MMP9 Antibody
- Known as:
- MMP9 Antibody
- Catalog number:
- 29091
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Signalway
- Gene target:
- MMP9 Antibody
Related genes to: MMP9 Antibody
- Gene:
- MMP9 NIH gene
- Name:
- matrix metallopeptidase 9
- Previous symbol:
- CLG4B
- Synonyms:
- -
- Chromosome:
- 20q13.12
- Locus Type:
- gene with protein product
- Date approved:
- 1990-03-14
- Date modifiied:
- 2015-02-23
Related products to: MMP9 Antibody
Related articles to: MMP9 Antibody
- Maternal infection (MI) can result in significant neurodevelopmental abnormalities and long-term neurological sequelae in offspring. This study was designed to investigate MI-induced alterations in synaptic protein expression, axonal morphology, dendritic, and spine morphology, and behaviour in a neonatal rat model of bacterial meningitis. - Source: PubMed
Publication date: 2026/05/11
Thejaswini JayakumarNegetha Veerakalyana KumarRajan Koilmani Emmanuvel - Matrix metalloproteinase-9 (MMP-9) detection is crucial for the early screening and treatment monitoring of infantile hemangioma. Herein, a nanoconfinement catalysis-enhanced electrochemiluminescence (ECL) aptasensor was fabricated for the sensitive detection of MMP-9. CoO nanoparticles were electrochemically deposited onto an ordered silica nanochannel film (SNF), which not only exhibited electrocatalytic oxidation activity toward luminol and HO but also possessed peroxidase (POD)-like activity. The synergistic effect between CoO and the confinement effect of SNF remarkably amplified ECL from the luminol-HO system. After functionalizing the electrode surface with epoxy groups, MMP-9 aptamers were covalently immobilized to construct the aptasensor. ECL signal quenching, attributable to the spatial hindrance and elevated interfacial resistance following the specific MMP-9/aptamer binding, served as the basis for the quantitative detection of MMP-9. The sensor displayed a wide linear response range (0.001 to 100 ng mL), a low detection limit of 0.1 pg mL, and high selectivity, reproducibility, and stability. - Source: PubMed
Publication date: 2026/05/07
Yan TaoranMa XinyingXi Fengna - Acute ultraviolet exposure disrupts the epidermal barrier, induces oxidative stress, and accelerates extracellular matrix degradation, necessitating effective strategies for photodamage repair. Here, we establish a molecular-weight-graded agarose system-Aga-U, Aga-H, Aga-M, and Aga-L-to assess the effect of molecular weight on the physicochemical and biological properties of agarose. Controlled hydrolysis generated agarose fractions with progressively reduced molecular weight, resulting in enhanced solubility, hydrophilicity, fluidity, and antioxidant capacity. All fractions exhibited good cytocompatibility and promoted zebrafish caudal-fin regeneration, with Aga-L demonstrating the strongest bioactivity. and evaluations, including fibroblast assays and zebrafish and UV-induced acute photodamage mouse models, revealed that Aga-L most effectively restored the epidermal barrier, reduced oxidative stress, and enhanced collagen deposition. Molecular analyses showed that Aga-L downregulated MMP-1, MMP-2, MMP-9, p-c-Fos, and p-c-Jun and upregulated Nrf2, HO-1, Col I and Col III. These findings identify low-molecular-weight agarose as a potent bioactive polysaccharide for repairing UV-induced skin injury and provide a basis for developing agarose-based therapeutic strategies. - Source: PubMed
Publication date: 2026/05/07
Guo YingXie YiLi YongjunTian BeiXiao Jianxi - Periodontitis is a chronic inflammatory disorder characterized by tissue degradation and bone loss. Lipopolysaccharide (LPS) accelerates disease progression by host immune activation, inducing localized inflammatory infiltration and osteoclastogenesis, and disrupting bone metabolic homeostasis. Adipose-derived mesenchymal stem cells (ADSCs) exert anti-inflammatory, anti-apoptotic, and regenerative effects via paracrine signaling. - Source: PubMed
Publication date: 2026/05/10
Luo ShiyiMa ShuAo ManWang YueyueLi WeiSun JianglingGu XuanyanLiu ZefeiChen ZhuLi Long - Bone cancer is an uncommon type of malignant tumor that begins in bone tissue and can destroy normal bone structure or develop as metastases from another malignancy. At 30% of all bone cancer cases, osteosarcoma is the most typical primary malignant bone cancer. It frequently appears in the metaphyses of adolescent long bones, which have the most capacity for growth. Therefore, the recent study aims to synthesize safer phytoconstituent mediated- palladium nanoparticles (PdNPs) utilizing aqueous leaves extract of Psidium guajava (PGLE) and for insight into the produced nanoparticles' therapeutic impacts on the pathways that inhibit MG-63 cancer cell lines. The obtained PdNPs displayed amorphous spherical morphology with an average diameter of 4.72±1.616 nm and a zeta potential value of -14.8 mV. The extract-suspended palladium nanoparticles (PdNPs-PGLE) exhibited a lower IC value of (89.81 ± 0.32 µg/ml) and had a superior cytotoxic effect towards MG-63 cell growth compared to the PGLE (110.65 ± 1.07µg/ml) and PdNPs (198.22 ± 0.24µg/ml) samples. It was shown that (PdNPs-PGLE) increased significantly the % of total apoptotic cells compared to PGLE and PdNPs with higher intensity comet nucleus in treated cells compared to control cells. It is shown that there was an arrest in the S cell cycle phase in MG-63-treated cells. The PdNPs-PGLE had a significant decrease in wound closure % (45.21) compared to control untreated cells (58.78). Furthermore, the PdNPs-PGLE severely suppresses the capacity of MG-63 of colony formation, with a plating efficiency of 0.9% and a surviving fraction of 0.009, compared to control cells. Additionally, the estimation of the expression of protein levels using the ELISA technique revealed that there was an increase in the Bax, cleaved active Caspase-3, and TP53 expression levels with a decrease in the Bcl-2, CDK2, MMP-2, and MMP-9 expression in the PdNPs-PGLE-treated cells compared to control cells (p < 0.05) .These findings point out the potential of Psidium guajava-mediated green synthesis not only as an eco-friendly route for nanoparticle fabrication but also as a means to harness phytochemical-nanomaterial synergy. - Source: PubMed
Publication date: 2026/05/10
Hanna Demiana HTaher Basma MEl-Desouky Mohamed A