Ask about this productRelated genes to: ANXA10 antibody
- Gene:
- ANXA10 NIH gene
- Name:
- annexin A10
- Previous symbol:
- -
- Synonyms:
- ANX14
- Chromosome:
- 4q32.3
- Locus Type:
- gene with protein product
- Date approved:
- 1999-09-17
- Date modifiied:
- 2014-11-18
Related products to: ANXA10 antibody
Related articles to: ANXA10 antibody
- Esophageal squamous cell carcinoma (ESCC) significantly impacts public health. Variability exists in patients' responses to chemoradiotherapy (CRT), and the role of purinergic signaling (PS) in ESCC, related to tumor migration, remains unclear. - Source: PubMed
Publication date: 2026/03/17
Zhan XiangZhou FenggeYang YuanhuiLei LingliLi MiaoLi JixianFeng AleiQu YanZeng RenyaYang Zhe - Trastuzumab is the first-line therapy for human epidermal growth factor receptor-2 (HER2)-positive gastric cancer (GC). However, intrinsic and acquired resistance due to hyperactivation of intracellular signaling pathway such as MEK/ERK pathways limit its clinical benefits. Plant-derived bioactive compounds have emerged as promising candidates to overcome trastuzumab resistance due to their multi-target effects and favorable safety profiles. - Source: PubMed
Publication date: 2026/03/02
Zhao HuimingYang JumeiYu HongweiLiu HaotianHe QichenLi ZhengyangPan FeifeiWu LeleShi WenguiJiao Zuoyi - The lack of specific and immunocompetent gastric cancer models has hindered the exploration of gastric adenocarcinoma (GAC). We constructed a spontaneous and transplantable GAC model using a genetically engineered mouse. - Source: PubMed
Publication date: 2026/02/03
Madeti YelizhatiChong XiaoyiZhang Xiaotian - The stomach has been a highly conserved organ throughout vertebrate evolution; however, there are now over 20 lineages composed of monotremes, lungfish and teleost fish displaying a secondary loss of stomach function and morphology. This "agastric phenotype" has evolved convergently and is typified by a loss of gastric glands and gastric acid secretion and a near-to-complete loss of storage capacity of the stomach. All agastric species have lost the genes for gastric enzymes ( and ) and proton pump subunits ( and ), and gastrin () has been lost in monotremes. As a key gastric hormone, the conservation of gastrin has not yet been investigated in the lungfish or agastric teleosts, and it is unclear how the loss of gastrin affects the evolution and selection of the native receptor (), gastrin-releasing peptide () and gastrin-releasing peptide receptor () in vertebrates. Furthermore, there are still many genes implicated in gastric development and function which have yet to be associated with the agastric phenotype. We analysed the evolution, selection and conservation of the gastrin pathway and a novel gastric gene repertoire (, , , , and ) to determine the correlation with the agastric phenotype. We found that the loss of gastrin or its associated genes does not correlate with the agastric phenotype, and their conservation is due to multiple pleiotropic roles throughout vertebrate evolution. We found a loss of the gastric gene repertoire in the agastric phenotype, except in the echidna, which retained several genes (, and ). Our findings suggest that the gastrin physiological pathway evolved differently in pleiotropic roles throughout vertebrate evolution and support the convergent evolution of the agastric phenotype through shared independent gene-loss events. - Source: PubMed
Publication date: 2025/08/05
Dann JacksonGrützner Frank - In the original publication [...]. - Source: PubMed
Publication date: 2025/07/17
Hung Ming-SzuChen Yi-ChuanLin Paul-YannLi Ya-ChinHsu Chia-ChenLung Jr-HauYou LiangXu ZhidongMao Jian-HuaJablons David MYang Cheng-Ta