Polyclonal TIRP (C2)
- Known as:
- Polyclonal TIRP (C2)
- Catalog number:
- pc-445
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Kamiya biomedical company
- Gene target:
- Polyclonal TIRP (C2)
Related genes to: Polyclonal TIRP (C2)
- Gene:
- AAR2 NIH gene
- Name:
- AAR2 splicing factor
- Previous symbol:
- C20orf4
- Synonyms:
- bA234K24.2
- Chromosome:
- 20q11.23
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-21
- Date modifiied:
- 2019-02-18
- Gene:
- AARSD1 NIH gene
- Name:
- alanyl-tRNA synthetase domain containing 1
- Previous symbol:
- -
- Synonyms:
- MGC2744
- Chromosome:
- 17q21.31
- Locus Type:
- gene with protein product
- Date approved:
- 2005-11-15
- Date modifiied:
- 2018-05-03
- Gene:
- ABCA2 NIH gene
- Name:
- ATP binding cassette subfamily A member 2
- Previous symbol:
- ABC2
- Synonyms:
- -
- Chromosome:
- 9q34.3
- Locus Type:
- gene with protein product
- Date approved:
- 1994-03-16
- Date modifiied:
- 2016-10-05
- Gene:
- ABCB1 NIH gene
- Name:
- ATP binding cassette subfamily B member 1
- Previous symbol:
- PGY1, MDR1, CLCS
- Synonyms:
- P-gp, CD243, GP170, ABC20
- Chromosome:
- 7q21.12
- Locus Type:
- gene with protein product
- Date approved:
- 1986-01-01
- Date modifiied:
- 2015-11-13
- Gene:
- ABCB10 NIH gene
- Name:
- ATP binding cassette subfamily B member 10
- Previous symbol:
- -
- Synonyms:
- EST20237, M-ABC2, MTABC2
- Chromosome:
- 1q42.13
- Locus Type:
- gene with protein product
- Date approved:
- 1999-10-26
- Date modifiied:
- 2016-10-05
Related products to: Polyclonal TIRP (C2)
Related articles to: Polyclonal TIRP (C2)
- A history of coronary heart disease (CHD) increases the risk of Brain-Heart Syndrome (BHS) after acute stroke, partly through heightened inflammatory responses. Evolocumab, a PCSK9 inhibitor, has anti-inflammatory properties, but its transcriptomic effects in BHS patients with CHD remain unclear. This study aims to identify evolocumab-associated transcriptomic changes and inflammation-related biomarkers in this population. - Source: PubMed
Publication date: 2026/05/22
Dong HuijieGong XingZhao ZhenrongJoyama YukiJi XiaofeiQu Peng - Cochlin, encoded by the COCH gene, mediates innate immunity against bacterial infections by segregating pathogens and recruiting immune cells through its N-terminal LCCL domain. This domain is cleaved and secreted to attract macrophages and neutrophils, but its core motif has remained unclear. - Source: PubMed
Publication date: 2026/03/10
Kim HyoyeolBae Seong HoonJang Seung HyunYoon SoljeeKim KyeonghwanJang Seung HyeonGee Heon YungKim YoungSooJung Jinsei - Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease, triggered by a complex interplay between genetic, environmental and epigenetic factors. We investigated the methylation profile of peripheral CD4(+) lymphocytes from PBC patients compared to healthy controls (HC) and autoimmune hepatitis (AIH) patients, to elucidate gene specific epigenetic modifications that contribute to PBC pathogenesis, as similar data are limited. - Source: PubMed
Publication date: 2025/09/09
Arvaniti PinelopiZachou KalliopiLyberopoulou AggelikiSevdali EiriniGabeta StellaSpeletas MatthaiosRenaudineau YvesDalekos George N - Limited data exist on the immunoregulatory mechanisms involv ed in thyroid cancer, particularly in aggressive forms. This study aimed at identifying the expression profiles of immune-related genes and miRNAs in anaplastic (ATC) and poorly differentiated thyroid carcinomas (PDTC) associated with papillary carcinoma (PTC) components. Immune-related genes were investigated using the nCounter® PanCancer Immune Profiling Panel in separate ATC and PTC components of 12 cases, and in PDTC component only of nine additional cases associated with PTC. Global miRNAs profiling was also analyzed separately in ATC and PTC components of 8 out of the 12 cases. Comparative analysis between ATC and matched PTC components revealed largely stable gene expression patterns, with only a few genes deregulated. Of these, five genes (MAP3K1, PRKCD, CYFIP2, BLNK, and EPCAM) were downregulated, while six (RIPK2, ITGB1, CCL3L1, ITGA5, PLAUR, and TICAM2) were upregulated in ATC. Furthermore, 54 miRNAs were significantly upregulated in ATC, as compared to PTC components. One of the most regulated pathways was the MAPK signaling, with six of these deregulated miRNAs targeting the MAP3K1 gene. Comparing ATC and PDTC, over 200 genes were differentially expressed between PDTC and ATC samples, involving all major immune-related pathways, with a consistent downregulation in PDTC. In conclusion, ATC displays high levels of expression of immunoregulatory genes as compared to PDTC. Moreover, a subset of genes and miRNAs is significantly de-regulated along progression from PTC to ATC, suggesting their potential role as biomarkers and involvement in key functional mechanisms. - Source: PubMed
Publication date: 2025/09/18
Orlando GiuliaNapoli FrancescaZambelli VanessaMaletta FrancescaCapella GiuliaDuregon EleonoraVolante MarcoPapotti Mauro - Enterovirus 71 (EV-A71) is a major pathogen of severe hand, foot and mouth disease (HFMD) in children, but the mechanism by which it develops into severe HFMD remains unclear, especially the role of macrophage-mediated immune dysregulation. - Source: PubMed
Publication date: 2025/08/21
Wang MuqiZhang MengDeng HuilingZhang YufengLiu ChenruiChen YuanZhang ChutingZhang WenJia XiaoliDang ShuangsuoLi Yaping