BDNF & NTF4 Protein Protein Interaction Antibody Pair
- Known as:
- BDNF & NTF4 Protein Protein Interaction Antibody Pair
- Catalog number:
- DI0499
- Product Quantity:
- 1 Set
- Category:
- -
- Supplier:
- Abno
- Gene target:
- BDNF & NTF4 Protein Interaction Antibody Pair
Related genes to: BDNF & NTF4 Protein Protein Interaction Antibody Pair
- Gene:
- BDNF NIH gene
- Name:
- brain derived neurotrophic factor
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 11p14.1
- Locus Type:
- gene with protein product
- Date approved:
- 1991-01-15
- Date modifiied:
- 2016-06-01
- Gene:
- BDNF-AS NIH gene
- Name:
- BDNF antisense RNA
- Previous symbol:
- BDNFOS
- Synonyms:
- BT2A, BT2B, BT2C, BT2D, NCRNA00049, BDNF-AS1, BDNFAS
- Chromosome:
- 11p14.1
- Locus Type:
- RNA, long non-coding
- Date approved:
- 2005-02-01
- Date modifiied:
- 2017-08-09
- Gene:
- NTF4 NIH gene
- Name:
- neurotrophin 4
- Previous symbol:
- NTF5
- Synonyms:
- NT-4/5, GLC1O
- Chromosome:
- 19q13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1992-10-15
- Date modifiied:
- 2014-11-19
Related products to: BDNF & NTF4 Protein Protein Interaction Antibody Pair
Related articles to: BDNF & NTF4 Protein Protein Interaction Antibody Pair
- The tropomyosin-related kinase (Trk) B neurotrophin receptor is essential for ovarian germ cell survival and primordial follicle formation, but the contributions of its ligands, brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4), are unknown. We have investigated their expression and regulation in developing human and mouse ovaries. BDNF expression increased with increasing gestation, expression of human NTF4 and of both Ntf5 and Bdnf in the mouse was unchanged. Bdnf expression was dramatically lower than Ntf5 in the mouse, but levels were comparable in the human. Human fetal ovarian somatic cells expressed BDNF. Activin A selectively regulated BDNF and Ntf5 expression in human and mouse, respectively, identifying an oocyte/somatic signaling pathway which might mediate the pro-survival effects of activin. These data reveal that expression and regulation of the TrkB ligands are differentially controlled in the developing ovaries of humans and mice, and identify BDNF as a potential regulator of germ cell fate in the human fetal ovary. - Source: PubMed
Childs Andrew JBayne Rosemary A LMurray Alison AMartins Da Silva Sarah JCollins Craig SSpears NorahAnderson Richard A