Ask about this productRelated genes to: VASP antibody
- Gene:
- VASP NIH gene
- Name:
- vasodilator stimulated phosphoprotein
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 19q13.32
- Locus Type:
- gene with protein product
- Date approved:
- 1996-06-07
- Date modifiied:
- 2017-06-13
Related products to: VASP antibody
Related articles to: VASP antibody
- Electron-spin-based investigations using density functional theory (DFT) methods, which play a significant role in the development of catalytic approaches, are lacking in the literature. Meanwhile, advances in photo- and electro-driven catalytic processes rely not only on industrial-scale development and experimental validation, but also on rigorous, fundamental investigations based on DFT to pinpoint the origins of key challenges and how to overcome them. This review provides a comprehensive overview of recent progress in spin-resolved DFT and its application to the investigation of (photo)electrocatalytic mechanisms and materials. Therefore, in this article, we discuss electron-spin-based concepts, including spin polarization and its role in catalytic applications, the application of strain, the introduction of external electric fields, and the integration of multiple control techniques. Additionally, we review advanced exchange-correlation approaches, including GGA, LDA+, and hybrid functionals such as HSE, which improve the accuracy of band gap calculations and enable a more reliable description of spin polarization, magnetic ordering, and spin-dependent electronic structures. Commonly used DFT software for studying electrochemical and photocatalytic materials is also presented to guide both computational and experimental researchers. Among these tools, VASP and CASTEP are the most frequently employed. Regarding computational methods, the GGA framework-especially the PBE functional and the hybrid GGA-HSE approach-is widely applied, whereas studies using LDA or LDA+ are relatively limited in this field. Particularly in the approximation, the DFT exchange-correlation potential is replaced by a nonlocal, energy-dependent self-energy, which not only corrects band-gaps but also modifies spin polarization, magnetic ordering, band dispersions and effective masses, affecting the charge carrier mobility and recombination, key factors for photocatalytic efficiency. By critically assessing the current progress, this review intends to highlight promising avenues for future research in harnessing electron spin control to unlock new potential in photocatalytic applications. - Source: PubMed
Publication date: 2026/08/27
Mohammadi SaeedehShahrokhi MasoudKaya ŞükrüDoustkhah Esmail - : Platelets are anucleate cells that play a crucial role in primary hemostasis and arterial thrombosis, contributing to cardiovascular diseases. Eugenol, a bioactive phenolic compound, exhibits vasodilatory, antibacterial, and anticancer properties and inhibits platelet aggregation induced by collagen and arachidonic acid (AA). AA is a critical lipid component of the platelet membrane and a precursor for potent signaling molecules that mediate platelet activation. However, the precise mechanisms through which eugenol modulates AA-stimulated platelet activation remain unclear. : Human platelets were pretreated with eugenol and subsequently stimulated with AA. Platelet aggregation, ATP release, intracellular calcium mobilization, and P-selectin expression were measured. JNK, p38 MAPK, ERK, and vasodilator-stimulated phosphoprotein (VASP) phosphorylation were analyzed by Western blotting. SP600125, SQ22536, and ODQ were used to examine the involvement of JNK and cyclic nucleotide signaling pathways. Antithrombotic effects were further evaluated in a mouse mesenteric thrombosis model. : Eugenol significantly suppressed AA-induced platelet aggregation, ATP release, calcium mobilization, and P-selectin expression, selectively reducing JNK phosphorylation without affecting p38 MAPK or ERK. SP600125 produced similar inhibitory effects. Neither SQ22536 nor ODQ reversed eugenol's inhibitory effects on platelet aggregation. Furthermore, eugenol did not alter VASP phosphorylation at Ser157 or Ser239. In vivo, real-time intravital imaging showed that eugenol and SP600125 delayed thrombus formation and prolonged occlusion time. : These findings suggest that eugenol exerts inhibitory effects that may involve modulation of JNK phosphorylation, independent of cyclic nucleotide/VASP pathways in AA-induced platelet activation, highlighting its potential as an antithrombotic agent. - Source: PubMed
Publication date: 2026/08/11
Hsu Chia-YuanHuang Wei-ChiehSheu Joen-RongDarmanto Arief GunawanHsieh Cheng-YingHsia Chih-Wei - Large language models (LLMs) and agents have lately propelled advances in artificial intelligence for science (AI4S). In this work, we propose a toolset-first paradigm for intelligent computation that decouples the tools from the agents via the model context protocol (MCP). We construct four MCP servers, HEA-MCP, VASP-MCP, LAMMPS-MCP, and OpenClaw-MCP. HEA-MCP provides theoretical calculations for high-entropy alloys (HEA). VASP-MCP and LAMMPS-MCP provide first-principles calculations and molecular dynamics simulations, respectively. OpenClaw-MCP contains an autonomous agent, OpenClaw, which renders the autonomous agent a callable tool. OpenClaw itself also supports the MCP to form a recursive agent architecture. By packaging the tools as MCP servers and connecting them to a general MCP-compatible agent, domain-specific capabilities can be obtained without building dedicated agents and can be reused across agentic frameworks. - Source: PubMed
Zhao JinLi HaichaoHe TaoLiu ChangXu LinaHe XiaoFang Guoyong - We assess the dynamical properties of liquid water predicted by several density functionals using machine-learning interatomic potentials. MACE models were trained for SCAN, RPBE-D3/zd, revPBE-D3/zd, revPBE0-D3/BJ, PBE0-D3/zd, and PBE0-D3/BJ using previously reported ab initio datasets. We compare translational, rotational, and viscous dynamics through time-correlation functions, which resolve relaxation processes across different timescales, and through the corresponding long-time kinetic coefficients. The diffusion coefficient, second-rank orientational relaxation time, and shear viscosity reveal systematic differences among functionals. Part of these differences can be rationalized as shifts along the phase diagram, as comparisons relative to the melting temperature of each functional reduce the spread in the dynamical observables. Among the functionals considered, RPBE-D3/zd provides the best overall agreement with experiment. We, therefore, perform a broader validation of RPBE-D3/zd using a Behler-Parrinello neural-network potential over a wide range of temperatures, densities, and pressures. The model reproduces the magnitude and anomalous pressure dependence of the diffusion coefficient, gives generally good viscosities, and captures the temperature dependence of the rotational relaxation time. - Source: PubMed
Montero de Hijes PNeubeck LKresse GDellago C - Rotational atherectomy (RA) and orbital atherectomy (OA) are widely used for plaque modification in severely calcified coronary lesions. Historical concerns have suggested that high rotational speeds may induce platelet activation during percutaneous coronary intervention (PCI), but data in the context of contemporary procedural strategies and dual antiplatelet therapy (DAPT) remain limited. - Source: PubMed
Publication date: 2026/08/13
Roussel TCuisset TBoyer JBressollette ESeguy BHonton BAmabile NDeharo P