GST- SURVIVIN T34A Expression Vector
- Known as:
- GST- SURVIVIN T34A Expression Vector
- Catalog number:
- 132006
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Ch3biosystems
- Gene target:
- GST- SURVIVIN T34A Expression Vector
Related genes to: GST- SURVIVIN T34A Expression Vector
- Gene:
- GSPT1 NIH gene
- Name:
- G1 to S phase transition 1
- Previous symbol:
- -
- Synonyms:
- GST1, ETF3A, eRF3a
- Chromosome:
- 16p13.13
- Locus Type:
- gene with protein product
- Date approved:
- 1992-02-07
- Date modifiied:
- 2018-01-22
- Gene:
- GSTA2 NIH gene
- Name:
- glutathione S-transferase alpha 2
- Previous symbol:
- GST2
- Synonyms:
- -
- Chromosome:
- 6p12.2
- Locus Type:
- gene with protein product
- Date approved:
- 1986-01-01
- Date modifiied:
- 2015-09-10
- Gene:
- GSTA6P NIH gene
- Name:
- glutathione S-transferase alpha 6, pseudogene
- Previous symbol:
- GSTAP1
- Synonyms:
- -
- Chromosome:
- 6p12.2
- Locus Type:
- pseudogene
- Date approved:
- 1993-05-26
- Date modifiied:
- 2014-11-19
- Gene:
- GSTA7P NIH gene
- Name:
- glutathione S-transferase alpha 7, pseudogene
- Previous symbol:
- GSTAP2
- Synonyms:
- GSTAP6
- Chromosome:
- 6p12.2
- Locus Type:
- pseudogene
- Date approved:
- 1994-05-19
- Date modifiied:
- 2014-11-18
- Gene:
- GSTA8P NIH gene
- Name:
- glutathione S-transferase alpha 8, pseudogene
- Previous symbol:
- -
- Synonyms:
- GSTAP7
- Chromosome:
- 6p12.2
- Locus Type:
- pseudogene
- Date approved:
- 2014-06-04
- Date modifiied:
- 2014-06-04
Related products to: GST- SURVIVIN T34A Expression Vector
Related articles to: GST- SURVIVIN T34A Expression Vector
- To investigate the gene expression of MAPEG in the cortex of concanavalin A (Con A)-induced mouse immune inflammatory model and the effect of cyclosporine A (Cs A). - Source: PubMed
Zhang Xiang-NanQi Lou-YangZhu Dan-YanLou Yi-Jia - The expressions of membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG), a superfamily involved in both inflammation and cell protection, were investigated in an in vitro system of mouse embryonic stem (ES) cell-derived hepatic tissue. Gene expressions of all MAPEG members were demonstrated in a developmental-dependent manner in the derived hepatic tissue. The protein expression of microsomal glutathione S-transferase 1 (MGST1) was not detected until differentiating day 14. It gradually increased by maturation of hepatic tissue. The microsomes of ES cell-derived hepatic tissue possessed the MGST1-like catalytic activity. However, MGST1 from the microsome preparation could not form dimers as usual when exposed to reactive nitrogen species ONOO. Among the other members in MAPEG, weak expressions of leukotriene C(4) synthase (LTC(4)S) and microsomal prostaglandin E synthase 1 (mPGES-1) were observed. A stable expression of 5-Lipoxygenase activating protein (FLAP) appeared during the entire course of differentiation. MGST2 and MGST3 failed to express in the derived hepatic tissue, although mRNA of them do existed. In conclusion, ES cell-derived hepatic tissue possess MAPEG gene expression features, but not all protein expression could be detected, which helps to understand not only the nature of the tissue derived, but also the fate of bioartificial liver system, and may as well provide a valuable in vitro model for research in both inflammation process and toxic events in hepatological fields. - Source: PubMed
Zhu Dan-YanDu YueHuang XinGuo Mei-YuanMa Kui-FenYu Yong-PingLou Yi-Jia - The glutathione S-transferase (GST) gene family encodes genes that are critical for certain life processes, as well as for detoxication and toxification mechanisms, via conjugation of reduced glutathione (GSH) with numerous substrates such as pharmaceuticals and environmental pollutants. The GST genes are upregulated in response to oxidative stress and are inexplicably overexpressed in many tumours, leading to problems during cancer chemotherapy. An analysis of the GST gene family in the Human Genome Organization-sponsored Human Gene Nomenclature Committee database showed 21 putatively functional genes. Upon closer examination, however, GST-kappa 1 (GSTK1), prostaglandin E synthase (PTGES) and three microsomal GSTs (MGST1, MGST2, MGST3) were determined as encoding membrane-bound enzymes having GST-like activity, but these genes are not evolutionarily related to the GST gene family. It is concluded that the complete GST gene family comprises 16 genes in six subfamilies--alpha (GSTA), mu (GSTM), omega (GSTO), pi (GSTP), theta (GSTT) and zeta (GSTZ). - Source: PubMed
Nebert Daniel WVasiliou Vasilis