Ask about this productRelated genes to: PTPRCAP antibody
- Gene:
- PTPRCAP NIH gene
- Name:
- protein tyrosine phosphatase receptor type C associated protein
- Previous symbol:
- -
- Synonyms:
- LPAP, CD45-AP
- Chromosome:
- 11q13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1996-04-22
- Date modifiied:
- 2019-02-14
Related products to: PTPRCAP antibody
Related articles to: PTPRCAP antibody
- Hepatitis B virus (HBV) infections are associated with an increased risk of B-cell lymphomas, including follicular lymphoma (FL). Chronic HBV infection and shifts in infection status following treatment can influence lymphomagenesis and immune reprogramming, potentially affecting clinical outcomes. Using the CosMx Spatial Molecular Imaging, after integrated with dynamic HBV infection states and duration of overt infection, this refines four recurrent patterns, especially memory B cell-like malignant cells (MBLM) subtype (PTPRCAP + ) that is traced with atypical features and latent indolence, and virus protein transport-related follicular dendritic cell (FDC) which shows interplay with MBLM. Except for virus-induced immune exhaustion, distinct contributions to POD24 occurrence from malignant cells and immunosuppressive cell communities under distinct HBV infection states are discerned such as through CCL21/CCR7 signaling pathway. Taken together, our spatial multicellular dynamics reveal an increased prevalence of MBLM and variable FDC phenotypes which is associated with POD24 occurrence in HBV-related FL tumors. - Source: PubMed
Publication date: 2026/03/09
Deng YuweiZhang QingyuanJia ZhenyuanThorne Rick FZhang HuilaiLiu XuhuiMa Jianli - PTPRCAP (protein tyrosine phosphatase receptor C-associated protein) has been implicated in tumor suppression in several malignancies; however, its role in lung adenocarcinoma (LUAD) remains unclear. This study aimed to investigate the expression profile and functional significance of PTPRCAP in LUAD. - Source: PubMed
Publication date: 2025/12/18
Yang YutingZhao BaoshanJiang YingjieHan XiaoliHuang JingtaoSun GuangruiLiang Zongying - Almost all mammals rely on the thymus and bone marrow to generate and differentiate B and T cells essential for adaptive immunity. A few members of the family Soricidae, or true shrews within Eulipotyphla, have also evolved an enlarged pancreas of Aselli, a kidney-sized organ hypothesized to serve this primary immune role, and whose gene expression profile is unknown. - Source: PubMed
Publication date: 2025/10/21
Thomas William RBaldoni CeciliaLama Tanya MZeng YuanyuanCorthals Angelique Pvon Elverfeldt DominikNieland JohnDechmann Dina K NDávalos Liliana M - To investigate the regulatory mechanism by which MicroRNA-582-3p (-582-3p) targets protein tyrosine phosphatase receptor type C-associated protein () and modulates Wnt/β-catenin signaling in lung adenocarcinoma pathogenesis. - Source: PubMed
Publication date: 2025/09/23
Yang YutingZhao SongHan XiaoliGuo PengfeiZhao BaoshanLiang Zongying - Injection drug use (IDU) leads to immune system dysfunction, thereby increasing the risk of opportunistic infection. There is a critical need to reveal the role of IDU in the immunopathogenesis of HIV infection. - Source: PubMed
Publication date: 2024/10/14
Gao Kai-ChengMou TangweiZhao YuLiang DanKuang Yi-QunJia Jie