Ask about this productRelated genes to: DPP3 antibody
- Gene:
- DPP3 NIH gene
- Name:
- dipeptidyl peptidase 3
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 11q13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1999-05-25
- Date modifiied:
- 2016-02-05
Related products to: DPP3 antibody
Related articles to: DPP3 antibody
- Colorectal cancer (CRC) exhibits high morbidity/mortality with poor late-stage survival, creating an urgent need for effective therapies. Although lycorine, a pyrrolophenanthridine alkaloid isolated from the traditional Chinese herb Lycoris radiata, has been confirmed to exhibit significant anti-CRC activity. the exact biological mechanism of its action remains unclear PURPOSE: The present study aimed to clarify whether lycorine exerts its anti-CRC effect by inducing ferroptosis in CRC cells (HCT-116 and RKO), and to elucidate its specific molecular mechanism. - Source: PubMed
Publication date: 2026/04/19
Sheng JuanAn QixianYu FubingXiao YuliangDing HuifengWu LijuanDuan GuanyuYangyin TiantianChen HanWang JiaYao SihanZhang Yinhong - - Source: PubMed
Publication date: 2026/03/25
van Lier DirkSantos KarineHartmann OliverKox MatthijsPickkers Peter - Dipeptidylpeptidase 3 (DPP3) is a ubiquitous intracellular peptidase recently identified in the circulation (cDPP3) as a biomarker and therapeutic target in circulatory failure. The source and mechanism of DPP3 release remain unclear. Based on increased DPP3 expression in the bone marrow compartment under stress conditions, we aimed to assess bone marrow's contribution to DPP3 release. WT bone marrow was transplanted into irradiated DPP3-knockout (KO) mice, generating KO mice, which recovered 44% of baseline cDPP3 activity. In stressed KO mice, cDPP3 increase was comparable to stressed WT mice. DPP3 injection in WT mice induced cardiac neutrophil infiltration. Extracellular vesicles from plasma and bone marrow carried only a minimal fraction of DPP3, indicating mainly soluble release. These results reveal bone marrow-derived cells as a main driver of cDPP3 release under stress and provide a foundation to optimize its use as a biomarker and therapeutic target. - Source: PubMed
Publication date: 2026/02/20
Assad NomaNordin HugoNguyen AlexisOddos ClaireMarguerit GwendolynDelgado LalouSchiltz IsabellePicod AdrienZalc MaximeBeurton AntoineTanguy MarionRautou Pierre-EmmanuelSadoune MalhaPolidano EvelyneLaunay Jean-MarieSantos KarineVodovar NicolasOuattara AlexandreLogeart DamienCalmont AmélieMebazaa AlexandreAzibani Feriel - - Source: PubMed
Publication date: 2026/03/03
Picod AdrienBoussier JeremyTubiana SarahLouis GuillaumeLefevre Laurent MartinTiteca-Beauport DimitriCombe Béatrice LaBesset SébastienBadie JulioChevrel GuillaumeChudeau NicolasBarbar SaberVinsonneau ChristopheForel Jean-MarieThevenin DidierLacave GuillaumeNseir SaadOziel JohannaMayaux JulienKlouche KadaReignier JeanRicard Jean-DamienQuenot Jean-PierreMebazaa AlexandreAzibani FerielDreyfuss DidierGaudry StéphaneChaïbi Khalil - - Source: PubMed
Publication date: 2026/02/06
Teixeira J PedroSchaich Christopher LTen Lohuis Caitlin CNielsen Nathan DChen PeterGinde Adit AHager David NKhan AkramMerck Lisa HSafdar BasmahSturek Jeffrey Mde Wit MarjoleinHarkins Michelle SSelf Wesley HCollins Sean PBusse Laurence W