CD95 _ Fas
- Known as:
- CD95 _ Fas
- Catalog number:
- 11-362-C025
- Product Quantity:
- 0.025 mg
- Category:
- -
- Supplier:
- Exbio
- Gene target:
- CD95 _ Fas
Related genes to: CD95 _ Fas
- Gene:
- FAS NIH gene
- Name:
- Fas cell surface death receptor
- Previous symbol:
- FAS1, APT1, TNFRSF6
- Synonyms:
- CD95, APO-1
- Chromosome:
- 10q23.31
- Locus Type:
- gene with protein product
- Date approved:
- 1992-06-25
- Date modifiied:
- 2019-04-23
Related products to: CD95 _ Fas
Related articles to: CD95 _ Fas
- This study examined the effects of dietary crude protein (CP) level and starch: fat ratio (SFR) on glucose and lipid metabolism in geese. A total of 360 male Jiangnan White geese were allocated to a 3 × 2 factorial arrangement with two CP levels (14.5% and 16.5%) and three SFRs (SFR, SFR, and SFR) from 28 to 63 days of age. Under the low-protein condition, Both the SFR and SFR group enhanced body weight of geese at 63 d, but SFR increased subcutaneous and abdominal fat deposition. Dietary SFR changed liver cholesterol metabolism and glycogen content, while CP levels mainly affected the activity of enzymes related to liver glucose and lipid metabolism: 14.5% CP increased AMPK and ACC activity, but decreased FAS, CS and G6PC activity. Both CP level and SFR altered muscle fatty acid composition, but the effect of SFR was usually more significant. An SFR of 11:1 was beneficial for improving the muscle fatty acid profile. Gene expression analysis further revealed that low protein compensatorily regulated liver energy metabolism, while excessive fat in low SFR diets led to lipid metabolism disorders. In conclusion, optimizing the energy structure of low-protein diets, especially by maintaining a medium SFR (11:1), could improve glucose and lipid metabolism in geese while increasing body weight. - Source: PubMed
Publication date: 2026/05/22
Zheng XuchengShen JieYang ZhiWang WeiLi XuanYang HaimingWang Zhiyue - Excess zinc (Zn) has an important effect on seed yield and quality, as well as the possibility of subsequent processing. In this study, we investigated the effect of excess Zn concentrations (50, 100, and 150 mg kg) in the substrate on the seed yield and selected biochemical parameters of white mustard ( L.) seeds. The following parameters were investigated: seed yield, individual lipid classes were analyzed using high-performance thin-layer chromatography (HPTLC); gas-liquid chromatography with mass-selective detection (GS-MS) was used to analyze the fatty acid (FA) profile; and trace elements were detected using inductively coupled plasma-mass spectrometry (ICP-MS). It was found that Zn at concentrations of 100 and 150 mg kg caused a decrease in the number of pods, and the 1000-seed weight also decreased at a Zn concentration of 150 mg kg. The Zn concentration in seeds from plants grown on contaminated substrate was higher than the control values and government standard thresholds. Zn at concentrations of 100 and 150 mg kg caused a slight increase in the content of triacylglycerols (up to 1.35-1.36% dry weight) and the total content of unsaturated FAs along with a decrease in saturated and total FAs. Zn at a concentration of 50 mg kg stimulated an increase in the total FA content. A high erucic acid content in seeds was observed in all studied variants. A mathematical model was used to evaluate the physicochemical properties of biofuels. The parameters relating to the FA composition of seeds of plants grown on a Zn-contaminated substrate did not deteriorate, and in the case of the kinematic viscosity coefficient, they were even improved compared to the control plants and complied with American (ASTM D6751) and European (EN 14214) standards for biofuels. The obtained data indicate a negative effect of high Zn concentrations on seed yield. Changes in the FA composition of seeds may reduce their value for the production of edible oils due to the high content of erucic acid, but they could be used to produce technical oils (biofuel). - Source: PubMed
Publication date: 2026/06/09
Repkina NataliaMurzina Svetlana AVoronin Viktor PBatova YuliaIkkonen ElenaAntonova Ekaterina - Controlled comparisons of extracellular β-hydroxybutyrate (β-HB) responses induced by individual dietary fatty acids (FAs) remain limited. This study established a preliminary hepatocyte-derived in vitro assay for comparing FA-associated β-HB responses and used exploratory descriptor-based modeling for hypothesis-generating FA ranking. - Source: PubMed
Publication date: 2026/06/21
Liu XiaojingPan FeiWang YandanWei WeiJin JunWang XingguoCui Zhe - : The impact of orthodontic appliances on oral health-related quality of life (OHRQoL) has gained increasing attention, particularly in relation to patient-centered outcomes. Clear aligners (CAs) are often perceived as more comfortable than fixed appliances (FAs), although evidence remains limited and heterogeneous. This systematic review and meta-analysis aimed to compare the effects of CAs and FAs on OHRQoL in patients with Angle class I malocclusion and to further evaluate the reliability of the findings using trial sequential analysis (TSA). : This review followed PRISMA guidelines and was registered in PROSPERO (CRD420251051003). A comprehensive search of PubMed, Scopus, Web of Science, Embase, and Cochrane CENTRAL was conducted. Only randomized controlled trials comparing CAs and FAs and reporting OHRQoL outcomes (OHIP-14) were included. Random-effects meta-analyses were performed on early changes in OHRQoL. TSA was applied to control for type I and II errors and to evaluate the sufficiency of the cumulative evidence. : Two randomized controlled trials (n = 74) were included in the quantitative synthesis. Both treatments were associated with a transient deterioration in OHRQoL after appliance placement. Meta-analysis showed statistically significant improvements favoring CAs in psychological discomfort ( = 0.007) and psychological disability ( < 0.001), while no significant differences were observed for other domains or for overall OHRQoL. Exploratory TSA suggested an early signal in favor of psychological outcomes, with the cumulative Z-curve crossing the monitoring boundary; however, given the very small number of included trials, these findings should be regarded as preliminary and hypothesis-generating rather than confirmatory. In contrast, for most other outcomes, the required information size was not reached and results remained inconclusive. For handicap, TSA suggested that a clinically relevant difference is unlikely. : Clear aligners may provide a modest short-term advantage over fixed appliances in psychological aspects of OHRQoL, while no consistent differences are observed in physical or overall domains, based on very limited evidence. TSA suggests a preliminary signal in psychological outcomes but highlights insufficient evidence for most other domains. These results should be interpreted with caution, and further high-quality randomized trials are needed. - Source: PubMed
Publication date: 2026/06/04
Lalli ElisabettaCaramaschi ElenaNieri AgneseVitale SaraLedda MaurizioPorcu GiuliaDelogu Pier LuigiVerdecchia AlessioSpinas Enrico - Lipophorin receptors play a crucial role in the reproductive development of insects. However, their regulatory function in insect reproductive diapause remains poorly understood. In this study, a lipophorin receptor gene () was cloned from using RT-PCR. The open reading frame (ORF) of is 2589 bp in length, encoding 862 amino acids, and possesses typical structural characteristics of the lipophorin receptor family. RT-qPCR analysis indicated that the expression of is up-regulated in adults before diapause, exhibits an expression pattern of initial down-regulation, subsequent up-regulation, and then further down-regulation during diapause, and is up-regulated again after diapause termination. After RNA interference of , the expression levels of diapause-related genes ecdysone receptor (), nuclear hormone receptor (), and vitellogenin () were downregulated, while the expression level of fatty acid synthase () and total lipid content were upregulated, leading to premature diapause in adult . These results indicate that is involved in the regulation of reproductive diapause in . - Source: PubMed
Publication date: 2026/05/30
Li LingYao ZhihanWang HaichaoZhang JinghangShan YanminJi YanhuaPang BaopingHan Haibin