SHBG ELISA
- Known as:
- SHBG Enzyme-linked immunosorbent assay test
- Catalog number:
- kapd2996
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Diasource
- Gene target:
- SHBG ELISA
Related genes to: SHBG ELISA
- Gene:
- SHBG NIH gene
- Name:
- sex hormone binding globulin
- Previous symbol:
- -
- Synonyms:
- ABP, TEBG, MGC126834, MGC138391
- Chromosome:
- 17p13.1
- Locus Type:
- gene with protein product
- Date approved:
- 1990-03-14
- Date modifiied:
- 2016-04-04
Related products to: SHBG ELISA
Related articles to: SHBG ELISA
- Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder in which hyperandrogenism represents a centralpathophysiological feature. Increasing attention has been directed toward chronic inflammatory factors that may modulate androgenexcess. Helicobacter pylori (H. pylori) infection is a prevalent chronic bacterial infection associated with systemic low-grade inflammation.However, its potential relationship with androgen-related hormonal parameters in PCOS remains poorly explored. - Source: PubMed
Wutke-Ostręga JoannaSzul MateuszPluta Dagmara - Low circulating testosterone in physically stressed populations is frequently interpreted as evidence of hypogonadism or intrinsic gonadal dysfunction. However, convergent data from military field studies, endurance athletes, and competitive stress models demonstrate that testosterone suppression during sustained stress is commonly a centrally mediated, reversible adaptation rather than intrinsic testicular failure. Severe energy deficit, sleep disruption, and uncontrollable psychogenic stress suppress hypothalamic gonadotropin-releasing hormone and luteinizing hormone pulsatility, reduce testicular androgen production, and frequently increase sex hormone-binding globulin (SHBG), thereby disproportionately lowering free testosterone. Human chorionic gonadotropin stimulation studies confirm preserved Leydig cell responsiveness under these conditions, supporting hypothalamic-pituitary inhibition as the dominant mechanism. In contrast, high mechanical loading in resistance-trained men does not suppress basal testosterone when energy availability is maintained, underscoring energetic sufficiency, not exercise modality, as the principal determinant of androgen tone. Acute competitive stress produces rapid, appraisal-dependent modulation of testosterone independent of SHBG, further demonstrating central regulation. Across contexts, androgen suppression tracks energetic and psychological constraint and is reversible with restoration of energy balance and recovery. Recognition of this adaptive endocrine phenotype is essential to distinguish functional central suppression from pathological hypogonadism and to guide appropriate clinical evaluation. - Source: PubMed
Publication date: 2026/04/27
Friedl Karl ENindl Bradley CPotter Adam W - This study reviews the main candidate genes involved in the pathophysiology of Polycystic Ovary Syndrome (PCOS). PCOS is a common endocrine-metabolic disorder in women of reproductive age, characterized by menstrual irregularity, hyperandrogenism, and polycystic ovarian morphology. It is associated with increased metabolic and cardiovascular risk and is a leading cause of infertility. Although its pathophysiology is not fully understood, alterations in the hypothalamic-pituitary-ovarian axis, insulin metabolism, and steroidogenesis have been described. Polymorphisms in genes encoding hormones, enzymes, and receptors in these pathways contribute to clinical variability and ethnic differences, offering potential for early diagnosis and personalized medicine. This review summarizes key candidate genes related to insulin metabolism (INS, INSR, IRS-1), the hypothalamic-pituitary-ovarian axis (LHβ, LHCGR, FSHR, GnRHR, AMH, AMHR2, KISS1, CAPN10), steroidogenesis (CYP11A, CYP17A1, CYP19A1, CYP21, 17β-HSD, SHBG, AR, STAR), and other clinically relevant mechanisms such as obesity, lipid metabolism (PPARG, VDR, FTO), and follicular development (ACE). - Source: PubMed
Publication date: 2026/04/19
Cepero-González María de Los AngelesAguilar-Galarza AdrianaRodríguez-García Víctor ManuelGarcía-Gasca TeresaMoreno Celis Ulisses - Female reproductive hormonal fluctuations may be influenced by lifestyle behaviors such as diet, physical activity (PA), and sleep. However, little is known about these interactions over time or how they may differ between naturally menstruating (NM) and hormonal contraceptive (HC) women. This 8-wk observational study examined relationships between hormone levels and dietary intake, PA, exercise, and sleep quality, and explored differences by menstrual cycle phase and contraceptive status. - Source: PubMed
Publication date: 2026/04/22
Aguiar Bonfim Cruz Ariel JChandler Alexa JIrwin Gena LSchwartz MalaynaFrost Ann - To investigate the levels of the triglyceride-glucose (TyG) index and sex hormone-binding globulin (SHBG) in patients with type 2 diabetes mellitus (T2DM) with diabetic retinopathy (DR), and to explore their correlations with biochemical parameters and the homeostasis model assessment of insulin resistance (HOMA-IR) in DR patients. - Source: PubMed
Publication date: 2026/05/18
Zhang MinZhou Xin-RuiMa Wei-GuoYin Xiao-HongLi YaLi Rong