TIMP 3
- Known as:
- TIMP 3
- Catalog number:
- 30112003
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- BioTeZ
- Gene target:
- TIMP 3
Related genes to: TIMP 3
- Gene:
- TIMP1 NIH gene
- Name:
- TIMP metallopeptidase inhibitor 1
- Previous symbol:
- TIMP, CLGI
- Synonyms:
- EPO
- Chromosome:
- Xp11.3
- Locus Type:
- gene with protein product
- Date approved:
- 1986-01-01
- Date modifiied:
- 2017-07-26
Related products to: TIMP 3
102D1 TIMP-13A4 TIMP-2Anserine tissue inhibitors of metalloproteinase 3,TIMP-3ELISA KitAnserine anti - tissue inhibitors of metalloproteinase 3,TIMP-3ELISA KitAnti- TIMP-2 AntibodyAnti-Human TIMP-1Anti-Human TIMP-1Anti-Human TIMP-1Anti-human TIMP-1 (MAB), Source: Monoclonal Murine, MABAnti-human TIMP-1, bt, Source: Polyclonal bt. Rabbit, PABAnti-human TIMP-1, bt, Source: Polyclonal bt. Rabbit, PABAnti-human TIMP-1, bt, Source: Polyclonal bt. Rabbit, PABAnti-human TIMP-1, Source: Polyclonal Rabbit, PABAnti-human TIMP-1, Source: Polyclonal Rabbit, PABAnti-human TIMP-1, Source: Polyclonal Rabbit, PAB Related articles to: TIMP 3
- Over the past few years, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)- a compound from grilled or processed meats-has emerged as a major player in cancer development, especially colorectal cancer (CRC). This work dives into its potential links to CRC and uncovers the key genes that bridge this connection. - Source: PubMed
Publication date: 2026/07/23
Gao YuqiYe QianZhen YunhuanWang YanWang YiZeng YupingLiu XiaoqinZhou XiaoruChen Weiwei - Standardized molecular methods to assess the host response to breast implants are lacking. Mass spectrometry-based proteomics offers an unbiased approach to characterize the capsule proteome and the foreign-body response. - Source: PubMed
Publication date: 2026/09/10
Larsen AndreasØstergaard OleWeltz Tim KongsmarkTran John Vinh QuangBak Erik Eiler FrydshouGuðjónsdóttir Linda RegínaHemmingsen Mathilde NejrupØrholt MathiasVester-Glowinski PeterWoetmann AndersOlsen Jesper VelgaardHerly Mikkel - Buffaloes do not exhibit overt estrus signs particularly during summer, leading to a significant economic loss to farmers. Previous studies have identified several candidate transcripts (HSP70, TIMP1, TLR4 and HSD17B1), abundant in buffalo saliva during estrus stage. However, there is no widely applicable technology for estrus detection targeting these transcripts. Therefore, the present study aimed to develop reverse transcription loop mediated isothermal amplification (RT-LAMP) assays for these candidate transcripts using buffalo saliva. Saliva samples were collected from 10 cyclic buffaloes and RT-LAMP assays were optimized for salivary RNA as well as direct saliva. Among the four candidate transcripts, HSP70 showed a statistically significant colour change (p-value = 0.0191) at the estrus stage compared to the diestrus stage. This abundance of HSP70 was also supported in large simulated population datasets (10,000 animals) generated using R. Further, the RT-LAMP assays were tested using direct saliva without RNA isolation, and the colour change in the samples during estrus suggested the feasibility of estrus identification using direct saliva, overcoming the tedious step of RNA isolation. The detection of HSP70 using either direct saliva or salivary RNA indicated its potential as a marker for estrus identification. Similarly, TLR4 appeared to be another potential biomarker for RT-LAMP reaction using direct saliva, but it needs further validation in both RNA and direct saliva samples. Overall, the proof-of-concept on RT-LAMP assays optimized for salivary transcripts in the present study would be useful for estrus identification in tropical production systems following further validation on a larger sample size. - Source: PubMed
Publication date: 2026/09/08
Kaushik NikitaJoshi MansiBaithalu Rubina KumariPaul Rajani KumarSingh DheerOnteru Suneel Kumar - Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease (IBD). The role of stromal cells in UC pathogenesis is increasingly being recognized, yet their functional subsets and underlying molecular mechanisms remain poorly defined. - Source: PubMed
Publication date: 2026/09/03
Xu XiaosongDu LipengLi ZeJia XuemeiDu YaoYang QianCai Yanru - This study reports, for the first time, the establishment of endometrial organoids (EOs) from the Arabian camel (Camelus dromedarius) and evaluates their suitability as an in vitro model for embryo-maternal interactions during implantation. Endometrial tissues were collected from non-pregnant she-camels and cultured in Matrigel with a defined growth medium. By Day 7, organoids displayed a spherical morphology (200-250 µm), remained viable for up to 20 days, and expanded to approximately 1 mm. They exhibited epithelial characteristics and high proliferative activity, confirmed by expression of mucin-1, pan-cytokeratin, vimentin, and Ki67. Day 7 in vitro-produced embryos co-cultured with EOs showed significant improvements in development and trophoblast outgrowth. This was accompanied by upregulation of key developmental genes (OCT4, c-MYC, KLF4, CDX2). Cytokine profiling revealed enhanced bidirectional signaling: embryos increased secretion of CCL2, CCL4, IGF-1, IFNG, IL1α, IL12b, IL-8, LIF, IL-10, and NTF3, while EOs upregulated VEGFA, IL-8, CCL2, and TIMP1. Co-culture uniquely induced additional cytokines and amplified signaling intensity. Metabolomic analysis of embryo-conditioned medium identified 108 metabolites, including steroids associated with immunomodulation. Notably, embryos cultured in EO-conditioned medium developed up to Day 21 post-cleavage, reaching a mean diameter of 2.4 mm. Overall, camel EOs provide a physiologically relevant platform that supports embryo development and enables detailed investigation of cytokine-mediated embryo-maternal communication and implantation processes in the dromedary camel. - Source: PubMed
Publication date: 2026/09/02
Saadeldin Islam MAlqassem AlanoudAlomzyan SheemaAlmalki Reem HShinwari ZakiaHama AdelInal SahikaAbdelazim Aaser MAlaiya AyodeleRahman Anas M AbdelAwartani Khalid