Ask about this productRelated genes to: TBCB Blocking Peptide
- Gene:
- TBCB NIH gene
- Name:
- tubulin folding cofactor B
- Previous symbol:
- CKAP1
- Synonyms:
- CG22, CKAPI
- Chromosome:
- 19q13.12
- Locus Type:
- gene with protein product
- Date approved:
- 1995-09-15
- Date modifiied:
- 2016-10-05
Related products to: TBCB Blocking Peptide
Related articles to: TBCB Blocking Peptide
- To evaluate clinical outcomes (performance-based tests and patient-reported outcome measures [PROMs]) and biomechanical measures of movement smoothness, and explore their associations with molecular markers in individuals with knee osteoarthritis (KOA). - Source: PubMed
Publication date: 2026/07/30
Gawelowicz KarolSimonsen Morten BildeHedström MargaretaBroström EvaAulin CeciliaNaili Josefine E - In the AQuIRE trial, most cases (83.6%) did not involve transbronchial needle aspiration (TBNA), often underutilized due to challenges in accessing peripheral pulmonary lesions (PPLs). Advances in robotic bronchoscopy with shape-sensing technology (ssRAB) have mitigated these challenges, but the optimal number of needle and cryoprobe passes for reliable diagnosis remains undefined. - Source: PubMed
Publication date: 2026/08/03
Odeh TariqHegde VishwajitChen MaggieHaworth StevenPostigo Maykol - Accurate diagnosis of peripheral pulmonary lesions (PPLs) remains challenging. Conventional forceps biopsy frequently yields small samples compromised by crush artifact. Transbronchial cryobiopsy (TBCB) offers larger, better-preserved specimens. This study evaluated the diagnostic yield and safety of radial endobronchial ultrasound (r-EBUS)-guided TBCB using a 1.1-mm cryoprobe. - Source: PubMed
Chrif Morand LamyaBouti KhalidSaidi ImaneFdil SoumiaRafik Anis - Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) remains the standard minimally invasive approach for diagnosing and staging thoracic pathology, yet needle aspiration alone often yields limited sensitivity and insufficient tissue for molecular profiling, and while forceps and cryobiopsy techniques can improve diagnostic yield, advancing conventional instruments to a target lesion is not always technically feasible. We report our institutional experience using a 1,470 nm diode laser as an adjunct to EBUS-guided transbronchial tissue acquisition to overcome these access limitations and enhance diagnostic yield. We performed a single-center retrospective case series of patients undergoing laser-assisted EBUS-guided transbronchial cryobiopsy (LA-EBUS-TBCB) or forceps biopsy (LA-EBUS-TBFB) following Institutional Review Board approval, with collected variables including patient demographics, procedural indications, lesion characteristics, laser parameters, diagnostic adequacy, and complications; reporting followed the Preferred Reporting of Case Series in Surgery (PROCESS) 2023 guidelines. Forty-seven patients (mean age 63.9 years; 53.1% male) underwent laser-assisted EBUS-guided biopsy using forceps, cryoprobe, or both, predominantly for diagnostic purposes (87.2%), with lymph node sampling performed in 76.5% of cases, most frequently targeting station 7 (40.4%) and station 4R (31.9%). All procedures used a 1,470 nm diode laser, most commonly at 1-watt power (63.8%). Diagnostic adequacy on pathology review was achieved in 93.6% of cases (44/47), compared with 85.1% (40/47) by cytology alone, an absolute improvement of 8.5 percentage points that recovered definitive tissue diagnoses in 4 of 7 otherwise non-diagnostic cases, and no laser-related bleeding, bronchospasm, airway injury, or fire events occurred. These findings suggest that laser-assisted EBUS-guided transbronchial biopsy using a 1,470 nm diode laser is safe and technically feasible, with high diagnostic adequacy and a favorable complication profile, and may help overcome access limitations encountered with conventional instrumentation, though larger prospective studies are warranted to validate these results, optimize procedural parameters, and define its role relative to standard EBUS-TBNA techniques. - Source: PubMed
Publication date: 2026/05/18
Jain AshishMunoz JonathanVaccarello AnthonyFeghali ElioAbdullah KhaledDammad Tarek - To identify radiologic computed tomography (CT) predictors of increased diagnostic yield and fewer complications in transbronchial lung cryobiopsy (TBCB). - Source: PubMed
Publication date: 2026/07/02
Charokopos AntoniosTzouvelekis ArgyriosStultz BenjaminKoo Chi WanKruger LiviaWoodworth Claire FYi Eunhee STzavara CharaKern RyanBaqir MisbahMoua TengRyu Jay H