IL-5, human recombinant
- Known as:
- Interleukin-5, H. sapiens Rec.
- Catalog number:
- bc-278
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Kamiya biomedical company
- Gene target:
- IL-5 human recombinant
Related genes to: IL-5, human recombinant
- Gene:
- CSF2RB NIH gene
- Name:
- colony stimulating factor 2 receptor beta common subunit
- Previous symbol:
- IL3RB
- Synonyms:
- IL5RB, CD131, betaGMR
- Chromosome:
- 22q12.3
- Locus Type:
- gene with protein product
- Date approved:
- 1991-08-07
- Date modifiied:
- 2017-07-12
- Gene:
- IL5 NIH gene
- Name:
- interleukin 5
- Previous symbol:
- -
- Synonyms:
- IL-5, EDF, TRF
- Chromosome:
- 5q31.1
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-22
- Date modifiied:
- 2015-07-06
- Gene:
- IL5RA NIH gene
- Name:
- interleukin 5 receptor subunit alpha
- Previous symbol:
- IL5R
- Synonyms:
- CDw125, CD125
- Chromosome:
- 3p26.2
- Locus Type:
- gene with protein product
- Date approved:
- 1992-06-18
- Date modifiied:
- 2016-10-11
- Gene:
- LRR1 NIH gene
- Name:
- leucine rich repeat protein 1
- Previous symbol:
- PPIL5
- Synonyms:
- MGC20689, LRR-1
- Chromosome:
- 14q21.3
- Locus Type:
- gene with protein product
- Date approved:
- 2002-11-20
- Date modifiied:
- 2014-11-18
Related products to: IL-5, human recombinant
Related articles to: IL-5, human recombinant
- Asthma is a Th2-skewed inflammatory disorder characterized by eosinophilic infiltration, cytokine dysregulation, and airway remodeling. Emerging evidence highlights the role of immunometabolic pathways and the gut-lung axis in asthma pathogenesis. - Source: PubMed
Publication date: 2026/06/03
Yang HangruiWu GeyuanLiang ShuoZan RaonaChen YitaoYuan WeiweiChen HongHuang Guiqiong - Shift work sleep disorder (SWSD) is prevalent among female nurses and is associated with significant health morbidities. While inflammation is implicated in SWSD, how it relates to brain network alterations and clinical symptoms remains underexplored. This study aimed to investigate the associations among peripheral inflammation, brain functional network topological disruptions, clinical symptoms, and transcriptomic signatures in female nurses with SWSD. - Source: PubMed
Publication date: 2026/06/02
Gu Si-YuWang Shu-FangWang ShuYang Hu-ChengLiu Jian-PingJi Ya-NanZhang HuiChen Hai-JuanChen LiSong Chun-MeiLi Qing-HeDai Zhen-YuPan Ping-Lei - Asthma is a prevalent chronic airway disease with unmet therapeutic needs. Aster tataricus L. f. (AT), a traditional herbal medicine used for respiratory conditions, shows potential for asthma treatment; however, its underlying pharmacological mechanisms remain largely unexplored. This study aimed to systematically investigate the potential therapeutic effects of AT against asthma and elucidate its underlying molecular mechanisms by integrating network pharmacology prediction, molecular docking validation, and in vivo experimental confirmation. - Source: PubMed
Publication date: 2026/06/15
Zang YunZhang Jia-NingYang Si-QiWang YanLi Hui-FengTan Jin-YanYou Rong-LiZhang YiWang Ying-LiCheng Yan-Gang - Nowadays, the management of chronic obstructive airway diseases is shifting from traditional diagnostic labels toward a precision medicine approach based on "treatable traits." Among these, blood eosinophilia is emerging as a biomarker of type 2 (T2) inflammation across asthma and chronic obstructive airway diseases (COPD), even if its role as diagnostic tool and therapeutic target remains debated. In this manuscript we presented a clinical case of a 60-year-old male, former mild smoker (5 p/y), initially diagnosed with severe COPD with persistent airflow limitation, frequent severe exacerbations and persistent eosinophilia, but a history of asthma and nasal polyposis. After six months with optimization of inhaled therapy and clinical reassessment, the diagnosis of "severe COPD" shifted to the diagnosis of "severe eosinophilic asthma". Considering the new diagnosis, he was prescribed mepolizumab on top of triple inhaled therapy. After 1 year, the clinical response was excellent in terms of symptoms control, exacerbations reduction and OCS sparing, despite no improvement in lung function. Starting from this clinical case, the aim of this mini review is to describe the role of eosinophilic inflammation in asthma and COPD. While eosinophilic inflammation is a common feature of asthma, COPD is usually characterized by neutrophilic inflammation, even if, a subset of patients with COPD has eosinophilic inflammation. In this context, blood eosinophilia might represent a clinically actionable trait to guide diagnosis and personalized therapy in chronic airway diseases even if it should not be targeted in isolation but be integrated into a multidimensional assessment. - Source: PubMed
Publication date: 2026/06/01
Massetti GiulioMartella ManuelRuini CristinaRuggieri ValentinaBeghe Bianca - Allergic reactions have surged to unprecedented levels, impacting about 30% of people globally. Fungi are a significant source of allergens, responsible for approximately 6% of respiratory diseases in the general population. However, identifying the exact cause of respiratory allergies is not always possible. - Source: PubMed
Publication date: 2026/06/15
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