Ask about this productRelated genes to: ERAS antibody
- Gene:
- ERAS NIH gene
- Name:
- ES cell expressed Ras
- Previous symbol:
- HRAS2, HRASP
- Synonyms:
- -
- Chromosome:
- Xp11.23
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-22
- Date modifiied:
- 2015-08-25
Related products to: ERAS antibody
Related articles to: ERAS antibody
- Highly sensitized kidney transplant candidates face major barriers to transplantation because broad anti-HLA antibody reactivity substantially limits donor compatibility. We conducted a retrospective cohort study comparing two allocation eras in Pernambuco, Brazil: a pre-EpViX era (2005-2014; n=3,136) and an EpViX era (2016-2025; n=4,544). We evaluated the association between an epitope-informed definition of unacceptable antigens integrated with virtual crossmatching and access to deceased-donor kidney transplantation. The proportion of candidates who underwent transplantation was higher during the EpViX era (50%) than during the pre-EpViX era (36%) (p<0.001), while median waiting time among transplanted recipients decreased from 22 to 7 months (p<0.001). Among highly sensitized candidates (cPRA ≥80%), the estimated probability of transplantation at 12 months was 17% in the EpViX era compared with 3% in the pre-EpViX era. In adjusted analyses, listing during the EpViX era was associated with a higher likelihood of transplantation (HR 2.55; 95% CI 2.37-2.74; p<0.001). Epitope-level virtual crossmatch demonstrated high concordance with prospective complement-dependent cytotoxicity crossmatch, with sensitivity of 98.7%, specificity of 93.4%, and a negative predictive value of 99.6%. An allocation strategy incorporating an epitope-informed definition of unacceptable antigens was associated with greater access to deceased-donor kidney transplantation, including among highly sensitized candidates, while maintaining high concordance with prospective crossmatch testing. - Source: PubMed
Publication date: 2026/07/28
Brandão Rafael Melo Santos de Serpada Silva Adalberto Socorrode Andrade Luís Gustavo ModelliSousa Luiz Claudio Demes da Matade Andrade João Marcelo MedeirosCavalcanti Frederico Castelo BrancoWillcox Glauco HenriqueCavalcante Samuel de AlencarCavalcanti Neto Ruy de Limade Andrade Amaro MedeirosPinto Alexandre de Holanda CavalcantiCabral Diogo Buarque CordeiroDos Santos Tatiana Cristina Manzi SenaLeão Isa Maria TeixeiraGuimarães Elizabeth LimaCorrea Bruno de Melodo Rego André Bezerra Pereirado Monte Semiramis Jamil Hadad - Delayed graft function (DGF) is a frequent early complication after kidney transplantation. We systematically reviewed artificial intelligence and machine learning (AI/ML) models that use routine clinical variables to predict DGF. - Source: PubMed
Publication date: 2026/08/20
Yadav SagarYadav AakashBais Shubham SinghKhurana UditSharma AartiJha Prasoon - Hypophysitis in sarcoidosis is a rare manifestation of neurosarcoidosis that may cause permanent endocrine dysfunction, visual impairment, and neurological morbidity. We performed a systematic review to characterize its clinical presentation, diagnostic findings, treatment, and outcomes. - Source: PubMed
Publication date: 2026/08/20
Cavalcanti Julia F Bde Souza Sara CaixetaLucato Leandro TavaresGlezer AndreaSilva Guilherme Diogo - A cornerstone of enhanced recovery after surgery (ERAS) pathways is preemptive analgesia-the administration of analgesic medications prior to incision to blunt central sensitization and postoperative pain. We now evaluate the efficacy of different preoperative analgesia regimens for reducing patient-reported pain, opioid consumption, and postoperative length of stay (LOS). - Source: PubMed
Publication date: 2026/08/20
Chamberlain VictoriaShern Tyler PHolt Logan RGadd Michele AVerdial Francys CKwait Rebecca MOzmen TolgaSpecht Michelle CSmith Barbara L - Acute appendicitis is the most common surgical emergency in children, and laparoscopic appendectomy has become the standard of care. Enhanced recovery after surgery (ERAS) protocols have demonstrated significant benefits in adult populations, but their application in pediatric emergency surgery remains less established. - Source: PubMed
Publication date: 2026/08/05
Wang DiZhu RongkunMa XiaoxuanZhao JingShang CongHao Xiwei