Ask about this productRelated genes to: USP44 antibody
- Gene:
- USP44 NIH gene
- Name:
- ubiquitin specific peptidase 44
- Previous symbol:
- -
- Synonyms:
- FLJ14528
- Chromosome:
- 12q21.33
- Locus Type:
- gene with protein product
- Date approved:
- 2003-09-04
- Date modifiied:
- 2015-08-26
Related products to: USP44 antibody
Related articles to: USP44 antibody
- Cisplatin (DDP), as a commonly used chemotherapeutic agent for the clinical treatment of lung adenocarcinoma (LUAD), serves a key function in suppressing tumor progression; however, the development of tumor cell resistance has restricted its clinical application. - Source: PubMed
Publication date: 2026/05/22
Liang ZhiZhang HuiJiang JinhuaLi ChuanchuanYuan Feng - Ubiquitin-specific peptidase 44 (USP44), a deubiquitinating enzyme involved in chromosomal stability and cell cycle control, has been proposed as a potential biomarker and a therapeutic target in various cancers. However, its expression and epigenetic regulation in breast cancer remain understudied. This study investigated USP44 expression and DNA methylation status in breast cancer cell lines, breast cancer tissues and circulating tumor DNA (ctDNA), and their association with clinicopathological features. - Source: PubMed
Publication date: 2026/04/28
Park Kee TaeLee Na-RangJeong Young Ju - Ubiquitination is a critical protein modification process that plays a pivotal role in maintaining cellular homeostasis and is implicated in various pathophysiological processes, including thyroid cancer (THCA). Understanding the roles of ubiquitination-related genes in THCA progression and their interactions with the tumor microenvironment (TME) could provide valuable insights into prognosis and treatment strategies. - Source: PubMed
Publication date: 2026/01/16
Li YilinZeng JutaoGong XiongmeiyuLi WeiLiu JueliLi DanZhong YangyanDeng JunjieDeng JianFeng HaigangLuo JieCao Hong - Chronic obstructive pulmonary disease (COPD) is characterized by a persistent, progressive, and irreversible decline in lung function, primarily driven by persistent airway obstruction and pulmonary inflammation. Cigarette smoking is a major risk factor, as tobacco smoke harms pulmonary epithelial cells, frequently inducing chronic inflammation and ultimately resulting in structural lung lesions. Although pyroptosis is a well-recognized mechanism implicated in cigarette smoke extract (CSE)-induced lung epithelial damage, the specific regulatory roles of early growth response 1 (EGR1) and ubiquitin-specific peptidase 44 (USP44) in this process remain to be fully elucidated. Since inhibiting pyroptosis represents a promising therapeutic strategy for COPD, clarification of the roles of these factors is critically important. - Source: PubMed
Publication date: 2025/11/27
Cao ChaofanZhong ZhaoshuangWu BoZou BoJia HuiXu JiahuanXiao GuixianXia Shuyue - Radiation-induced damage to reproductive tissues presents a major clinical concern with potentially lasting functional consequences. - Source: PubMed
Publication date: 2025/11/26
Zhu LingfengZhang JianpingLiang YaoyaoCheng YuanhangLin NaDeng WenyiLin LinglingChen Jin