Ask about this productRelated genes to: S100B protein
- Gene:
- S100B NIH gene
- Name:
- S100 calcium binding protein B
- Previous symbol:
- -
- Synonyms:
- S100beta
- Chromosome:
- 21q22.3
- Locus Type:
- gene with protein product
- Date approved:
- 1988-06-27
- Date modifiied:
- 2014-11-18
Related products to: S100B protein
Related articles to: S100B protein
- The glymphatic system, which is most active during sleep, may be disrupted in obstructive sleep apnea (OSA). We evaluated glymphatic function in children with OSA using diffusion tensor imaging-along the perivascular space (DTI-ALPS) index together with serum glial fibrillary acidic protein (GFAP) and S100 calcium-binding protein B (S100B) levels. - Source: PubMed
Publication date: 2026/04/20
Sunman Birceİpek Ömer FarukGümeler EkimAlboğa DidemKarataş MeltemÇapraz Yavuz BurcuTezel Yalçın HülyaŞenkalfa BurcuEmiralioğlu NagehanSabuncuoğlu SunaGönç Elmas NazlıÖzön Zeynep AlevYalçın EbruDoğru DenizOğuz Kader KÖzçelik Uğur - Autoimmune glial fibrillary acidic protein astrocytopathy (A-GFAP-A) is a recently defined immune-mediated disorder of the central nervous system (CNS). At present, diagnosis relies primarily on the detection of GFAP-IgG in cerebrospinal fluid (CSF); however, the limited specificity of this biomarker restricts its clinical utility. This study aimed to investigate the expression profiles and clinical relevance of additional protein biomarkers in A-GFAP-A. - Source: PubMed
Publication date: 2026/04/08
Liu LuMa BoyaPeng JiahuiLi NingZhang YinghuiLiu QiangYang JuanZhao LiLi YiWang YanbaiYang Xiao - Postoperative delirium causes significant morbidity and mortality. Delirium is associated with the presence of plasma and CSF biomarkers, including interleukin-6 (IL-6). When IL-6 binds to the non-membrane-bound soluble IL-6 receptor (sIL-6R), the resultant binary complex, IL-6·sIL-6R, triggers pro-inflammatory processes called trans-signalling. While murine models implicate central IL-6 trans-signalling in perioperative cognitive dysfunction, there are few clinical reports addressing its role in delirium. The primary aim was to investigate whether postoperative changes in CSF IL-6, sIL-6R and IL-6·sIL-6R complexes were associated with the incidence and severity of postoperative delirium. We also explored whether CSF sIL-6R was related to peripheral inflammation and blood-brain barrier permeability. - Source: PubMed
Publication date: 2026/04/10
Wu Justin GTaylor JenniferKunkel DavidMaze MervynPearce Robert ASanders Robert DLennertz Richard - Postoperative cognitive dysfunction (POCD) is defined as a persistent decline in cognitive performance after a surgical procedure, for which no cause can be identified. S100B is a calcium-binding protein present in many organs, including the brain. Serum levels have been suggested to be related to POCD. The purpose of this systematic review and meta-analysis is to assess the association between S100B serum levels and cognitive dysfunction after non-cardiac surgeries. - Source: PubMed
Publication date: 2026/04/16
Asefi SabaOmidi PouyaJazi KimiaFateh AzadehZanjanbar Dorsa BahramiSadeghi SiminHajiesmaeili Mohammadreza - Adverse event in the perinatal period constitutes today the wider bulk of investigation. Perinatal asphyxia (PA) and prematurity are the common causes of injury of high risk pregnancies (HR) and can lead to perinatal death or cognitive and neuro-motor impairment in later life. Despite the use of clinical, laboratory, ultrasound and radiological monitoring procedures, for the estimation of the severity of pre-perinatal brain injury and prognosis, there is still a demand for an early and objective diagnostic and prognostic parameter. Former research suggests that several neurobiomarkers could serve as potential both diagnostic and prognostic tools in HR and newborns. Among them, S100B is a well-known biomarker that could be assessed in different biological fluids such as maternal blood. The inclusion in clinical daily practice of a biomarker, measurable in the maternal blood, able to detect at earliest stage fetal/neonatal neurological damage is of utmost importance. Therefore, in the present review we offer an update of the potential usefulness of the measurement in the maternal blood of a well-established marker of perinatal brain development/damage namely S100B. - Source: PubMed
Publication date: 2026/04/15
Abella LauraLevantini GabriellaStrozzi ChiaraMaconi AntonioBellinaso MariangelaDi Clemente Katiade Laurenzi VincenzoGazzolo FrancescaD'Adamo EbeGazzolo Diego