FAIM1 antibody
- Known as:
- FAIM1 (anti-)
- Catalog number:
- orb100197
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Biorbyt biorb
- Gene target:
- FAIM1 antibody
Related genes to: FAIM1 antibody
- Gene:
- FAIM NIH gene
- Name:
- Fas apoptotic inhibitory molecule
- Previous symbol:
- -
- Synonyms:
- FLJ10582, FAIM1
- Chromosome:
- 3q22.3
- Locus Type:
- gene with protein product
- Date approved:
- 2002-05-29
- Date modifiied:
- 2016-10-05
Related products to: FAIM1 antibody
Related articles to: FAIM1 antibody
- : Of the approximately 8% of children in the United States (US) with food allergy (FA), roughly 40% report allergy to multiple foods. The ubiquity and intensity of FA management can impose psychosocial burdens on both pediatric patients and caregivers, which may be exacerbated among those allergic to multiple foods. However, little work has comprehensively estimated the burden of multi-FA in heterogeneous pediatric populations with clinically confirmed FA. : Children with allergist-diagnosed, IgE-mediated FA were enrolled in the FORWARD multisite prospective cohort study. Psychosocial burden was assessed annually using the FA Quality of Life Questionnaire-Parent Form 10 (FAQL-PF10) and FA Independent Measure-Parent Form (FAIM-PF); psychosocial burden for caregivers was measured with the FA Quality of Life-Parental Burden (FAQL-PB) Questionnaire. Multilevel regression models estimated independent effects of the number of current FAs after adjusting for child age, gender, race, ethnicity, household income, caregiver education, atopic comorbidities, and recruitment site. : FA-related psychosocial burden increased linearly for patients and caregivers with each additional FA even after controlling for demographic factors such as age, gender, race, ethnicity, income, education, and other atopic conditions, as well as repeated observations within participants: FAQL-PF10 B = 0.082 ( = 2206; = 0.004), FAIM-PF B = 0.152 ( = 2206; < 0.001), and FAQL-PB B = 0.166 ( = 1081; < 0.001). : The psychosocial burden of pediatric FA increases monotonically with each additional current FA, highlighting opportunities for tailored psychosocial, behavioral, and pharmacologic interventions to improve FA-related outcomes among those most impacted. - Source: PubMed
Publication date: 2026/05/29
Cay MariesaOnal CaglarHerbert LindaEngel MelissaSharma HemantMahboobeh MahdaviniaAssa'ad AmalMoy JamesBilaver LucyGupta RuchiWarren Christopher - Inadequate water, sanitation, and hygiene (WASH) services in healthcare facilities (HCFs) put patients and HCF staff at risk of healthcare-associated infections. To facilitate continuous improvements of WASH services in Zimbabwe, the Water and Sanitation for Health Facility Improvement Tool (WASH FIT) program was implemented in 100 HCFs from August 2021 to May 2023. A qualitative study was conducted to describe the experiences and perceptions of WASH FIT implementation by HCF staff and government officers in four provinces of Zimbabwe through in-depth interviews. The findings revealed that WASH FIT has been recognized as a practical methodology, which can contribute to increasing WASH service availability, patient and staff satisfaction, and health service utilization. Constraints on financial resources, supplies, and personnel time and skills were noted as key implementation challenges. This study also highlighted that training might not have been adequate for HCF staff to fully internalize the methodology and five steps of WASH FIT. By mobilizing continuous and adequate financial resources and conducting adequate training for HCF teams, HCFs may further enhance the ownership and sustainability of WASH FIT implementation. - Source: PubMed
Publication date: 2026/06/07
Hirai MitsuakiMartinsen AndreaMwenda JohnNzara BonifaceRajasingham AnanguChivasa MillitonHandireketi NewtenMavi TariroShirihuru NesbertZinyandu EddingtonNkomo Witness MSibanda SilindileKushner CindyNyamandi VictorMidzi NicholasHandzel Thomas - Postnatal skeletal muscle growth in poultry relies on the precise orchestration of skeletal muscle satellite cell (SMSC) fate, yet the regulatory non-coding RNA networks governing this process remain partially veiled. Integrating small RNA sequencing with developmental expression profiling, we identified miR-6553-3p as a key differentially expressed regulator. Functional assays showed that miR-6553-3p markedly reduced SMSC proliferation while promoting myogenic differentiation. Specifically, miR-6553-3p significantly suppressed PAX7 expression at both the mRNA and protein levels, while simultaneously upregulating the mRNA and protein levels of MYOG and MYH1. Mechanistically, dual-luciferase assays confirmed that miR-6553-3p directly targeted Fas Apoptotic Inhibitory Molecule (FAIM). As an indispensable regulator of cellular homeostasis and cell fate decisions, FAIM is known to modulate key signaling cascades such as PI3K/AKT. In this study, we showed that FAIM normally sustained the proliferative pool of SMSCs; however, its repression by miR-6553-3p effectively attenuated AKT phosphorylation, linking this miRNA specifically to the PI3K/AKT pathway. By characterizing the miR-6553-3p-FAIM-AKT axis, our findings provide a molecular basis for fine-tuning muscle development and enhancing production traits during the critical early post-hatch window in the poultry industry. - Source: PubMed
Publication date: 2026/05/28
Hu ZhiGuo LonggeXu HengyongYang TingChen JiapengYang ShiyuLiu YipingWang Yan - We devise and experimentally validate a theoretical model to account for lost photon counts during the exposure time of a time-correlated single photon counting (TCSPC)-based QuantICAM single photon avalanche diode array camera. The work is motivated by the quest for TCSPC-based wide-field time-resolved fluorescence anisotropy imaging (TR-FAIM), implemented by the acquisition of images at orthogonal polarization. For accurate, quantitatively correct TR-FAIM, the two images must be acquired under equivalent conditions and any photons lost during the camera exposures must be precisely quantified. Our model is based on a binomial distribution with a single adjustable parameter. We plot the recorded versus the true photon counts for exposure times of 250 s and 1000 s, using photons with random arrival times and from fluorescence decays. Our model describes the experimental data well and the correct number of excitation cycles during the exposure time is extracted from least-squares fits of the binomial model to the experimental data. On the basis of this model, we account for lost photons in TCSPC-based TR-FAIM and show that a compensation for lost photons is essential to obtain quantitatively correct steady-state anisotropy and-factor histograms in TR-FAIM. We also show that, under the conditions used, the rotational correlation time, initial anisotropyand hindered rotation parameterr∞histograms are only marginally affected by lost photons. Our work thus paves the way for robust and reliable TCSPC-based TR-FAIM. - Source: PubMed
Publication date: 2026/05/27
Obeid Mogridge LouisNedbal JakubGyongy IstvanHenderson Robert KSuhling Klaus - The new "Passerelle" program aims to reduce socioeconomic inequalities in diet in France, by offering an untargeted cash transfer (CT) coupled with social guidance to households in precarious situations. - Source: PubMed
Publication date: 2026/04/29
Gallinari-Safar PierreEymard-Duvernay SabrinaDubois ChristopheDarmon NicoleSomaraki MariaHulot MassimoSouchereau ClaraMartin EmilieOllivier EmmanuelQuéau HélèneGosset VigdisPerignon Marlène