Ask about this productRelated genes to: ADI1 antibody
- Gene:
- ADI1 NIH gene
- Name:
- acireductone dioxygenase 1
- Previous symbol:
- -
- Synonyms:
- SIPL, MTCBP-1, ARD, APL1, FLJ10913, HMFT1638, mtnD
- Chromosome:
- 2p25.3
- Locus Type:
- gene with protein product
- Date approved:
- 2006-02-09
- Date modifiied:
- 2016-10-05
Related products to: ADI1 antibody
Related articles to: ADI1 antibody
- Obesity is strongly associated with hepatocellular carcinoma (HCC), yet the molecular mechanisms linking them remain unclear. This study aimed to identify mitochondrial metabolism-related genes bridging obesity and HCC and to investigate their role in regulating the metabolic-immune microenvironment. - Source: PubMed
Publication date: 2026/03/09
Li XiaocanMin Rui - The impacts of air pollution on human health have become a major concern, especially with rising greenhouse gas emissions and urban development. This study investigates the molecular mechanisms using the STITCH 4.0 and STRING 9.0 databases to analyze the interaction networks (PCI and PPI) associated with two air pollutants: carbon monoxide and hydrogen sulfide. The functional and pathway analysis related to these pollutants were performed by OmicsBox v.3.0. Additionally, critical proteins and their essential pathways were also identified by the Cytoscape networking tool v.3.10.3. AutoDock vina was employed to hypothetically determine the direct interactions of CO and HS with the proteins that were found by STITCH. This study revealed that CO and HS interacted with the different biological processes related to human health, including erythropoiesis, oxidative stress, energy production, amino acids metabolism, and multiple signaling pathways associated with respiratory, cardiovascular, and neurological functions. Six essential proteins were identified based on their degree of centrality, namely, FECH, HMOX1, ALB, CTH, CBS, and CBSL, which regulate various Reactome and KEGG pathways. Molecular docking analysis revealed that CO exhibited a strong interaction with ADI1, demonstrating a binding affinity of -1.9 kcal/mL. Alternately, the binding energy associated with the HS interaction was notably weak (below -0.9 kcal/mL). This present research highlights the necessity for ongoing investigation into the molecular effects of air pollution to guide public health policies and interventions. - Source: PubMed
Publication date: 2025/03/13
Sheikh Md RamjanMahmud Hasna HeenaHossen Md SaikatSaha DishaUddin Md EkhlasHossain Md FuadMunshi Md KamruzzamanSina Abu Ali Ibn - Socioeconomic status has been recognized as a crucial social determinant of health influencing patient outcomes. Area Deprivation Index (ADI) is a validated measure of an area's socioeconomic status. Limited data exists on the impact of ADI and clinical outcomes and complications following rotator cuff repair (RCR). The purpose of this study was to investigate the impact socioeconomic factors have on outcomes following primary arthroscopic RCR. - Source: PubMed
Publication date: 2024/12/23
Timoteo TaylorNerys-Figueroa JulioKeinath CassandraMovassaghi AghdasDaher NicholasJurayj AlexanderMahylis Jared MMuh Stephanie J - Despite the impressive outcomes with immune checkpoint inhibitor (ICI) in non-small cell lung cancer (NSCLC), only a minority of the patients show long-term benefits from ICI. In this study, we used retrospective cohorts of ICI treated patients with NSCLC to discover and validate spatially resolved protein markers associated with resistance to programmed cell death protein-1 (PD-1) axis inhibition. - Source: PubMed
Publication date: 2024/06/10
Moutafi Myrto KBates Katherine MAung Thazin NweMilian Rolando GarciaXirou VasilikiVathiotis Ioannis AGavrielatou NikiAngelakis AthanasiosSchalper Kurt ASalichos LeonidasRimm David L - Itaconic acid is a promising biochemical building block that can be used in polymer synthesis. Itaconic acid is currently produced in industry by the natural producer fungus Aspergillus terreus using glucose as a main carbon source. Most research for itaconic acid production using lignocellulosic-based carbon sources was carried out by A. terreus. Engineered Corynebacterium glutamicum strain which can grow in presence of fermentation inhibitors without effect on growth, was used for production of itaconic acid using sweet sorghum juice and bagasse sugar lysate (BSL). BSL contains many inhibitors unlike sorghum juice. C. glutamicum could grow in the media containing both types of lignocellulose-based carbon sources without showing any growth inhibition, however, sorghum juice was better in itaconic acid production than BSL. Different constructed strains of C. glutamicum were used for itaconic acid production, however, C. glutamicum ATCC 13032 pCH-Tad1Adi1 strain expressing Adi1/Tad1 genes (trans-pathway) from Ustilago maydis proved to be better in itaconic acid production giving final titer of 8.4 and 4.02 g/L using sweet sorghum juice and BSL as the sole carbon sources by fed-batch fermentation. Our study is the first for production of itaconic acid using sweet sorghum juice and BSL. The present study also proved that C. glutamicum can be used for enhancing itaconic acid production using lignocellulosic-based carbon sources. - Source: PubMed
Publication date: 2023/10/12
Elkasaby TaghreedHanh Dao DuyKahar PrihardiKawaguchi HideoSazuka TakashiKondo AkihikoOgino Chiaki