WDR16 antibody
- Known as:
- WDR16 (anti-)
- Catalog number:
- orb100177
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Biorbyt biorb
- Gene target:
- WDR16 antibody
Related genes to: WDR16 antibody
- Gene:
- CFAP52 NIH gene
- Name:
- cilia and flagella associated protein 52
- Previous symbol:
- WDR16
- Synonyms:
- WDRPUH, FLJ37528
- Chromosome:
- 17p13.1
- Locus Type:
- gene with protein product
- Date approved:
- 2001-07-16
- Date modifiied:
- 2014-11-19
Related products to: WDR16 antibody
Related articles to: WDR16 antibody
- 1. Despite the pivotal role of the hypothalamic-pituitary-gonadal (HPG) axis in avian reproduction, the underlying molecular mechanisms that govern sexual maturity and spermatogenesis in roosters are not well elucidated. This study aimed to explore gene expression changes in the HPG axis using Wenchang cockerels.2. Phenotypic results showed significant testicular growth from 18 to 20 weeks of age. Transcriptome analyses identified 2,154 differentially expressed genes (DEG) in testes, which was markedly higher than those identified in hypothalamus (52 DEG) and pituitary (27 DEG).3. Functional enrichment analysis showed neuroactive ligand-receptor interactions and hormone transport pathways in the hypothalamus and pituitary and ciliary motility and spermatogenesis pathways in the testes.4. Protein-protein interaction (PPI) networks analysis pinpointed key hub genes, such as , , , , , and , associated with spermatogenesis and sperm motility.5. This research gave insights into the genetic regulatory networks within the HPG axis that orchestrate testicular development and maturation in roosters, paving the way for potential applications in the molecular breeding of breeding roosters for reproductive optimisation. - Source: PubMed
Publication date: 2026/08/19
Liu YAzim SLi JZhang BZhang ZLuo XSu CLiu XFeng Y - To describe a cohort of fetuses with abnormal prenatal findings in whom exome sequencing (ES) identified genetic diagnoses that refined prognostic assessment and reduced prognostic uncertainty. - Source: PubMed
Publication date: 2026/08/16
Rips JonathanMor-Shaked HagarBirnbaum RivkaEilat AvitalGoldwicht NataliePorat ShayErlik UriBenyamini LilachDaum Hagit - We report a 2-year-old boy with a homozygous CFAP52 mutation presenting with situs inversus totalis, severe epileptic developmental encephalopathy, and global developmental delay, expanding the phenotypic spectrum of CFAP52-related ciliopathies. Clinical findings included multifocal epileptiform discharges, thin corpus callosum, and a small subdural hematoma. Trio whole-exome sequencing also revealed a homozygous NCAPG2 variant of uncertain significance, however, its clinical significance remains unproven and no causal relationship can be established. This case highlights the diagnostic value of comprehensive genomic testing in complex neuro-visceral disorders and underscores the importance of cautious interpretation of co-inherited variants in atypical ciliopathy presentations. The report follows CARE guidelines. - Source: PubMed
Publication date: 2026/07/19
Hetta Anwar AbuAbughaboosh LinaAl-Qasrawi JenanAmro BalqeesAlshaer Mayar - Esophageal squamous cell cancer (ESCC) is one of the most common and lethal malignancies. It is urgent to uncover the underlying mechanisms for ESCC progression. Aberrant DNA methylation is observed in ESCC. However, the precise relationship between DNA methylation alterations and clinical features of ESCC is still largely unknown. We aimed to further explore the potential role of DNA methylation in the development of ESCC. - Source: PubMed
Publication date: 2025/11/10
Wang GuangchaoLv MengzhuWang YanZhan Qimin - The testis, a critical reproductive organ in male animals, is responsible for sperm production and androgen secretion. Testis weight often correlates with reproductive performance, yet the genetic factors influencing testicular traits in chickens remain unclear. - Source: PubMed
Publication date: 2025/05/27
Ma Jing-EHuang KeGibril Bahareldin Ali AbdallaXiong XinweiWu YanpingWang ZhangfengXu Jiguo