Rat COMP ELISA
- Known as:
- Rat COMP Enzyme-linked immunosorbent assay test
- Catalog number:
- kt-51102
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Kamiya biomedical company
- Gene target:
- Rat COMP ELISA
Related genes to: Rat COMP ELISA
- Gene:
- COMP NIH gene
- Name:
- cartilage oligomeric matrix protein
- Previous symbol:
- PSACH, EDM1, EPD1
- Synonyms:
- MED, THBS5
- Chromosome:
- 19p13.11
- Locus Type:
- gene with protein product
- Date approved:
- 1994-05-24
- Date modifiied:
- 2016-10-05
Related products to: Rat COMP ELISA
Related articles to: Rat COMP ELISA
- Non-Hispanic Black (BL) adults experience a higher burden of cerebrovascular disease compared with other racial and ethnic groups, for which impaired cerebrovascular function is a well-established risk factor. Previous studies have shown that at rest, cerebrovascular function is lower in young BL adults compared with young WH adults. However, cerebrovascular responses to exercise have never been investigated in BL adults. We hypothesized that young BL males would exhibit attenuated cerebrovascular responses to aerobic exercise compared with their WH counterparts. Cerebrovascular (i.e., middle cerebral artery mean blood velocity; MCAvmean, cerebrovascular conductance index; CVCi and cerebral pulsatility index; PI), cardiovascular (i.e., brachial blood pressure and heart rate), and respiratory (i.e., VO and CO) variables were measured at rest and during incremental and steady-state semi-recumbent cycling exercise in 13 BL and 11 WH males. At rest there were no differences between groups for cerebrovascular, cardiovascular and respiratory measures (all p>0.05). Groups were also comparable for cardiorespiratory fitness (VOpeak, BL:39.5±5.1 vs WH:39.7±6.2 mL/kg/min, p=0.92). During exercise, MCAvmean increased similarly in both groups for both incremental (intensity:p<0.01, race: p=0.44, interaction: p=0.57; e.g., at 50%VOpeak, BL: ∆16.2±4.3 vs WH: ∆15.7±8.7 cm/s) and steady-state (intensity:p<0.01, race: p=0.45, interaction: p=0.98; e.g., at 50 watts, BL: ∆5.8±2.3 vs WH: ∆4.8±5.0 cm/s) exercise. There was also no main effect of race for CO, CVCi or PI during either exercise protocol (all p>0.05). Thus, contrary to our hypothesis, no detectable racial differences in cerebrovascular responses to incremental or steady-state aerobic exercise were found in this cohort of young, otherwise healthy males. - Source: PubMed
Publication date: 2026/09/22
Taherzadeh ZibaAlhalimi Taha AOldham Zachary RKissell Claire EYoung Benjamin EFadel Paul J - The periparturient period in mammals is characterized by reduced insulin action, which allows nutrient partitioning to support fetal growth and milk synthesis. The sphingolipid ceramide is an established interrogator of insulin signaling in non-ruminants and accumulates during this period in dairy cows. We investigated the effects of short-term nutrient restriction (NR) on glucose tolerance and ceramide metabolism in multiparous ewes (n = 19) during this period. Ewes were fed ad libitum or subjected to two 5-d 50% NR periods in late gestation and early lactation. NR reduced circulating glucose and insulin and increased fatty acids, consistent with negative energy balance. Milk yield was lowered by lactational NR; however, production efficiency improved. Serial intravenous glucose tolerance tests revealed impaired glucose tolerance following gestational NR that was sustained across lactation, evidenced by greater glucose and fatty acid area-under-the-curves regardless of insulin secretion. Most plasma and milk ceramide subclasses were highly abundant in C24:0 and C24:1 acyl moieties; however, plasma lactosylceramide was differentially enriched with C16:0 and C20:1. NR induced biphasic shifts in plasma ceramide species and subclasses across the periparturient period, with peak ceramide and hexosylceramide species concentrations in early lactation prior to the second NR and opposite patterns in lactosylceramides. Milk ceramide and hexosylceramide profiles were distinct from plasma; however, lactosylceramide species responded similarly. Plasma lactosylceramide species also had a strong negative correlation to milk yield. Overall, NR induced coordinated endocrine, metabolic, and sphingolipid adaptations in periparturient ewes, implicating ceramides as potential mediators of metabolic regulation during this critical physiological transition. - Source: PubMed
Publication date: 2026/09/22
Farricker Miranda JJudge Josie LSmith AndrewHill Shalise TDeme PragneyHaughey Norman JMcFadden Joseph WDavis Amanda N - Humour and laughter have received increasing attention in narrative criminology, but existing scholarship has tended to collapse them into a single analytic entity. In this paper, we foreground the awkward spaces that lie in the space between. Based on two research projects carried out with street and justice-involved men in Scotland, where the fusion of masculinities, humour and 'patter' has for many years formed an important aspect of culture and identity, we first examine the dynamics of inclusion and exclusion in moments where laughter follows humour. We then move onto an examination of humour without laughter and laughter without humour, developing a juxtaposition between humour as and laughter as , analysing both as strategies to maintain face and manage shame. In so doing we contribute to the probing of the often unseen or intangible aspects of narratives in criminological contexts that nonetheless can be deeply revealing. - Source: PubMed
Publication date: 2026/09/22
Schinkel MargueriteFraser Alistair - The adipokinetic hormone/corazonin-like peptide (ACP) functions as a hormone in many arthropod species. The ACP-encoding transcript is expressed in the neural tissues and sperm duct of the ornate spiny lobster, Panulirus ornatus, a species of importance to the aquaculture industry. In this study, the presence of the ACP precursor peptide was verified in the medial sperm duct and spermatophore of P. ornatus through peptide fragments identified by proteomic analysis. We examined the proteome of three tissues: the medial sperm duct, its spermatophoric contents, and a deposited 'tarspot', identifying other proteins involved with multiple functions including immune response, amelioration of oxidative stress, antimicrobial action, energy usage, and muscle function. To understand a potential role for ACP precursor peptides in these tissues, a screen targeting nine bacterial strains was carried out however no antimicrobial activity was found for ACP or related peptides. A 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay was used to identify potential mild antioxidant activity in a peptide from the ACP precursor providing a putative function in the sperm duct. The histology of the medial sperm duct of P. ornatus, together with the protein constituents of the medial sperm duct, its contents, and tarspot are presented to provide a greater understanding of the male reproductive system of the ornate spiny lobster. - Source: PubMed
Publication date: 2026/09/22
Glendinning SusanWang TianfangOlsson MalinTran Trong DMcMillan DavidFitzgibbon Quinn PSmith Gregory GVentura Tomer - In recent years, the population of Chinese horseshoe crabs (Tachypleus tridentatus) has declined sharply. As a living fossil of the ocean, they have an extremely slow growth cycle. To protect this endangered species, research has focused on identifying the optimal conditions required for its growth and development. Previous studies have focused on analyzing the optimal feed for T. tridentatus at various life stages. However, the optimal conditions required for the growth and development of first instar juveniles remain unclear. Furthermore, there is a lack of accurate and effective knowledge regarding the cultivation of first instar juveniles in aquaculture. Therefore, this study investigates the effects of feed and substrate on juvenile growth and development. Four experimental groups were established: a no-substrate, no-feeding group (WK group), a no-substrate, oyster feeding group (WS group), a group with sandy-mud substrate but no feeding (SNK group), and a group with sandy-mud substrate and oyster feeding (SNS group). The results were analyzed based on experimental records, proteomics, and microbiomics data. The results indicated that the SNS group exhibited the highest molting rate, as well as the highest weights for both first- and second instar juvenile horseshoe crabs. This indicates that the combined effect of oysters and the substrate is far greater in molting rates than the effect of either alone. Based on the proteomic results, under sandy-mud substrate conditions, oyster feeding induced substantial accumulation of mannosyl-oligosaccharide 1,2-alpha-mannosidase IA-like and Spartin, while reducing creatinase accumulation. With oyster feeding, the addition of sandy-mud substrate led to substantial accumulation of juvenile hormone acid O-methyltransferase-like isoform X1 and thromboxane-A synthase-like. Consistent with the microbiome results, juvenile horseshoe crabs in the SNS group exhibited higher average relative abundances of intestinal bacteria including Vibrionaceae, Thalassobius, and Defluviimonas. - Source: PubMed
Publication date: 2026/09/17
Li DuyuXie MujiaoChen XiaohaiLi TingWang AijvJiang SuhuiXie Xiaoyong