Human Polyclonal KIR2DS4 Ab
- Known as:
- Human Polyclonal KIR2DS4 Antibody
- Catalog number:
- a1779
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- ABclonal
- Gene target:
- Human Polyclonal KIR2DS4
Related genes to: Human Polyclonal KIR2DS4 Ab
- Gene:
- KIR2DS4 NIH gene
- Name:
- killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
- Previous symbol:
- -
- Synonyms:
- cl-39, KKA3, nkat8, CD158i
- Chromosome:
- 19q13.42
- Locus Type:
- gene with protein product
- Date approved:
- 1997-11-14
- Date modifiied:
- 2016-01-20
Related products to: Human Polyclonal KIR2DS4 Ab
Related articles to: Human Polyclonal KIR2DS4 Ab
- The killer-cell immunoglobulin-like receptors (KIR) are a family of activating and inhibitory Class I human leukocyte antigen (HLA-I) binding receptors expressed on natural killer (NK) cells and subsets of T cells. The KIR detect HLA-I molecules in a peptide-dependent manner, with some KIR displaying exquisite peptide specificity. Studying peptide recognition by KIR often uses TAP-deficient cell lines expressing single HLA-I alleles, which are heterogenous and time consuming to generate. Here, we established an alternative approach using peptide-exchange technologies hitherto developed for studying T cell recognition of HLA-I. - Source: PubMed
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