Ask about this productRelated genes to: MRFAP1 antibody
- Gene:
- MRFAP1 NIH gene
- Name:
- Morf4 family associated protein 1
- Previous symbol:
- -
- Synonyms:
- PAM14, PGR1
- Chromosome:
- 4p16.1
- Locus Type:
- gene with protein product
- Date approved:
- 2005-03-07
- Date modifiied:
- 2014-11-19
Related products to: MRFAP1 antibody
Related articles to: MRFAP1 antibody
- The aim of the present work was to find an efficient method for safe and reliable expansion of human dental pulp cells (hDPCs) in vitro. Here, we examined the effect of a novel recombinant E8 fragment of Laminin-511 (iMatrix-511) in hDPCs regarding viability and cell spreading. Further, we investigated the underlying mechanisms governing its effects in hDPCs using RNA sequencing (RNA-seq). - Source: PubMed
Publication date: 2024/06/18
Tang JiaHuang Xiaofeng - Liver cancer incidence among American Indians/Alaska Natives has risen over the past 20 years. Peripheral blood DNA methylation may be associated with liver cancer and could be used as a biomarker for cancer risk. We evaluated the association of blood DNA methylation with risk of liver cancer. - Source: PubMed
Publication date: 2023/11/27
Slowly MoniqueDomingo-Relloso ArceSantella Regina MHaack KarinFallin Daniele MTerry Mary BethRhoades Dorothy AHerreros-Martinez MiguelGarcia-Esquinas EstherCole Shelley ATellez-Plaza MariaNavas-Acien AnaWu Hui-Chen - Using chip array assays, we identified differentially expressed genes via a comparison between luminal A breast cancer subtype and normal mammary ductal cells from healthy donors. In silico analysis confirmed by western blot and immunohistochemistry revealed that C-JUN and C-FOS transcription factors are activated in luminal A patients as potential upstream regulators of these differentially expressed genes. Using a chip-on-chip assay, we identified potential C-JUN and C-FOS targets. Among these genes, the NRIP1 gene was revealed to be targeted by C-JUN and C-FOS. This was confirmed after identification and validation with transfection assays specific binding of C-JUN and C-FOS at consensus binding sites. NRIP1 is not only upregulated in luminal A patients and cell lines but also regulates breast cancer-related genes, including PR, ESR1 and CCND1. These results were confirmed by NRIP1 siRNA knockdown and chip array assays, thus highlighting the putative role of NRIP1 in PGR, ESR1 and CCND1 transcriptional regulation and suggesting that NRIP1 could play an important role in breast cancer ductal cell initiation. - Source: PubMed
Publication date: 2021/10/27
Binato RenataCorrêa StephanyPanis CarolinaFerreira GersonPetrone Igorda Costa Igor RodriguesAbdelhay Eliana - Unpredictability in acquiring an adequate number of high-quality oocytes following ovarian stimulation is one of the major complications in controlled ovarian hyperstimulation (COH). Genetic predispositions of variations could alter the immunological profiles and consequently be implicated in the variability of ovarian response to the stimulation. - Source: PubMed
Publication date: 2021/05/29
Ghaderian Sayyed Mohammad HosseinAkbarzadeh RezaSalehpour Saghar - Black race is associated with worse outcomes in early breast cancer. We evaluated clinicopathologic characteristics, the 21-gene recurrence score (RS), treatment delivered, and clinical outcomes by race and ethnicity among women who participated in the Trial Assigning Individualized Options for Treatment. - Source: PubMed
Albain Kathy SGray Robert JMakower Della FFaghih AmirHayes Daniel FGeyer Charles EDees Elizabeth CGoetz Matthew POlson John ALively TracyBadve Sunil SSaphner Thomas JWagner Lynne IWhelan Timothy JEllis Matthew JWood William CKeane Maccon MGomez Henry LReddy Pavan SGoggins Timothy FMayer Ingrid ABrufsky Adam MToppmeyer Deborah LKaklamani Virginia GBerenberg Jeffrey LAbrams JeffreySledge George WSparano Joseph A