Ask about this productRelated genes to: INHA antibody
- Gene:
- INHA NIH gene
- Name:
- inhibin subunit alpha
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 2q35
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-22
- Date modifiied:
- 2018-04-23
Related products to: INHA antibody
Related articles to: INHA antibody
- Studies on the comprehensive utility of complete blood count-derived inflammatory biomarkers (CBC-IBs) as biomarkers in pembrolizumab-treated advanced non-small-cell lung cancer (NSCLC) are scarce. This study aimed to investigate the clinical relevance of a panel of CBC-IBs as potential predictive biomarkers and assess whether integrating the systemic immune-inflammation index (SII) with programmed death-ligand 1 (PD-L1) expression could overcome the limitations of PD-L1 as a standalone predictive biomarker. Our real-world preliminary study was conducted on a cohort of patients with advanced NSCLC. Patients who had undergone PD-L1 immunohistochemistry testing at the time of diagnosis, and had completed at least three cycles of pembrolizumab were included. The CBC-IBs analyzed in this study were calculated using absolute cell counts of neutrophils, lymphocytes, monocytes, and platelets. A total of 102 patients were included. Low baseline SII was significantly associated with superior progression-free survival (PFS) ( = 0.031) and overall survival (OS) ( = 0.004). In multivariate analysis, SII emerged as the strongest independent predictor for OS among all evaluated CBC-IBs. Furthermore, patients with a combination of low SII and high PD-L1 expression demonstrated the most favorable survival outcomes. Although further prospective and multicenter studies are needed to validate the generalizability of our findings, the clinical implication is that the use of pretreatment SII and/or PD-L1 expression values may predict therapeutic outcomes and assist in optimizing individualized treatment strategies for patients with advanced NSCLC. - Source: PubMed
Publication date: 2026/05/21
Cha HyungkeunLee Yong SeokKwon Gui YoungKim BoranMoon YeonsookKim LuciaNam Hae-Seong - Cone-rod dystrophy (CRD) is an inherited retinal dystrophy characterized by decreased visual acuity, color vision defects, and progressive loss of peripheral vision. RAB28-associated CRD is genetically homogeneous and results from pathogenic variants in the RAB28 gene, which is essential for photoreceptor function. - Source: PubMed
Publication date: 2026/06/03
Park JoonhongJang WooriAhn YoojungLee Haeng-Jin - To confirm the accurate pN0 status in patients with cT1-2N0 esophageal squamous cell carcinoma (ESCC) and recommend an optimal lymph node (LN) count for accurate nodal staging. - Source: PubMed
Publication date: 2026/06/02
Park Seong YongPark BoramYun Jae KwangKim Hyeong RyulKim Yong-HeeJeon Yeong JeongLee JungheeCho Jong HoKim Hong KwanChoi Yong SooZo Jae IlShim Young Mog - - Source: PubMed
Publication date: 2026/06/03
Choi Jun HyuckAhn Jin WooSon Young MunRho Beom YongChung Doo Yong - Previous systematic reviews have adopted binary exposure classifications without characterizing the heterogeneity of welding fume exposures. We aimed to estimate lung cancer risk from welding fumes with systematic exposure characterization by process type, base material, and metal fume component, and to examine evidence for related high-temperature processes. - Source: PubMed
Publication date: 2026/06/01
Kim YangwooKim Eun MiKim Inah