c-Jun (Phospho-Ser63) Antibody
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- - Source: PubMed
Publication date: 2026/09/25
Koutsoftas Anthony DStrong Katie A - Cohabitation represents a significant shift in family structures as they undergo demographic and economic transitions. This practice is a common phenomenon among Nigerian university undergraduates. Therefore, this study examined the demographic factors that determine cohabitation practices among undergraduates in Osun State, Nigeria. Guided by the individualization theory, the research design adopted was a survey, and questionnaire and in-depth interview instruments were used to collect the data. A sample of 400 respondents was included in the quantitative analysis, while 18 participants were included in the qualitative aspects of the analysis. Descriptive (frequency and percentages) and bivariate (chi-square test and correlation) were used to analyze the quantitative data, while the qualitative data were content analyzed. The findings revealed that a majority of the respondents have high (45.3%) knowledge of cohabitation practice, and pre-marital cohabitation (56.5%) is one of the major dimensions of cohabitation reported by the respondents. Determining factors adduced for engaging in cohabitation were the urge to be a 'baby mama' (77.5%) and economic benefits (74.5%); while 73.0% of them have a regular pattern of practicing cohabitation. About 42.0% of them have good perception, and less than 55% have a negative attitude towards cohabitation. A significant age difference in knowledge of cohabitation (χ2 = 96.96, ρ<0.01) and knowledge of cohabitation was positively correlated with attitude (r = 0.611, p<0.01) and perception (r = 0.528, p<0.01) among the respondents. Similarly, perception of cohabitation was positively correlated with attitude towards cohabitation (r = 0.187, p < 0.01). The implication of this finding is that high knowledge will lead to high perception and positive attitude towards disengaging from cohabitation practices. Adolescents and youths should be enlightened about the negative consequences of cohabitation relationships that may jeopardize their future endeavours. - Source: PubMed
Publication date: 2025/06/30
Akokuwebe Monica Ewomazino - Acute and subacute effects of crude oil's water-soluble fraction (WSF) and associated histopathological changes in the gills and liver of juvenile Coptodon guineensis were investigated. An acute toxicity test (96 hrs) was performed by a static non-renewal method at various concentrations of 0.25, 1, 5, 15, and 30%. Similarly, test organisms were tested in 2.5% sublethal concentration for 28 days. Water quality parameters, heavy metals, and total polycyclic aromatic hydrocarbons (PAHs) were determined using standard methods. After fish exposure in WSF of crude oil, gills and liver were harvested, stained with hematoxylin/eosin, and later prepared for photomicrography. Results revealed the LC50 as 26.73% (26.73 g/L), while total PAHs and heavy metal (Ni, Cd, and Pb) levels varied significantly (p < 0.05) in Coptodon guineensis over the period of exposure. Histopathological alterations were evident in gills and further revealed the presence of deformed secondary lamellae, with corresponding congestion of the passive central vein and cytoplasmic vacuolation in the liver. Apart from toxicity values to unravel the adverse impacts of the bioavailable water-soluble fraction of crude oil on juvenile Coptodon guineensis, the histopathological assay revealed underlying sub-lethal responses that can serve as early warning signals. Keywords: Bioassay, water-soluble fraction, crude oil, histopathological, Coptodon guineensis. - Source: PubMed
Publication date: 2025/06/30
Bello BeatriceLawal OlayideOlumayede GbengaAgbo Stanley - Monkeys are phylogenetically close to humans and are therefore used in a lot of research models. This study aimed to determine the basic physiological and haematological parameters in four different species of captive monkeys during the rainy season. Fourteen adult monkeys at the University of Ibadan Zoological Garden were used for this study (3 - Cercocebus sebaeus, 3 - Cercopithecus mona, 3- Erythrocebus patas and 5- Papio Anubis). Dry-bulb temperature and relative humidity were recorded concurrently with the measurement of rectal temperature (RT), body surface temperatures (BST), respiratory (RR) and heart rates (HR). Blood sample were collected for the evaluation of haematological parameters. The dry-bulb temperature and relative humidity were 25.9℃ and 75%, respectively. The Erythrocebus patas monkey had mean RT value of 38.23 ± 0.2℃, while the Cercocebus sebaeus monkey had 38.87 ± 0.7℃ when compared to that of Papio anubis and Cercopithecus mona monkey (38.4 ± 0.3℃ and 38.53 ± 0.6℃, respectively). The mean RR value of 40.0 ± 2.3 cycle/min in Erythrocebus patas monkey was significantly (p ˂ 0.05) higher than 27.33 ± 1.3 cycles/min and 21.60 ± 1.9 cycles/min in Papio anubis and Cercocebus sebaeus monkey, respectively. The mean bias difference of rectal temperature versus eye temperature (0.8643 ± 0.749) was significantly (p ˂ 0.05) lower than the mean bias differences of the rectal temperature versus forehead (2.19 ± 0.75), but was not statistically (p ˃ 0.05) different from the value of 1.471 ± 0.9 obtained in the comparison of rectal temperature versus base of the tail temperature. The haematological parameters were not significantly different among the species. In conclusion, the basic thermoregulatory apparatus and haematological parameters of the different species of monkeys were not significantly different and the values recorded were within the established range for the monkey. - Source: PubMed
Publication date: 2025/06/30
Ake AyodeleOgunro BamideleAjaebili AugustineArowolo IsaacKpasham LuimommeiObasa AdedunsolaLadagu AmanyOlopade J O - Globally, human metapneumovirus (hMPV) constitutes a more significant proportion of acute respiratory tract infections (ARTIs), which are a primary cause of morbidity and mortality in children. A range of viruses, such as influenza viruses, respiratory syncytial virus (RSV), picornaviruses, coronaviruses, parainfluenza viruses, and adenoviruses, have been linked to various respiratory syndromes across all age categories. Notably, some of these viruses circulate and co-infect individuals, increasing the possibility of resulting in complex interactions that may affect disease severity, immune response, and epidemiology. It is also known that the majority of children contract hMPV by the age of 5, with the most severe cases found in infants, comprising both symptomatic and asymptomatic infections. Although hMPV is widely common, there are currently no approved vaccines or specific antiviral therapies available, highlighting the need for more research into focused treatments and vaccine development. Improvements in molecular diagnostics have increased detection rates, though difficulties persist in disease monitoring and management. The 2024-2025 current outbreak in China commenced in December 2024 and has experienced a rapid rise in cases, especially among children aged 14 and younger. Additionally, other countries like the United Kingdom (UK), France, and Germany have reported cases of the virus, reflecting its extensive spread. Consequently, an understanding of the epidemiology of hMPV is essential for creating effective targeted interventions. This review provides a global perspective of hMPV and points out knowledge gaps to drive future research initiatives in its management, prevention, and control. - Source: PubMed
Publication date: 2025/06/30
Ayanwale S OAudu R AOmilabu S ACadmus Simeon I B