SSBP2 antibody
- Known as:
- SSBP2 (anti-)
- Catalog number:
- orb100324
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Biorbyt biorb
- Gene target:
- SSBP2 antibody
Related genes to: SSBP2 antibody
- Gene:
- SSBP2 NIH gene
- Name:
- single stranded DNA binding protein 2
- Previous symbol:
- -
- Synonyms:
- HSPC116
- Chromosome:
- 5q14.1
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-14
- Date modifiied:
- 2016-03-18
Related products to: SSBP2 antibody
Related articles to: SSBP2 antibody
- Myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions (M/LN-eo-TK) are diverse, with most cases showing a combination of lymphoblastic leukemia/lymphoma and myeloproliferative features. Various tyrosine kinase fusion genes have been identified, including FLT3 fusions. RNA based next generation sequencing studies offer an effective approach to detect such pathogenic fusion genes, including the novel SSBP2::FLT3 fusion described here. Timely identification of this fusion gene led to targeted management of our patient, who achieved complete resolution of his FDG-avid lymphadenopathy only after the addition of gilteritinib. Two years after successful bone marrow transplant, the patient remains in complete remission. Clinicians and pathologists should have a low index of suspicion for a M/LN-eo-TK when evaluating patients with and without unexplained eosinophilia in the context of extramedullary lymphoid or myeloid disease or unusual myeloproliferative disorders. - Source: PubMed
Publication date: 2026/05/22
Cook James RAstbury CarolineBosler David SMolina John CRogers Heesun JSobecks Ronald MOwczarczyk Anna B - To investigate the clinical characteristics and prognosis of childhood acute lymphoblastic leukemia (ALL) with rearrangement. - Source: PubMed
Tao Ye-QingCui Ding-DingJia Xiao-PeiLian An-NaQi Wen-JingZhu PingWang Chun-MeiSheng Guang-Yao - Dasatinib is increasingly used in the treatment of pediatric acute lymphoblastic leukemia (ALL) for its potent efficacy. However, the specific spectrum and incidence of adverse reactions attributable to it remain incompletely defined in the pediatric population. This retrospective cohort study aims to clarify the safety profile of dasatinib by directly comparing the incidence and types of adverse reactions between pediatric ALL patients who received dasatinib and those who did not. - Source: PubMed
Publication date: 2025/11/26
Yu Li-TingXue QiangFeng QianWang ZhuoZhang Shun-GuoGu Jian-Ping - Uterine carcinosarcoma is a rare gynecological malignancy characterized by high invasiveness and poor prognosis. At present, common treatment methods include surgery, chemotherapy, and radiotherapy. Radiotherapy can induce tumor cells to produce reactive oxygen species through ionizing radiation, leading to damage to intracellular DNA and mediating tumor cell death. Based on this, we identified a novel radiotherapy sensitive gene for predicting the prognosis, immune microenvironment, and drug sensitivity of uterine carcinosarcoma patients. - Source: PubMed
Zhou YingCui RanLei DaGao Shun - Lupus nephritis (LN) represents a major complication in systemic lupus erythematosus (SLE). The objective of this study was to evaluate the TRIM8 gene and its associated non-coding RNAs (lnc-SSBP2-1:1 and hsa-miR-126-5p) as potential non-invasive biomarkers for LN activity. - Source: PubMed
Publication date: 2025/11/05
Elgawad Mostafa Abdelnasier AbdShinnawy Howayda Abdelhamid ElEissa SanaaAli Nouran Abdelfattah SayedBehairy Maha AbdelmoneimKamel Cherry RedaKamel Marwa Mostafa