CKAP5 antibody
- Known as:
- CKAP5 (anti-)
- Catalog number:
- orb101634
- Product Quantity:
- EUR
- Category:
- -
- Supplier:
- Biorbyt biorb
- Gene target:
- CKAP5 antibody
Related genes to: CKAP5 antibody
- Gene:
- CKAP5 NIH gene
- Name:
- cytoskeleton associated protein 5
- Previous symbol:
- -
- Synonyms:
- ch-TOG, KIAA0097, TOG, TOGp
- Chromosome:
- 11p11.2
- Locus Type:
- gene with protein product
- Date approved:
- 2005-06-01
- Date modifiied:
- 2014-11-19
Related products to: CKAP5 antibody
Related articles to: CKAP5 antibody
- The ovary is a central female reproductive organ responsible for producing oocytes and secreting steroid hormones. To investigate the molecular similarities and potential evolutionary origins of the ovary across vertebrates, we integrated publicly available single-cell and single-nucleus transcriptomic data from nine species, including oviparous animals (fish and chicken) and viviparous mammals (mouse, rat, sheep, goat, yak, monkey, and human). - Source: PubMed
Publication date: 2026/04/14
Xue BailingLiu YajingZhou ChenDossybayev KairatBaatar NarantuyaYudin NikolayZhang LinweiYang JiLi MenghuaXu Songsong - Prothrombin gene mutations can be associated with either a thrombotic or a bleeding risk. Genomic studies and coagulation workup can provide valuable information to better understand their clinical importance. - Source: PubMed
Publication date: 2026/02/02
Siegemund AnnelieSiegemund ThomasBönigk HagenSchlosser KristinaKonn KatjaKeil SabinePetros Sirak - Esophageal squamous cell carcinoma (ESCC) is a common and aggressive malignancy. N-acetyltransferase 10 (NAT10) has been implicated as an oncogenic promoter in ESCC. This study aimed to explore the molecular mechanisms through which NAT10 exerts its oncogenic functions in this malignancy. - Source: PubMed
Publication date: 2026/02/24
Wei WenxueWei LiZhu AnkangZhang YijunYao WenjianLiu MengboLin Xing - Cancer cell characteristics are determined by gene expression, influenced by genomic, epigenetic, and transcriptional modifications. Genomic rearrangements and transcriptional splicing can result in the formation of fusion genes. BCR-ABL1 is an established fusion gene employed as a biomarker in leukemia. A single gene can amalgamate with several other genes and may impact cellular fate. Ethnicity-specific variants of fusion genes have been identified, such as the TMPRSS2-ERG variation observed in prostate malignancies among African-American, Caucasian, and Japanese populations in research studies. Next-generation sequencing has provided a new method for predicting genomic and transcriptomic changes. We aim to identify fusion genes in the Indian population using cancer samples to enhance diagnostic outcomes. This study performed a meta-analysis of tumor-specific RNA sequencing data for liver, tongue, and ovarian cancers, which are available online. It identified known fusion genes, including TRO-MAGED2, KRT14-S100A9, RNASE10-CD38, ACTN4-ACTN1, RGPD1-RANBP2, CTSC-RAB38, C15orf57-CBX3, AMBRA1-CKAP5, ATP2B3-ATP2B4, CNKSR3-IPCEF1, E2F4-RPL14, and MZT2A-MZT2B, along with 101 novel fusion genes. Novel fusion genes GABRP_SCGB3A2 and WWOX_FUT1 were identified in all three tumor tissues. GABRP acts as a tumor inducer, whereas SCGB3A2 functions as a tumor suppressor. WWOX2 serves as a tumor suppressor, whereas FUT1 functions as a promoter of malignancy. The interplay between tumor inducers and suppressors may serve as a survival mechanism for cancer cells, a subject that has received limited research attention. - Source: PubMed
Publication date: 2026/02/09
Yadav RahulKhan HafsaSingh PoonamKumar PramodKumar Singhal Dinesh - Liver hepatocellular carcinoma (LIHC) remains a leading cause of cancer-related mortality worldwide, with limited therapeutic options for advanced stages. Cytoskeleton-associated protein 5 (CKAP5), a key regulator of microtubule dynamics, has emerged as a potential oncogene in multiple cancers, yet its precise role and clinical relevance in LIHC pathogenesis and tumor immunity are not fully understood. - Source: PubMed
Publication date: 2025/12/23
Liao LushengLi YawenWei BixiaoFei MeiHuang FengdieHuang YuejiaoHu YuhongXiao ShanshanDong MingyouLong Qinqin