Ask about this productRelated genes to: TNFSF14 antibody
- Gene:
- TNFSF14 NIH gene
- Name:
- TNF superfamily member 14
- Previous symbol:
- -
- Synonyms:
- LIGHT, LTg, HVEM-L, CD258
- Chromosome:
- 19p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1998-12-04
- Date modifiied:
- 2017-03-02
Related products to: TNFSF14 antibody
Related articles to: TNFSF14 antibody
- We aimed to characterize associations between plasma proteins and indices of left ventricular (LV) diastolic function in two population-based studies. Eighty-six cardiovascular-related plasma proteins measured by proximity extension assay (PEA) and echocardiography were assessed in the population-based studies PIVUS (n = 1,016; all aged 70) and POEM (n = 502; all aged 50). PIVUS served as the discovery cohort, and the Benjamini-Hochberg procedure was applied to control the false-discovery rate (FDR) < 0.05. POEM was used as the replication cohort. The protein panel was related to diastolic echocardiographic parameters. A larger protein panel of 1,322 proteins was examined only in POEM. Seven of 86 proteins showed replicated associations to the E/A ratio: CD40 ligand (CD40LG), proto-oncogene tyrosine-protein kinase Src (SRC), heat shock protein beta-1 (HSPB1), epidermal growth factor (EGF), TNF superfamily member 14 (TNFSF14), vascular endothelial growth factor D (VEGFD), and endothelial cell-specific molecule 1 (ESM1). Using the larger protein panel in POEM, 81 proteins showed significant associations with the E/A ratio, and five showed significant associations with LA diameter. Pathways linked to LV diastolic filling pattern were signal transduction, metabolic, disease and immune system pathways, enhancing the understanding of LV diastolic function and offering potential for future drug development. - Source: PubMed
Publication date: 2026/09/02
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Amreen BushraMilazzo FlorianaGigase FrederiekeD'souza DarwinSamper NatalieMartin Joseph ThomasKim-Schulze SeungheeLieb Whitneyde Witte Lot DBergink VeerleChen JiaLesseur CorinaRommel Anna-Sophie - Subclinical inflammation linked to monosodium urate (MSU) crystals in gout and asymptomatic hyperuricemia (AH) remains poorly understood. We aimed to assess the cellular and inflammatory proteomic profiles in synovial fluid (SF) associated with MSU crystals, as observed by ultrasound or microscopy. - Source: PubMed
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Andrés MarianoPeral-Garrido María-LuisaOrtuño-Miquel SamantaCaño RocíoGómez-Sabater SilviaBermúdez-García AlejandraLozano TeresaPerdiguero MiguelCaro-Martínez ElenaSánchez-Ortiga RuthRuiz-García CarolinaFrancés Rubén - Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease with variable outcomes after functional endoscopic sinus surgery (FESS). Predictive biomarkers for post-FESS CRSwNP recurrence remain poorly defined. - Source: PubMed
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Dharia TiffanyZawacki MabelMaurer RieBergmark Regan WLee Stella EMaxfield Alice ZRoditi Rachel ELee Pui YHsu EvanLeSon CourtneyKratchmarov RadomirBalestrieri BarbaraLaidlaw Tanya MBuchheit Kathleen M - Clinical decision-making for patients with community-acquired pneumonia (CAP) at risk of organ dysfunction and death is currently guided by clinical evaluation and scores. Every fifth patient with CAP requires admission to the ICU, with a subsequent high mortality; delayed admission to the ICU increases this risk. - Source: PubMed
Publication date: 2026/03/10
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