Ask about this productRelated genes to: RBM18 Blocking Peptide
- Gene:
- RBM18 NIH gene
- Name:
- RNA binding motif protein 18
- Previous symbol:
- -
- Synonyms:
- MGC2734
- Chromosome:
- 9q33.2
- Locus Type:
- gene with protein product
- Date approved:
- 2004-02-09
- Date modifiied:
- 2016-10-05
Related products to: RBM18 Blocking Peptide
Related articles to: RBM18 Blocking Peptide
- The current bioinformatics study was undertaken to analyze the transcriptome of chicken () after influenza A virus challenge. A meta-analysis was carried out to explore the host expression response after challenge with lowly pathogenic avian influenza (LPAI) (H1N1, H2N3, H5N2, H5N3 and H9N2) and with highly pathogenic avian influenza (HPAI) H5N1 strains. To do so, ten microarray datasets obtained from the Gene Expression Omnibus (GEO) database were normalized and meta-analyzed for the LPAI and HPAI host response individually. Different undirected networks were constructed and their metrics determined e.g., degree centrality, closeness centrality, harmonic centrality, subgraph centrality and eigenvector centrality. The results showed that, based on criteria of centrality, the , , , , and genes were the most significant during HPAI challenge, with , , , and having the lowest values. However, for LPAI challenge, , , , , , and genes had the largest values for aforementioned criteria, with , , , , and genes having the lowest values. The results of this study can be used as a basis for future development of treatments/preventions of the effects of avian influenza in chicken. - Source: PubMed
Publication date: 2022/02/26
Pirbaluty Azadeh MoradiMehrban HosseinKadkhodaei SaeidRavash RudabehOryan AhmadGhaderi-Zefrehei MostafaSmith Jacqueline