Ask about this productRelated genes to: PGM2 antibody
- Gene:
- PGM2 NIH gene
- Name:
- phosphoglucomutase 2
- Previous symbol:
- -
- Synonyms:
- FLJ10983
- Chromosome:
- 4p14
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-22
- Date modifiied:
- 2014-11-19
Related products to: PGM2 antibody
Related articles to: PGM2 antibody
- Lung cancer remains a leading cause of cancer incidence and mortality globally. Metabolic reprogramming promotes tumor progression and shapes an immunosuppressive tumor microenvironment. Galactose metabolism is involved in multiple malignancies, but its prognostic value in lung adenocarcinoma (LUAD) remains unclear. This study aimed to develop and internally validate a galactose metabolism-related multigene prognostic model for LUAD. - Source: PubMed
Publication date: 2026/08/27
Zhang FengFu JianCui XuxuGao XutongKang Yanxia - This study aimed to evaluate the profile of salivary proteins in young hookah and conventional cigarette users without apparent oral mucosal lesions, and to correlate the findings with clinical variables related to tobacco use. - Source: PubMed
Publication date: 2026/07/28
Costa Thayná Isabele Stopiellode Souza Salardani Murilodo Carmo Carvalho Bruna FernandesZimiani Caroline FariaSantos Joyce NascimentoDe Rossi TatianeAlmeida Janete DiasHayashi Jackelinne YukaTashima Alexandre KeijiLeme Adriana Franco PaesZelanis AndréAlves Mônica Ghislaine Oliveira - Growth traits, as core economic indicators in pig breeding, are closely associated with production costs, rearing duration, and final carcass quality and have thus consistently been a major focus of genetic improvement. This study aimed to identify candidate genes affecting Age to 120 kg live weight (AGE120), Backfat thickness at 120 kg (BF120), and Loin muscle depth at 120 kg (LMD120) in pigs. Ear tissue samples were collected from 3364 healthy adult pigs (including 558 boars and 2805 sows) from three breeds: Large White, Landrace, and Duroc. Genotyping was performed using an 80 K functional site array, and quality-controlled SNP (Single-Nucleotide Polymorphism) loci were subjected to genotype imputation, resulting in 15,447,611 loci obtained. Genome-wide association studies (GWASs) for Age to 120 kg live weight, Back fat thickness at 120 kg, and Loin muscle depth at 120 kg were conducted using a mixed linear model in Genome-wide Complex Trait Analysis (GCTA). Genes located within 500 kb upstream and downstream of significant GWAS loci were extracted using the biomaRt package in R. Furthermore, colocalization analysis was performed using expression Quantitative Trait Locus (eQTL) data of 34 tissues from the PigGTEx database to identify genes that share the same causal variant as the GWAS signals. Through integrated GWAS and eQTL colocalization analysis, in addition to five previously reported genes associated with pig growth traits (, , , , and ), a set of novel, high-confidence candidate genes was identified: , , , , , , , , and . These findings enrich our understanding of the genetic architecture underlying growth traits in pigs at heavy body weights and provide an important foundation for subsequent functional validation and molecular breeding applications. - Source: PubMed
Publication date: 2026/07/22
Wu XiangziWu JunjingGu YirenQiao MuZhou JiaweiLi ZipengFeng YueChen TongChen DakeMei ShuqiPeng XianwenXu Zhong - As the core treatment for cervical cancer, chemoradiotherapy efficacy is often limited by tumor heterogeneity-driven resistance. During chemoradiotherapy, the tumor microenvironment undergoes dynamic remodeling, with residual malignant cells evolving adaptively. However, the key regulatory genes driving therapeutic resistance remain elusive at single-cell resolution, which hinders the development of novel targeted therapies. - Source: PubMed
Publication date: 2026/06/16
Yang HuaxiangZheng QingLi XinWang Jingzhi - Prostatic hyperplasia is a common condition among aging males characterized by excessive prostate cell proliferation, and while it is a benign process, it involves significant metabolic reprogramming and immune infiltration-features typically associated with malignant tumors. This study aimed to elucidate the interaction network between the PIEZO channels and genes related to glycometabolic reprogramming and mitochondrial oxidative phosphorylation (OXPHOS), highlighting their roles in the progression of prostatic hyperplasia. - Source: PubMed
Publication date: 2026/03/23
Zheng YajieZhao FuguangXu PengweiZeng ChuchuSun ZongrunWu GuanlinWang Yibin