Ask about this productRelated genes to: THOP1 antibody
- Gene:
- THOP1 NIH gene
- Name:
- thimet oligopeptidase 1
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 19p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1995-07-06
- Date modifiied:
- 2015-09-08
Related products to: THOP1 antibody
Related articles to: THOP1 antibody
- Using proximity extension proteomic arrays (PEA), we previously identified a nine-biomarker CSF protein panel reflecting different biological processes dysregulated in Alzheimer´s disease (AD) that discriminated AD from non-AD dementias (i.e., dementia with Lewy bodies (DLB) and Frontotemporal dementia (FTD)). We translated this AD-Differential diagnostic panel into immunoassays for large-scale analysis and validated its discriminative performance in an independent cohort. - Source: PubMed
Publication date: 2026/02/11
Hok-A-Hin Yanaika SBongers BramBolsewig KatharinaBoonkamp LynnRuiters Daimy NLemstra Afina Wvan der Flier Wiesje MPijnenburg Yolande A LDel Campo MartaTeunissen Charlotte E - Recent evidence suggests that external stimuli can shape transcriptomes, a field emerging as sensogenomics. Specifically, the analysis of capillary blood samples has shown that musical stimuli can modulate gene expression patterns, not only in healthy individuals but also in those with age-related cognitive disorders (ACD). - Source: PubMed
Publication date: 2025/09/23
Gómez-Carballa AlbertoNavarro LauraMallah Nour El ZahraaBello XabierPischedda SaraViz-Lasheras SandraCurrás María JoséFerreirós-Vidal IsabelMallah NarmeenMontoto-Louzao JuliánCamino-Mera AlbaCastelo-Martínez LúaRey-Vázquez SaraRedondo LorenzoDacosta-Urbieta AnaRivero-Calle IreneRodríguez-Tenreiro CarmenMartinón-Torres FedericoSalas Antonio - In a systematic explorative study of genetic patterns on chromosome 19, we discovered a pattern comprising 23 SNP alleles that is significantly associated with late-onset Alzheimer's disease (AD). This association was validated using two independent datasets. The pattern includes (), which has a long and disputatious relationship with AD. It also spans () and () and is upstream from (). We utilized population data to observe the frequencies of this genetic pattern for 11 different ancestries and noted that it is highly common for Europeans and relatively infrequent for Africans. This research provides a distinct genetic signature for AD risk, as well as insights into the complicated relationship between this disease and . - Source: PubMed
Publication date: 2025/02/26
Climer Sharlee - Traumatic brain injury (TBI) can generally be divided into focal damage and diffuse damage, and neonate Hypoxia-Ischemia Brain Damage (nHIBD) is one of the causes of diffuse damage. Patients with nHIBD are at an increased risk of developing Alzheimer's disease (AD). However, the shared pathogenesis of patients affected with both neurological disorders has not been fully elucidated. - Source: PubMed
Publication date: 2025/01/13
Zhang ShengjieZhang RuqiuChen ZhaoqinShao ZihanLi AnLi FanHuang Fang - Among multi-ethnic Asians, type 2 diabetes (T2D) clustered in three subtypes; mild obesity-related diabetes (MOD), mild age-related diabetes with insulin insufficiency (MARD-II) and severe insulin-resistant diabetes with relative insulin insufficiency (SIRD-RII) had differential cardio-renal complication risk. We assessed the proteomic profiles to identify subtype specific biomarkers and its association with diabetes complications. - Source: PubMed
Publication date: 2024/07/25
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