Ask about this productRelated genes to: ADH1B antibody
- Gene:
- ADH1B NIH gene
- Name:
- alcohol dehydrogenase 1B (class I), beta polypeptide
- Previous symbol:
- ADH2
- Synonyms:
- -
- Chromosome:
- 4q23
- Locus Type:
- gene with protein product
- Date approved:
- 1986-01-01
- Date modifiied:
- 2019-01-18
Related products to: ADH1B antibody
Related articles to: ADH1B antibody
- The prevalence of restless legs syndrome (RLS) among Japanese pregnant women surveyed from 2020 to 2021 was 17.2%, which is higher than that in the general adult population. The onset of this condition involves various factors against a background of genetic predisposition. The presence of the ALDH2*2 allele has been linked to Parkinson's disease, but its association with RLS remains unexamined. This study aimed to clarify the relationship between ALDH2 polymorphism as well as ADH1B polymorphism-already reported to be associated with RLS-and RLS in pregnant women. - Source: PubMed
Publication date: 2026/09/08
Kawahara NatsumiInoue SahoKohtoku YorikoShuo TakuyaTokiya MikikoMatsumoto AkikoEto HiromiKondo Hideaki - Aortic aneurysm (AA) is a life-threatening cardiovascular condition with a strong genetic component, however, its molecular mechanisms remain poorly understood. Although genome-wide association studies (GWAS) have identified numerous risk loci, most prior studies have investigated genetic and metabolic factors separately, leaving the causal pathways from genetic variants to disease largely unexplored. - Source: PubMed
Publication date: 2026/08/24
Wang HanxiCheng JunjieYao JialiJin WentaoLi Wei - Alcohol consumption remains a leading preventable cause of morbidity and mortality; however, abstinence counseling is not routinely implemented in general internal medicine. This review proposes a Japan-oriented framework for translating the diagnosis of alcohol-related diseases into behavioral change interventions. Central to this framework is the concept of the "teachable moment," in which a new diagnosis increases patient motivation and creates opportunities for timely clinical intervention. We reviewed common alcohol-related conditions, including liver disease, alcohol-related cancers, acute pancreatitis, atrial fibrillation, hypertension, hypertriglyceridemia, gout, sleep disorders, and pneumonia, and summarized the evidence that abstinence or reduced alcohol consumption can improve outcomes. We also present an integrated approach that combines brief intervention, liver function-guided pharmacotherapy, nutritional rehabilitation, and specialist collaboration. ALDH2 and ADH1B polymorphisms, common in East Asians, may aid in risk stratification and treatment selection. - Source: PubMed
Publication date: 2026/09/01
Tadokoro TomokoMorishita AsahiroImado RyosukeYano RieNakahara MaiOura KyokoFujita KojiMimura ShimaTani JojiKobara Hideki - Genetic clusters related to Type 2 diabetes (T2D) have differential impact on cardiovascular diseases (CVDs), although the underlying mechanisms, such as proteomic perturbation, remain unexplored. We conducted a network Mendelian randomisation (MR) study to identify proteomic mediators linking T2D genetic clusters and CVDs. - Source: PubMed
Publication date: 2026/08/24
Liao ShuangSung Gabriel Chun YinLiang YiwenLi ChenxiAu Yeung Shiu Lun - Depression, anxiety, and post-traumatic stress disorder (PTSD) are common, militarily relevant mental health disorders that severely impact operational readiness and can disqualify service members from flying class and special duty positions. While observational studies frequently correlate heavy alcohol consumption with these conditions, distinguishing direct causation from reverse causality (e.g., "chemical coping") remains difficult. This study uses Mendelian Randomization (MR) to estimate the causal effect of alcohol consumption on depression, anxiety, PTSD, and alcohol use disorders. - Source: PubMed
Publication date: 2026/08/07
Cornell LaurenShukla TarjaniMcMillan KatherineGdovin MatthewSmetana ChristineRohena LuisDalgard CliftonBlackburn August