Ask about this productRelated genes to: CD95 antibody
- Gene:
- FAS NIH gene
- Name:
- Fas cell surface death receptor
- Previous symbol:
- FAS1, APT1, TNFRSF6
- Synonyms:
- CD95, APO-1
- Chromosome:
- 10q23.31
- Locus Type:
- gene with protein product
- Date approved:
- 1992-06-25
- Date modifiied:
- 2019-04-23
Related products to: CD95 antibody
Related articles to: CD95 antibody
- Metastasis is the leading cause of death in clear cell renal cell carcinoma (ccRCC) patients. Anoikis, a form of programmed cell death induced by the loss of cell-extracellular matrix interactions, is a critical factor in hindering metastasis. Nevertheless, the regulatory mechanisms underlying anoikis resistance in ccRCC remain poorly characterized and warrant further investigation. - Source: PubMed
Publication date: 2026/05/01
Wei HaotianLi ShenglongZhu ShimiaoXu ChenglongWang YueLi ZhaochenGuan YujingLi JiahangJiang RunzeGe XianglianYi TailongXu XingXie YangTian JingPiao YingzheZhang PingQuan ChangyiJin Xun - Low omega-3 Fatty acids (FAs) levels are associated with insulin resistance and upregulation of adiponectin and women with Gestational diabetes mellitus (GDM) have lower n-3 FAs. The current study assesses the association between FAs intake and individual fatty acid levels and ratios in maternal and cord erythrocyte FAs' profile GDM among sample of pregnant Arabic-speaking women in Oman. - Source: PubMed
Publication date: 2026/05/01
Al Sinani MohammedJohnson MarkCrawford MichaelAl Maqbali Mohammed - Degenerative cervical myelopathy (DCM) is the most common cause of cervical spinal cord impairment in adults. It is described as progressive, age-related spinal cord compression due to degenerative changes in the spinal column. While the mechanical pathology of DCM is well characterized, the immune system's role in the disease's neurological progression and potential as a therapeutic target remains unclear. The authors aimed to comprehensively review the available literature on immunological involvement in DCM pathogenesis. Understanding the interactions between inflammation, apoptosis, and neurodegeneration in DCM may provide insights into novel treatment strategies. - Source: PubMed
Publication date: 2026/05/01
Chabot Peter JWinans Nathan JFuller Joshua SDadario Nicholas BCreveCoeur Travis SRolfe NathanielHowell Harrison JSampath Shailen GChou DeanChan Andrew K - The transition from gestation to lactation is a critical period that leads to insulin resistance (IR) in dairy cows. IR detection requires invasive sampling and laborious methods; therefore, novel and non-invasive approaches are essential. Extracellular vesicles (EVs) are nano-sized particles released by cells and are linked to disease pathophysiology. Hence, the present study aimed to explore the potential application of cow milk EVs (MEVs) in detecting IR in dairy cows. An intravenous glucose tolerance test (IVGTT) was performed ( = 12), and the cows were classified as low, moderate, or high IR based on prepartum area under the curve insulin values. MEVs were enriched using double-size exclusion chromatography and physico-chemically characterized. The results revealed that the particle diameter of MEVs was significantly higher ( ≤ 0.05) in the high-IR group compared to other groups. Out of 26 fatty acids (FAs) detected in MEVs, three long-chain FAs differed significantly in abundance ( ≤ 0.05) in high-IR group. Proteomic analysis revealed a correlation of inflammation and the IR-related proteins; Annexin A1 and Rab proteins, to IR severity. Overall, this study identified promising predictors of IR in cows, supporting the development of non-invasive biomarkers for early detection, facilitating improved herd and disease management, and reducing economic losses. - Source: PubMed
Publication date: 2026/05/01
Prasadani MadhushaJaakson HannoKaris PriitMuhandiram SubhashiniHenno MerikeKuusik SirjeLing KatriRajapaksha HarindaOts MeelisAndronowska AnetaPradeep Kodithuwakku SurangaVolke ValloFazeli Alireza - Belapectin reduced variceal development in a subgroup of patients with MASH cirrhosis. We report the efficacy and safety of belapectin in patients with MASH cirrhosis and portal hypertension without varices at baseline. - Source: PubMed
Publication date: 2026/05/01
Chalasani NagaVuppalanchi RajNoureddin MazenShiffman Mitchell LLawitz EricMena EdwardGunn Nadege TLadron de Guevara LauraElgouhari HeshamSafadi RifaatJamil KhurramHarrison Stephen AAlkhouri Naim