-nucleotide polymorphism (SNP) in the SP-D gene, designated as rs721917 (C/T Met31Thr), and its potential impact on susceptibility to and severity of COVID-19. - Source: PubMed
Kolsari Nadia NasirzadehAzaran AzarakhshPirmoradi RoyaMoradi MaryamNashibi RoohangizJalilian Shahram - Due to the global obesity crisis, increasing numbers of women enter pregnancy with overweight or obesity. Their offspring are at greater risk of respiratory complications at birth due to metabolic changes that impact lung development that may reduce capacity for surfactant production. We hypothesize that a high-fat-high-energy diet (HF-HED) negatively impacts late gestation fetal lung development. - Source: PubMed
Publication date: 2026/04/27
Lock Mitchell CHuber Hillary FLi CunOrgeig SandraNathanielsz Peter WMorrison Janna L - The lnc-RNA, miRNA, and mRNA networks have been extensively studied for cancer regulation. Furthermore, ceRNA network analysis has proved as an effective candidate for identifying potential diagnostic biomarkers in a variety of cancers. In this study, we described a novel axis of serum Surfactant protein D ()/miR-335-5p/lnc-HNRNPUL2 proposed by bioinformatics analysis and validated in a pilot human study of CRC versus control & in vitro assay to explore its role in the CRC pathogenesis. - Source: PubMed
Publication date: 2026/03/26
Matboli MarwaElanwar AlyIbrahim WalaaHassan Mohamed KamelAli MarwaKhaled RadwaMontaser ShadyKeshk SaraMedhat HadeelShafei Marwa MMohamed Reham AtefFouad Manar Ahmed - Pulmonary surfactant protein D (SP-D) is an innate immune molecule implicated in lung cancer, where its expression correlates with improved survival and reduced tumor growth. Despite its relevance to lung pathobiology, the transcriptional programs regulated by SP-D and their role in cancer progression and metastasis remain poorly understood. Through integrative analysis of multimodal human data we demonstrate that the SP-D gene (SFTPD) expression is reduced to near absence in metastatic non-small cell lung cancer (NSCLC) tissue, linking its loss to metastatic progression. SFTPD overexpression in A549 lung adenocarcinoma cells significantly decreased tumor growth and metastasis in vivo, and intranasal SP-D protein administration reduced lung tumor burden. Mechanistically, SP-D suppressed several signaling pathways, including IL-4/STAT6 signaling. Analysis of clinical lung tumor samples confirmed that SFTPD expression is associated with reduced IL-4/STAT6 signaling, and patients with low SFTPD expression and elevated IL-4 signaling in their tumors showed the poorest disease-free survival. Our findings demonstrate that SP-D interacts with NSCLC cells to suppress lung cancer progression, in part by blocking of the IL-4/STAT6 signaling pathway. - Source: PubMed
Publication date: 2026/03/08
Mohammadi AliInayatullah MohammedSchlosser AndersPilecki BartoszMarcussen NielsÜnsal SeydaMansoori BehzadBaradaran BehzadTallouzi YousefGjerstorff Morten FrierGraversen JonasRavnskjær KimTiwari Vijay KTerp Mikkel GSorensen Grith Lykke