PAGE1 antibody
- Known as:
- PAGE1 (anti-)
- Catalog number:
- orb100353
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Biorbyt biorb
- Gene target:
- PAGE1 antibody
Related genes to: PAGE1 antibody
- Gene:
- PAGE1 NIH gene
- Name:
- PAGE family member 1
- Previous symbol:
- GAGEB1
- Synonyms:
- PAGE-1, GAGE-9, CT16.3
- Chromosome:
- Xp11.23
- Locus Type:
- gene with protein product
- Date approved:
- 1999-04-15
- Date modifiied:
- 2015-11-18
Related products to: PAGE1 antibody
Related articles to: PAGE1 antibody
- Hepatocellular carcinoma (HCC) develops in a chronically hypoxic microenvironment; however, the contribution of hypoxia-regulated long non-coding RNAs (lncRNAs) remains poorly defined. - Source: PubMed
Publication date: 2026/06/15
Hacioglu NelinDulger Aylin TurkogluKoc Sevin AvsarTokay EsraAlper MeltemKockar Feray - Technology-facilitated child sexual exploitation and abuse (TF-CSEA) represents a growing global threat, with over 300 million children affected worldwide. While research has documented severe psychological consequences of victimisation, specific mental health vulnerabilities that can be associated with increased likelihood of TF-CSEA remain poorly understood, limiting prevention efforts. - Source: PubMed
Publication date: 2026/04/10
Page SabrinaNotté EvaGeorge HannaSlater CarleighCagney JackIlyas IqraRozubi Norsayyidatina CheAnderson KimberleyRamaiya AsthaFry Debi - Spinal epidural abscess is a rare but serious condition with poor outcomes. It's classic triad of new back pain, neurological deficit and fever is only present in 15% of cases at presentation and is initially misdiagnosed in 75-89%. Delaying treatment is associated with worse outcomes. Delirium is itself a risk factor for mortality but the disturbance in cognition and memory can also complicate clinical assessment. We present a case of delirium caused by, and obscuring, a spinal epidural abscess. This case highlights the difficulties in diagnosing spinal epidural abscesses, the need for a high index of suspicion for the condition and timely action to minimise morbidity. In addition, it demonstrates the value of treating unexplained delirium as an emergency and the danger of diagnostic premature closure. Finally, the importance of persistent clinical examination of the confused and non-cooperative patient. - Source: PubMed
Publication date: 2024/05/04
Page BenjaminWaddy Sam - N1-methyladenosine (mA), among the most common internal modifications on RNAs, has a crucial role to play in cancer development. The purpose of this study were systematically investigate the modification characteristics of mA in hepatocellular carcinoma (HCC) to unveil its potential as an anticancer target and to develop a model related to mA modification characteristics with biological functions. This model could predict the prognosis for patients with HCC. - Source: PubMed
Publication date: 2024/04/22
Wu YingminLi LianWang LongZhang ShenjieZeng ZhiruiLu JieyuWang ZhiZhang YeweiZhang ShilongLi HaiyangChen Tengxiang - Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous cancer, with minimal response to therapeutic intervention and with 85% of cases diagnosed at an advanced stage due to lack of early symptoms, highlighting the importance of understanding PDAC immunology in greater detail. Here, we applied an immunoproteomic approach to investigate autoantibody responses against cancer-testis and tumor-associated antigens in PDAC using a high-throughput multiplexed protein microarray platform, comparing humoral immune responses in serum and at the site of disease in order to shed new light on immune responses in the tumor microenvironment. We simultaneously quantified serum or tissue IgG and IgA antibody isotypes and subclasses in a cohort of PDAC, disease control and healthy patients, observing inter alia that subclass utilization in tumor tissue samples was predominantly immune suppressive IgG4 and inflammatory IgA2, contrasting with predominant IgG3 and IgA1 subclass utilization in matched sera and implying local autoantibody production at the site of disease in an immune-tolerant environment. By comparison, serum autoantibody subclass profiling for the disease controls identified IgG4, IgG1, and IgA1 as the abundant subclasses. Combinatorial analysis of serum autoantibody responses identified panels of candidate biomarkers. The top IgG panel included ACVR2B, GAGE1, LEMD1, MAGEB1 and PAGE1 (sensitivity, specificity and AUC values of 0.933, 0.767 and 0.906). Conversely, the top IgA panel included AURKA, GAGE1, MAGEA10, PLEKHA5 and XAGE3aV1 (sensitivity, specificity, and AUC values of 1.000, 0.800, and 0.954). Assessment of antigen-specific serum autoantibody glycoforms revealed abundant sialylation on IgA in PDAC, consistent with an immune suppressive IgA response to disease. - Source: PubMed
Publication date: 2024/02/21
Maimela Pamela Winnie MSmith MuneerahNel Andrew J MBernam Suba Dharshanan PJonas Eduard GBlackburn Jonathan M