Ask about this productRelated genes to: SCG5 antibody
- Gene:
- SCG5 NIH gene
- Name:
- secretogranin V
- Previous symbol:
- SGNE1
- Synonyms:
- 7B2, SgV
- Chromosome:
- 15q13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1989-09-22
- Date modifiied:
- 2016-10-05
Related products to: SCG5 antibody
Related articles to: SCG5 antibody
- Physical activity is an established protective factor for colorectal cancer (CRC), but it is unclear if genetic variants modify this effect. To investigate this possibility, we conducted a genome-wide gene-physical activity interaction analysis. - Source: PubMed
Publication date: 2026/02/05
Peoples Anita RObón-Santacana MireiaKim Andre EKawaguchi Eric SFu YuboQu ConghuiMoratalla-Navarro FerranMorrison JohnLin YiArndt VolkerBerndt Sonja IBien Stephanie ABishop D TimothyBouras EmmanouilBrenner HermannBuchanan Daniel DCampbell Peter TChan Andrew TChang-Claude JennyConti David VCorley Douglas AcDevall Matthew ADimou NikiDrew David AGruber Stephen BGunter Marc JHarlid SophiaHarrison Tabitha AHoffmeister MichaelHsu LiHuyghe Jeroen RKeku Temitope OKundaje AnshulLewinger Juan PabloLi LiLynch Brigid MLe Marchand LoicMartín VicenteMurphy NeilNewton Christina COgino ShujiHardikar SheetalOse JenniferPai Rish KPalmer Julie RPapadimitriou NikosPardamean BensPellatt Andrew JPinchev MilaPlatz Elizabeth APotter John DRennert GadRuiz-Narvaez Edward ASakoda Lori CSchoen Robert EShcherbina AnnaStern Mariana CSu Yu-RuThomas Claire ETian YuTsilidis Konstantinos KUm Caroline Yvan Duijnhoven Franzel J BVan Guelpen BethanyVisvanathan KalaWang JunWhite EmilyWolk AlicjaWoods Michael OWu Anna HUlrich Cornelia MPeters UlrikeGauderman W JamesMoreno Victor - Glioblastoma (GBM), as a high-grade glioma, has high invasiveness and poor clinical prognosis. Manganese is an important trace element, has been proven to be closely related to tumor treatment and tumor immunity. It is necessary to explore the correlation between manganese metabolism-related genes and GBM. - Source: PubMed
Publication date: 2026/01/31
Man YiChen WanyueShen GuoanZhao XuanjieLu JunlinZhang Xuxin - The granin gene family of neuropeptides functions as peptide neurotransmitters in the brain for the regulation of neural functions that regulate behaviors. Granins are involved in regulating cognition, memory, depression, aggression, stress, energy expenditure, inflammation, and related. Development of the human brain involves formation of synapses and their spectrum of neurotransmitters to establish neural connections that are required for brain functions. Therefore, the goal of this study was to analyze the gene expression profiles of the granin neurotransmitter genes during human brain development at prenatal, infancy, childhood, adolescence, and adult stages. Granin gene expression in brain development was assessed by quantitative RNA sequencing data from the Allen Human Brain Atlas resource. (neurosecretory protein VGF) expression was significantly increased during development during the prenatal to childhood through adult stages in the anterior cingulate cortex, dorsolateral prefrontal cortex, inferolateral temporal cortex, orbital frontal cortex, posteroventral parietal cortex, primary somatosensory cortex, and primary visual cortex regions. (secretogranin 2) expression was also significantly increased from prenatal to infancy through adult stages in anterior cingulate cortex, dorsolateral prefrontal cortex, inferolateral temporal cortex, orbital frontal cortex, posterior superior temporal cortex, posteroventral parietal cortex, primary somatosensory cortex, and primary visual cortex. A modest number of brain regions showed increased , , and expression in the postnatal periods compared to the prenatal periods. Further, the genes displayed minimal changes throughout development. Overall, these results demonstrate developmental upregulation of and genes, with lesser upregulation of , , and genes, and almost no changes in , , and genes during development. These findings illustrate the differential regulation of granin genes during human brain development. - Source: PubMed
Publication date: 2025/12/02
Demsey Laura LPodvin SoniaHook Vivian - Clean water scarcity represents a significant global challenge, driven by the degradation of surface water resources due to pollution and the impacts of climate change. Atmospheric water harvesting strategies using sorbents offer an available and sustainable solution. Most atmospheric water harvesting studies have focused on hydrogel designs utilizing conventional polymer desiccants derived from fossil fuels. These synthetic polymers are unsustainable and nonbiodegradable, causing negative ecological and public health impacts during degradation, which raises concerns about the direction of eco-friendly material science and technology. Here, biohydrogels (SCG0, SCG3, SCG5, and SCG7) based on chitosan and carboxymethyl cellulose from biomass were synthesized through a simple process. The effect of the cross-linking content on the properties of hydrogels and their water sorption performance were studied through FTIR, TGA, and FESEM analyses, mechanical strength, and water sorption experiments. A SCG5 hydrogel containing 5% w/w glutaraldehyde exhibits the most effective cross-linking formation, leading to superior thermal stability, good compressive strength, and a better water absorption performance compared to the SCG0, SCG3, and SCG7 hydrogels. The SCG5 hydrogel showed strong hydrophilicity when a drop wetted in its surface within 0.26 s. The mass change of SCG5 in water gained 2158% with a maximum sorption rate of 84.7 g g h, and the water vapor sorption capacity of SCG5 at 90% RH reached 28.03% with a maximum sorption rate of 0.55 g g h. Additionally, it exhibited rapid vapor desorption with a rate of 0.39 g g h, releasing over 98% of the absorbed water within 20 min, and remarkable stability after multiple sorption-desorption cycles. Studies on different sorption kinetic models of biohydrogels based on chitosan and carboxymethyl cellulose were carried out, and the experimental data best fitted the Elovich model the most. It means that activated site sorption is the rate-limiting process; the sorption mechanism occurs on a nonuniform surface of biohydrogels or nonconstant active sites. - Source: PubMed
Publication date: 2025/12/08
Nguyen Ngoc ThuyPhan Phat TanTruong Van DanhLe Thanh XuanHoang DongQuy - Physical activity (PA) is an established protective factor for colorectal cancer (CRC), but it is unclear if genetic variants modify this effect. To investigate this possibility, we conducted a genome-wide gene-PA interaction analysis. - Source: PubMed
Publication date: 2025/09/02
Peoples Anita RObón-Santacana MireiaKim Andre EKawaguchi Eric SFu YuboQu ConghuiMoratalla-Navarro FerranMorrison JohnLin YiArndt VolkerBerndt Sonja IBien Stephanie ABishop D TimothyBouras EmmanouilBrenner HermannBuchanan Daniel DCampbell Peter TChan Andrew TChang-Claude JennyConti David VCorley Douglas AcDevall Matthew ADimou NikiDrew David AGruber Stephen BGunter Marc JHarlid SophiaHarrison Tabitha AHoffmeister MichaelHsu LiHuyghe Jeroen RKeku Temitope OKundaje AnshulLewinger Juan PabloLi LiLynch Brigid MMarchand Loic LeMartín VicenteMurphy NeilNewton Christina COgino ShujiHardikar SheetalOse JenniferPai Rish KPalmer Julie RPapadimitriou NikosPardamean BensPellatt Andrew JPinchev MilaPlatz Elizabeth APotter John DRennert GadRuiz-Narvaez Edward ASakoda Lori CSchoen Robert EShcherbina AnnaStern Mariana CSu Yu-RuThomas Claire ETian YuTsilidis Konstantinos KUm Caroline Yvan Duijnhoven Franzel J Bvan Guelpen BethanyVisvanathan KalaWang JunWhite EmilyWolk AlicjaWoods Michael OWu Anna HUlrich Cornelia MPeters UlrikeGauderman W JamesMoreno Victor