AQP3 (V214) pAb host: Rabbit
- Known as:
- AQP3 (V214) pAb production species: Rabbit
- Catalog number:
- bs3671
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Bioworld
- Gene target:
- AQP3 (V214) pAb host: Rabbit
Ask about this productRelated genes to: AQP3 (V214) pAb host: Rabbit
- Gene:
- AQP3 NIH gene
- Name:
- aquaporin 3 (Gill blood group)
- Previous symbol:
- -
- Synonyms:
- GIL
- Chromosome:
- 9p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1994-07-25
- Date modifiied:
- 2019-04-23
- Gene:
- PPP1R18 NIH gene
- Name:
- protein phosphatase 1 regulatory subunit 18
- Previous symbol:
- KIAA1949
- Synonyms:
- phostensin
- Chromosome:
- 6p21.33
- Locus Type:
- gene with protein product
- Date approved:
- 2004-03-02
- Date modifiied:
- 2016-10-05
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- Aquaporins (AQPs) are integral membrane proteins that are crucial for maintaining fluid homeostasis in the female reproductive system. This study aimed to determine the immunolocalization and protein expression levels of AQP1, AQP2, AQP3, and AQP4 in rat ovaries at postnatal days 1, 5, 15, 30, and 70. AQP1 immunoreactivity was detected in the cytoplasm and nuclei of oocytes and granulosa cells in follicles on postnatal days 1, 5, and 15. It was found to increase from day 30 onward. AQP2 immunoreactivity was positive only in the zona pellucida from postnatal day 5 onward. The AQP3 immunoreaction was similar to that of AQP1, with a particularly strong reaction in smooth muscle cells located in the walls of blood vessels. AQP4 immunoreactivity was found to be strongly positive in the cytoplasm of oocytes and granulosa cells on the postnatal days examined, and this reaction was higher than that observed in theca and luteal cells. Western blot analysis revealed that AQP1 protein expression levels were high on postnatal days 30 and 70 compared with other postnatal days. These data support the idea that AQPs are local regulators of water metabolism in oogenesis, folliculogenesis, and antrum formation during postnatal development. - Source: PubMed
Alan EmelAlan AydınGram AykutLiman NarinKüçük Bayram GünerBeyaz FeyzullahKorkmaz Alev - Dilated cardiomyopathy (DCM) is the most common non-ischemic cardiomyopathy and a major cause of heart failure, but disease-specific molecular biomarkers remain limited. This study aimed to identify and prioritize tissue-level, disease-responsive candidate biomarkers for DCM using an integrative multi-omics bioinformatics framework. - Source: PubMed
Publication date: 2026/06/09
Li JingweiSong ZhongyangWang GuanweiChen YuchanCheng JiamiaoZhang Zhiming - The ruminant colon plays a critical role in intestinal homeostasis but is highly susceptible to dysfunction induced by high-concentrate diets during the finishing period. This study investigated the efficacy of alkaline mineral complex (AMC) against such colonic disturbances in finishing cattle. - Source: PubMed
Publication date: 2026/06/02
Li JiaLiu XingyuGu LiLiu XiaowanWang YixinGuo HongruiGou LipingQi JianchengZuo Zhicai - Adolescent depression is a prevalent and serious mental health issue that can negatively impact multiple organ systems, including the cardiovascular system. This study investigates the effects of chronic unpredictable mild stress (CUMS), a validated animal model of depression, on the expression of Aquaporins (AQP1, AQP2 and AQP3) in the cardiac tissue of adolescent rats and evaluates the potential therapeutic role of ashwagandha (Withania somnifera (L.) Dunal). Twenty-eight male Wistar albino rats were divided into four groups: Control, CUMS, CUMS+SERT, and CUMS+ASHW. Treatments were administered via oral gavage for 28 days, and cardiac tissues were evaluated histologically, immunohistochemically and biochemically. While serum levels of CK, Na, Cl and K showed no significant differences across groups, histological examination revealed myocardial damage (edema, hemorrhage, vacuolization) in CUMS rats. Immunohistochemical analysis demonstrated strong AQP1 expression across all groups, while AQP2 and AQP3 showed increased expression in treatment groups compared to the control. These findings suggest that Ashwagandha may mitigate stress-induced cardiac changes and influence aquaporin expression, particularly AQP2 and AQP3, which could be relevant to cardiac water balance and function in depression. Further studies are warranted to explore the molecular mechanisms linking aquaporin modulation and cardioprotection in stress-related pathologies. - Source: PubMed
Publication date: 2026/06/15
Baksi NGokdemir G ŞArkaş Alklay AKarakoç Z - Constipation is a common gastrointestinal disorder, which impairs health and quality of life. This study evaluated the ameliorating effects and underlying mechanism of 6'-sialyllactose (6'-SL) and subsp. BB12 (BB12) on loperamide-induced constipation and associated depression-like behaviors. 6'-SL combined with BB12 increased the fecal water content, fecal pellet number, and gastrointestinal transit rate while reducing the time of first black feces. 6'-SL and BB12 modulated secretion of intestinal neurotransmitters, regulated expression of AQP3 and Claudin-1, and modulated expression of key proteins in the SCF/c-Kit pathway. Meanwhile, 6'-SL and BB12 ameliorated depression-like behaviors by inhibiting inflammatory responses and modulating the expression of synaptic plasticity-related proteins in the brain. Moreover, 6'-SL and BB12 regulated the diversity of gut microbiota, enhanced the relative abundance of and , and elevated SCFA levels. This study provides a theoretical and practical basis for developing functional foods based on synbiotics containing 6'-SL and BB12. - Source: PubMed
Publication date: 2026/06/15
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